Acetaminophen PM
Acetaminophen, Diphenhydramine HCl · Tablet, Coated · Oral
Active ingredient
Active ingredients (in each geltab) Acetaminophen 500 mg Diphenhydramine HCl 25 mg
Purpose
Purpose Pain reliever Nighttime sleep-aid
Uses
Uses temporary relief of occasional headaches and minor aches and pains with accompanying sleeplessness
Warnings
Warnings Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take: more than 4,000 mg of acetaminophen in24 hours with other drugs containing acetaminophen 3 or more alcoholic drinks every day while using this product Allergy alert: Acetaminophen may cause severe skin reactions. Symptoms may include: skin reddening blisters rash If a skin reaction occurs, stop use and seek medical help right away. Do not use with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. with any other product containing diphenhydramine, even one used on skin in children under 12 years of age if you have ever had an allergic reaction to this product or any of its ingredients Ask a doctor before use if you have liver disease a breathing problem such as emphysema or chronic bronchitis trouble urinating due to an enlarged prostate gland glaucoma Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin taking sedatives or tranquilizers When using this product drowsiness will occur avoid alcoholic drinks do not drive a motor vehicle or operate machinery Stop use and ask a doctor if sleeplessness persists continuously for more than 2 weeks. Insomnia may be a symptom of serious underlying medical illness. new symptoms occur redness or swelling is present pain gets worse or lasts more than 10 days fever gets worse or lasts more than 3 days These could be signs of a serious condition. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. Overdose warning: In case of overdose, get medical help or contact a Poison Control Center (1-800-222-1222) right away: Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.
Do not use
Do not use with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. with any other product containing diphenhydramine, even one used on skin in children under 12 years of age if you have ever had an allergic reaction to this product or any of its ingredients
Ask a doctor before use
Ask a doctor before use if you have liver disease a breathing problem such as emphysema or chronic bronchitis trouble urinating due to an enlarged prostate gland glaucoma
Ask a doctor or pharmacist
Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin taking sedatives or tranquilizers
When using this product
When using this product drowsiness will occur avoid alcoholic drinks do not drive a motor vehicle or operate machinery
Stop use and ask a doctor
Stop use and ask a doctor if sleeplessness persists continuously for more than 2 weeks. Insomnia may be a symptom of serious underlying medical illness. new symptoms occur redness or swelling is present pain gets worse or lasts more than 10 days fever gets worse or lasts more than 3 days These could be signs of a serious condition.
Pregnancy or breast-feeding
If pregnant or breast-feeding, ask a health professional before use.
Keep out of reach of children
Keep out of reach of children. Overdose warning: In case of overdose, get medical help or contact a Poison Control Center (1-800-222-1222) right away: Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.
Directions
Directions do not take more than directed (see overdose warning) adults and children 12 years and over: take 2 geltabs at bedtime. Do not take more than 2 geltabs of this product in 24 hours. children under 12 years: do not use
Other information
Other information store between 20-25ºC (68-77ºF) avoid high humidity and excessive heat
Inactive ingredients
Inactive ingredients corn starch, croscarmellose sodium, D&C red #27 aluminum lake, edible black ink, FD&C blue #1 aluminum lake, gelatin, glycerin, hypromellose, maltodextrin, microcrystalline cellulose, polyethylene glycol, povidone, purified water, silicon dioxide, stearic acid, titanium dioxide
Questions?
Questions or comments? Call toll free 1-855-423-2630
Label text from the FDA structured product label by United Natural Foods, Inc. dba UNFI (revised Aug 31, 2026). Long sections are shortened; the complete label is on DailyMed.
