Acetaminophen, Dextromethorphan Hydrobromide and Doxylamine Succinate

Capsule, Liquid Filled · Oral

Over the counter Antihistamine Sigma-1 Agonist Uncompetitive N-methyl-D-aspartate Receptor Antagonist

Active ingredient

Active ingredients(in each Softgel) Acetaminophen USP 325 mg Dextromethorphan HBr USP 15 mg Doxylamine succinate USP 6.25 mg

Purpose

Purpose Pain reliever/Fever reducer Cough suppressant Antihistamine

Uses

Uses temporarily relieves common cold/flu symptoms: cough due to minor throat & bronchial irritation sore throat headache minor aches & pains fever runny nose & sneezing

Warnings

Warnings Liver warning: This product contains acetaminophen.Severe liver damage may occur if you take more than 8 softgels in 24 hours, which is the maximum daily amount for this product with other drugs containing acetaminophen 3 or more alcoholic drinks every day while using this product Allergy Alert: Acetaminophen may cause severe skin reactions. Symptoms may include: skin reddening blisters rash If a skin reaction occurs, stop use and seek medical help right away Sore throat warning: If sore throat is severe, persists for more than 2 days,is accompanied or followed by fever, headache, rash, nausea or vomiting, consult a doctor promptly.

Do not use

Do not use with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.

Ask a doctor before use

Ask a doctor before use if you have liver disease glaucoma cough that occurs with too much phlegm (mucus) a breathing problem or chronic cough that lasts or as occurs with smoking, asthma, chronic bronchitis or emphysema trouble urinating due to enlarged prostate gland

Ask a doctor or pharmacist

Ask a doctor or pharmacist before use if you are taking sedatives or tranquilizers taking the blood thinning drug warfarin

When using this product

When using this product do not use more than directed excitability may occur, especially in children marked drowsiness may occur avoid alcoholic drinks be careful when driving a motor vehicle or operating machinery alcohol, sedatives, & tranquilizers may increase drowsiness

Stop use and ask a doctor

Stop use and ask a doctor if pain or cough gets worse or lasts more than 7 days fever gets worse or lasts more than 3 days redness or swelling is present new symptoms occur cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition.

Pregnancy or breast-feeding

If pregnant or breast-feeding ask a health professional before use.

Keep out of reach of children

Keep out of reach of children In case of overdose, get medical help or contact a Poison Control Center right away. Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.

Directions

Directions take only as directed do not exceed 8 softgels per 24 hrs adults & children 12 yrs & over 2 softgels with water every 6 hrs children 4 to under 12 yrs ask a doctor children under 4 yrs do not use

Inactive ingredients

Inactive ingredients D&C yellow no. 10, FD&C blue no. 1, gelatin, glycerin, polyethylene glycol 400, povidone, propylene glycol, sorbitol sorbitan solution, water

Label text from the FDA structured product label by Softgel Healthcare Private Limited (revised Jan 28, 2026). Long sections are shortened; the complete label is on DailyMed.

Active ingredients

Acetaminophen, Dextromethorphan Hydrobromide and Doxylamine Succinate NDC products (2)

NDCStrength & formLabelerType
35916-0154Acetaminophen 325 mg/1; Doxylamine Succinate 6.25 mg/1; Dextromethorphan Hydrobromide 15 mg/1
Capsule, Liquid Filled
Softgel Healthcare Private LimitedOTC MONOGRAPH DRUG
35916-0189Acetaminophen 325 mg/1; Dextromethorphan Hydrobromide 10 mg/1; Doxylamine Succinate 6.25 mg/1
Capsule, Liquid Filled
SOFTGEL HEALTHCARE PRIVATE LIMITEDOTC MONOGRAPH DRUG

Frequently asked questions

What is Acetaminophen, Dextromethorphan Hydrobromide and Doxylamine Succinate used for?

Uses temporarily relieves common cold/flu symptoms: cough due to minor throat & bronchial irritation sore throat headache minor aches & pains fever runny nose & sneezing

Who makes Acetaminophen, Dextromethorphan Hydrobromide and Doxylamine Succinate?

Acetaminophen, Dextromethorphan Hydrobromide and Doxylamine Succinate is listed by 2 labelers in the FDA NDC directory, including Softgel Healthcare Private Limited, SOFTGEL HEALTHCARE PRIVATE LIMITED.