ALKA SELTZER COLD Cold and Headache Maximum Strength Fast Dissolve
aspirin, chlorpheniramine maleate, phenylephrine bitartrate · Tablet, Effervescent · Oral
Active ingredient
Active ingredients (in each tablet) Aspirin 325 mg (NSAID)* Chlorpheniramine maleate 2 mg Phenylephrine bitartrate 7.8 mg *nonsteroidal anti-inflammatory drug
Purpose
Purposes Pain reliever/fever reducer Antihistamine Nasal decongestant
Uses
Uses Uses · temporarily relieves these symptoms due to a cold: · minor aches and pains · headache · runny nose · nasal congestion · sinus congestion and pressure · sneezing · sore throat · temporarily reduces fever
Warnings
Warnings Reye’s syndrome: Children and teenagers who have or are recovering from chicken pox or flu-like symptoms should not use this product. When using this product, if changes in behavior with nausea and vomiting occur, consult a doctor because these symptoms could be an early sign of Reye’s syndrome, a rare but serious illness. Allergy alert: Aspirin may cause a severe allergic reaction which may include: ● hives ● facial swelling ● asthma (wheezing) ● shock Stomach bleeding warning : This product contains an NSAID, which may cause severe stomach bleeding. The chance is higher if you ● are age 60 or older ● have had stomach ulcers or bleeding problems ● take a blood thinning (anticoagulant) or steroid drug ● take other drugs containing prescription or nonprescription NSAIDs (aspirin, ibuprofen, naproxen, or others) ● have 3 or more alcoholic drinks every day while using this product ● take more or for a longer time than directed Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly. Do not use to sedate children. Do not use ● if you are allergic to aspirin or any other pain reliever/fever reducer ● if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. ● if you have ever had an allergic reaction to this product or any of its ingredients ● in children under 12 years of age Ask a doctor before use if ● stomach bleeding warning applies to you ● you have a history of stomach problems, such as heartburn ● you have high blood pressure, heart disease, liver cirrhosis, or kidney disease ● you are taking a diuretic ● you have ● asthma ● diabetes ● thyroid disease ● glaucoma ● a breathing problem such as emphysema or chronic bronchitis ● difficulty in urination due to enlargement of the prostate gland ● a sodium-restricted diet Ask a doctor or pharmacist before use if you are · taking a prescription drug for diabetes, gout or arthritis · taking sedatives or tranquilizers When using this product ● do not exceed recommended dosage ● may cause drowsiness ● alcohol, sedatives, and tranquilizers may increase the drowsiness effect ● avoid alcoholic drinks ● be careful when driving a motor vehicle or operating machinery ● excitability may occur, especially in children Stop use and ask a doctor if ● an allergic reaction occurs. Seek medical help right away. ● you experience any of the following signs of stomach bleeding ● feel faint ● vomit blood ● have bloody or black stools ● have stomach pain that does not get better ● pain or nasal congestion gets worse or lasts more than 7 days ● fever gets worse or lasts more than 3 days ● redness or swelling is present ● new symptoms occur ● ringing in the ears or a loss of hearing occurs ● nervousness, dizziness, or sleeplessness occur If pregnant or breast-feeding, ask a health professional before use. It is especially important not to use aspirin at 20 weeks or later in pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.
Do not use
Do not use ● if you are allergic to aspirin or any other pain reliever/fever reducer ● if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. ● if you have ever had an allergic reaction to this product or any of its ingredients ● in children under 12 years of age
Ask a doctor before use
Ask a doctor before use if ● stomach bleeding warning applies to you ● you have a history of stomach problems, such as heartburn ● you have high blood pressure, heart disease, liver cirrhosis, or kidney disease ● you are taking a diuretic ● you have ● asthma ● diabetes ● thyroid disease ● glaucoma ● a breathing problem such as emphysema or chronic bronchitis ● difficulty in urination due to enlargement of the prostate gland ● a sodium-restricted diet
Ask a doctor or pharmacist
Ask a doctor or pharmacist before use if you are · taking a prescription drug for diabetes, gout or arthritis · taking sedatives or tranquilizers
When using this product
When using this product ● do not exceed recommended dosage ● may cause drowsiness ● alcohol, sedatives, and tranquilizers may increase the drowsiness effect ● avoid alcoholic drinks ● be careful when driving a motor vehicle or operating machinery ● excitability may occur, especially in children
Stop use and ask a doctor
Stop use and ask a doctor if ● an allergic reaction occurs. Seek medical help right away. ● you experience any of the following signs of stomach bleeding ● feel faint ● vomit blood ● have bloody or black stools ● have stomach pain that does not get better ● pain or nasal congestion gets worse or lasts more than 7 days ● fever gets worse or lasts more than 3 days ● redness or swelling is present ● new symptoms occur ● ringing in the ears or a loss of hearing occurs ● nervousness, dizziness, or sleeplessness occur
Pregnancy or breast-feeding
If pregnant or breast-feeding, ask a health professional before use. It is especially important not to use aspirin at 20 weeks or later in pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery.
Keep out of reach of children
Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.
Directions
Directions Directions ● adults and children 12 years and over: take 2 tablets fully dissolved in 4 oz of water every 4 hours. Do not exceed 8 tablets in 24 hours or as directed by a doctor. ● children under 12 years: do not use
Inactive ingredients
Inactive ingredients Inactive ingredients anhydrous citric acid, calcium silicate, dimethicone, FD&C red #40, FD&C yellow #6, flavor, mannitol, potassium bicarbonate, povidone, sodium bicarbonate, sucralose
Questions?
Questions or Comments Questions or comments? 1-800-986-0369 (Mon – Fri 8AM – 8PM EST)
Label text from the FDA structured product label by Bayer HealthCare LLC. (revised Jul 9, 2026). Long sections are shortened; the complete label is on DailyMed.
Active ingredients
- Phenylephrine Bitartrate in 2 products
- Chlorpheniramine Maleate in 2 products
- Aspirin in 2 products
ALKA SELTZER COLD Cold and Headache Maximum Strength Fast Dissolve NDC products (2)
| NDC | Strength & form | Labeler | Type |
|---|---|---|---|
| 0280-8266 | Phenylephrine Bitartrate 7.8 mg/1; Chlorpheniramine Maleate 2 mg/1; Aspirin 325 mg/1 Tablet, Effervescent | Bayer HealthCare LLC. | OTC MONOGRAPH DRUG |
| 0280-8270 | Aspirin 325 mg/1; Chlorpheniramine Maleate 2 mg/1; Phenylephrine Bitartrate 7.8 mg/1 Tablet, Effervescent | Bayer HealthCare LLC. | OTC MONOGRAPH DRUG |
Frequently asked questions
What is ALKA SELTZER COLD Cold and Headache Maximum Strength Fast Dissolve used for?
Uses Uses · temporarily relieves these symptoms due to a cold: · minor aches and pains · headache · runny nose · nasal congestion · sinus congestion and pressure · sneezing · sore throat · temporarily reduces fever
Who makes ALKA SELTZER COLD Cold and Headache Maximum Strength Fast Dissolve?
ALKA SELTZER COLD Cold and Headache Maximum Strength Fast Dissolve is listed by 1 labeler in the FDA NDC directory, including Bayer HealthCare LLC..