ActivICE

Menthol · Spray · Topical

Over the counter

Active ingredient

Active ingredient Menthol 8.0%

Purpose

Purpose Topical Analgesic

Uses

Uses For the temporary relief of minor aches and pains of muscles and joints associated with: simple backache arthritis strains bruises sprains

Warnings

Warnings For external use only. Avoid contact with eyes. Flammable: keep away from fire or flame. When using this product use only as directed do not bandage tightly or use with heating pad do not apply to wounds or damaged skin Stop use and ask doctor if condition worsens, or if symptoms persist for more than 7 days or clear up and occur again within a few days redness is present excessive irritation of the skin develops If pregnant or breastfeeding, ask a health professional before use. Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

When using this product

When using this product use only as directed do not bandage tightly or use with heating pad do not apply to wounds or damaged skin

Stop use and ask a doctor

Stop use and ask doctor if condition worsens, or if symptoms persist for more than 7 days or clear up and occur again within a few days redness is present excessive irritation of the skin develops

Pregnancy or breast-feeding

If pregnant or breastfeeding, ask a health professional before use.

Keep out of reach of children

Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

Directions

Directions Adults and children 2 years of age and older: apply directly onto affected area without the need to rub, massage or bandage repeat if necessary, but do not apply more than 3 to 4 times daily wash hands after use Children under 2 years of age: do not use, consult a doctor.

Inactive ingredients

Inactive ingredients acrylic acid/vinyl ester copolymer, dimethylsulfone (MSM), eucalyptus oil, glucosamine sulfate, hydroxypropylcellulose, PEG-8 dimethicone, pentylene glycol, peppermint oil, SD alcohol 39C, triethanolamine, water (USP)

Questions?

Questions or comments? 1-800-MEDLINE (633-5463) Monday-Friday 9AM-5PM CST

Label text from the FDA structured product label by Medline Industries, LP (revised Sep 1, 2026). Long sections are shortened; the complete label is on DailyMed.

Active ingredients

ActivICE NDC products (4)

NDCStrength & formLabelerType
53329-984Menthol 80 mg/mL
Gel
Medline Industries, LPOTC MONOGRAPH DRUG
53329-991Menthol 80 g/1000g
Spray
Medline Industries, LPOTC MONOGRAPH DRUG
53329-992Menthol 80 g/1000g
Liquid
Medline Industries, LPOTC MONOGRAPH DRUG
53329-996Menthol 100 mg/mL
Spray
Medline Industries, LPOTC MONOGRAPH DRUG

Frequently asked questions

What is ActivICE used for?

Uses For the temporary relief of minor aches and pains of muscles and joints associated with: simple backache arthritis strains bruises sprains

Who makes ActivICE?

ActivICE is listed by 1 labeler in the FDA NDC directory, including Medline Industries, LP.