Active ingredients
- Diphenhydramine Hydrochloride in 20 products
- Acetaminophen in 20 products
Acetaminophen PM NDC products (20)
| NDC | Strength & form | Labeler | Type |
|---|---|---|---|
| 57344-095 | Acetaminophen 500 mg/1; Diphenhydramine Hydrochloride 25 mg/1 Tablet, Coated | AAA Pharmaceutical, Inc. | OTC MONOGRAPH DRUG |
| 72288-090 | Acetaminophen 500 mg/1; Diphenhydramine Hydrochloride 25 mg/1 Tablet, Film Coated | Amazon.com Services LLC | OTC MONOGRAPH DRUG |
| 55301-235 | Acetaminophen 500 mg/1; Diphenhydramine Hydrochloride 25 mg/1 Tablet, Film Coated | ARMY AND AIR FORCE EXCHANGE SERVICE | OTC MONOGRAPH DRUG |
| 63868-210 | Acetaminophen 500 mg/1; Diphenhydramine Hydrochloride 25 mg/1 Tablet, Coated | CHAIN DRUG MARKETING ASSOCIATION INC | OTC MONOGRAPH DRUG |
| 83324-070 | Acetaminophen 500 mg/1; Diphenhydramine Hydrochloride 25 mg/1 Tablet, Coated | Chain Drug Marketing Association, Inc. | OTC MONOGRAPH DRUG |
| 63981-056 | Acetaminophen 500 mg/1; Diphenhydramine Hydrochloride 25 mg/1 Tablet, Coated | COSTCO WHOLESALE CORPORATION | OTC MONOGRAPH DRUG |
| 69842-956 | Acetaminophen 500 mg/1; Diphenhydramine Hydrochloride 25 mg/1 Tablet, Coated | CVS PHARMACY | OTC MONOGRAPH DRUG |
| 41520-956 | Acetaminophen 500 mg/1; Diphenhydramine Hydrochloride 25 mg/1 Tablet, Coated | FOODHOLD U.S.A., LLC | OTC MONOGRAPH DRUG |
| 81522-095 | Acetaminophen 500 mg/1; Diphenhydramine Hydrochloride 25 mg/1 Tablet, Coated | FSA STORE INC. | OTC MONOGRAPH DRUG |
| 85828-095 | Acetaminophen 500 mg/1; Diphenhydramine Hydrochloride 25 mg/1 Tablet, Coated | Grocery Outlet, Inc. | OTC MONOGRAPH DRUG |
| 72036-171 | Acetaminophen 500 mg/1; Diphenhydramine Hydrochloride 25 mg/1 Tablet, Coated | Harris Teeter | OTC MONOGRAPH DRUG |
| 0904-6731 | Diphenhydramine Hydrochloride 25 mg/1; Acetaminophen 500 mg/1 Tablet, Film Coated | Major Pharmaceuticals | OTC MONOGRAPH DRUG |
| 72476-171 | Acetaminophen 500 mg/1; Diphenhydramine Hydrochloride 25 mg/1 Tablet, Coated | RETAIL BUSINESS SERVICES , LLC. | OTC MONOGRAPH DRUG |
| 68196-556 | Acetaminophen 500 mg/1; Diphenhydramine Hydrochloride 25 mg/1 Tablet, Coated | Sam's West Inc | OTC MONOGRAPH DRUG |
| 73057-352 | Acetaminophen 500 mg/1; Diphenhydramine Hydrochloride 25 mg/1 Tablet, Film Coated | Ulai Health LLC | OTC MONOGRAPH DRUG |
| 41163-956 | Acetaminophen 500 mg/1; Diphenhydramine Hydrochloride 25 mg/1 Tablet, Coated | United Natural Foods, Inc. dba UNFI | OTC MONOGRAPH DRUG |
| 41163-515 | Acetaminophen 500 mg/1; Diphenhydramine Hydrochloride 25 mg/1 Tablet, Coated | United Natural Foods, Inc. dba UNFI | OTC MONOGRAPH DRUG |
| 41163-228 | Acetaminophen 500 mg/1; Diphenhydramine Hydrochloride 25 mg/1 Tablet, Coated | United Natural Foods, Inc. dba UNFI | OTC MONOGRAPH DRUG |
| 67091-137 | Acetaminophen 500 mg/1; Diphenhydramine Hydrochloride 25 mg/1 Tablet, Coated | WinCo Foods, LLC | OTC MONOGRAPH DRUG |
| 17714-133 | Acetaminophen 500 mg/1; Diphenhydramine Hydrochloride 25 mg/1 Tablet | Advance Pharmaceutical Inc. | OTC MONOGRAPH FINAL |
Frequently asked questions
What is Acetaminophen PM used for?
Uses temporary relief of occasional headaches and minor aches and pains with accompanying sleeplessness
Who makes Acetaminophen PM?
Acetaminophen PM is listed by 18 labelers in the FDA NDC directory, including AAA Pharmaceutical, Inc., Amazon.com Services LLC, ARMY AND AIR FORCE EXCHANGE SERVICE, CHAIN DRUG MARKETING ASSOCIATION INC.