Alka-Seltzer Extra Strength
Anhydrous Citric Acid, Sodium Bicarbonate, and Aspirin · Granule, Effervescent · Oral
Active ingredient
Active ingredients (in each tablet) Purpose Anhydrous citric acid 1000 mg Antacid Aspirin 500 mg Analgesic Sodium bicarbonate (heat-treated) 1985 mg Antacid
Purpose
Active ingredients (in each tablet) Purpose Anhydrous citric acid 1000 mg Antacid Aspirin 500 mg Analgesic Sodium bicarbonate (heat-treated) 1985 mg Antacid
Uses
Uses for the temporary relief of: heartburn, acid indigestion, and sour stomach when accompanied with headache or body aches and pains upset stomach with headache from overindulgence in food or drink headache, body aches, and pain alone
Warnings
Warnings Reye’s syndrome: Children and teenagers who have or are recovering from chicken pox or flu-like symptoms should not use this product. When using this product, if changes in behavior with nausea and vomiting occur, consult a doctor because these symptoms could be an early sign of Reye’s syndrome, a rare but serious illness. Allergy alert: Aspirin may cause a severe allergic reaction which may include hives facial swelling asthma (wheezing) shock Stomach bleeding warning: This product contains an NSAID, which may cause severe stomach bleeding. The chance is higher if you are age 60 or older have had stomach ulcers or bleeding problems take a blood thinning (anticoagulant) or steroid drug take other drugs containing prescription or nonprescription NSAIDs (aspirin, ibuprofen, naproxen, or others) have 3 or more alcoholic drinks every day while using this product take more or for a longer time than directed Do not use if you are allergic to aspirin or any other pain reliever/fever reducer if you have ever had an allergic reaction to this product or any of its ingredients Ask a doctor before use if stomach bleeding warning applies to you you have a history of stomach problems, such as heartburn you have high blood pressure, heart disease, liver cirrhosis, or kidney disease you are taking a diuretic you have asthma you have a sodium-restricted diet Ask a doctor or pharmacist before use if you are presently taking a prescription drug. Antacids may interact with certain prescription drugs. taking a prescription drug for anticoagulation (blood thinning), diabetes, gout, or arthritis When using this product do not exceed recommended dosage Stop use and ask a doctor if an allergic reaction occurs. Seek medical help right away. you experience any of the following signs of stomach bleeding
• feel faint
• vomit blood
• have bloody or black stools
• have stomach pain that does not get better symptoms get worse or last more than 10 days redness or swelling is present ringing in the ears or a loss of hearing occurs new symptoms occur If pregnant or breast-feeding, ask a health professional before use. It is especially important not to use aspirin during the last 3 months of pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.
Do not use
Do not use if you are allergic to aspirin or any other pain reliever/fever reducer if you have ever had an allergic reaction to this product or any of its ingredients
Ask a doctor before use
Ask a doctor before use if stomach bleeding warning applies to you you have a history of stomach problems, such as heartburn you have high blood pressure, heart disease, liver cirrhosis, or kidney disease you are taking a diuretic you have asthma you have a sodium-restricted diet
Ask a doctor or pharmacist
Ask a doctor or pharmacist before use if you are presently taking a prescription drug. Antacids may interact with certain prescription drugs. taking a prescription drug for anticoagulation (blood thinning), diabetes, gout, or arthritis
When using this product
When using this product do not exceed recommended dosage
Stop use and ask a doctor
Stop use and ask a doctor if an allergic reaction occurs. Seek medical help right away. you experience any of the following signs of stomach bleeding
• feel faint
• vomit blood
• have bloody or black stools
• have stomach pain that does not get better symptoms get worse or last more than 10 days redness or swelling is present ringing in the ears or a loss of hearing occurs new symptoms occur
Pregnancy or breast-feeding
If pregnant or breast-feeding, ask a health professional before use. It is especially important not to use aspirin during the last 3 months of pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery.
Keep out of reach of children
Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.
Directions
Directions fully dissolve 2 tablets in 4 ounces of water before taking adults and children 12 years and over 2 tablets every 6 hours, or as directed by a doctor do not exceed 7 tablets in 24 hours adults 60 years and over 2 tablets every 6 hours, or as directed by a doctor do not exceed 3 tablets in 24 hours children under 12 years consult a doctor
Other information
Other information each tablet contains: sodium 588 mg store at room temperature. Avoid excessive heat. Alka-Seltzer Extra Strength in water contains principally the antacid sodium citrate and the analgesic sodium acetylsalicylate
Inactive ingredients
Inactive ingredients flavor
Questions?
Questions or comments? 1-800-986-0369 (Mon - Fri 9AM - 5PM EST)
Label text from the FDA structured product label by Bayer HealthCare LLC. (revised Dec 4, 2025). Long sections are shortened; the complete label is on DailyMed.
Active ingredients
- Anhydrous Citric Acid in 1 product
- Sodium Bicarbonate in 1 product
- Aspirin in 1 product
Alka-Seltzer Extra Strength NDC products (1)
| NDC | Strength & form | Labeler | Type |
|---|---|---|---|
| 0280-0211 | Anhydrous Citric Acid 1000 mg/1; Sodium Bicarbonate 1985 mg/1; Aspirin 500 mg/1 Granule, Effervescent | Bayer HealthCare LLC. | OTC MONOGRAPH DRUG |
Frequently asked questions
What is Alka-Seltzer Extra Strength used for?
Uses for the temporary relief of: heartburn, acid indigestion, and sour stomach when accompanied with headache or body aches and pains upset stomach with headache from overindulgence in food or drink headache, body aches, and pain alone
Who makes Alka-Seltzer Extra Strength?
Alka-Seltzer Extra Strength is listed by 1 labeler in the FDA NDC directory, including Bayer HealthCare LLC..