Allergy Plus Sinus Headache

Acetaminophen, Diphenhydramine HCl and Phenylephrine HCl · Tablet, Film Coated · Oral

Over the counter Histamine-1 Receptor Antagonist alpha-1 Adrenergic Agonist

Active ingredient

Active ingredient (in each caplet) Acetaminophen 325 mg Diphenhydramine HCl 12.5 mg Phenylephrine HCl 5 mg

Purpose

Purpose Pain reliever Antihistamine Nasal decongestant

Uses

Uses temporarily relieves these symptoms of hay fever and the common cold: runny nose sneezing headache minor aches and pains nasal congestion temporarily relieves these additional symptoms of hay fever: itching of the nose or throat itchy, watery eyes

Warnings

Warnings Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take: more than 4,000 mg of acetaminophen in 24 hours with other drugs containing acetaminophen 3 or more alcoholic drinks every day while using this product Allergy alert: Acetaminophen may cause severe skin reactions. Symptoms may include: skin reddening blisters rash hives facial swelling asthma (wheezing) shock If a skin reaction occurs, stop use and seek medical help right away. Do not use with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. with any other product containing diphenhydramine, even one used on skin if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. if you have ever had an allergic reaction to this product or any of its ingredients acetaminophen, ask a doctor or pharmacist.

Ask a doctor before use

Ask a doctor before use if you have liver disease glaucoma thyroid disease heart disease diabetes high blood pressure difficulty in urination due to enlargement of the prostate gland a breathing problem such as emphysema or chronic bronchitis

Ask a doctor or pharmacist

Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin taking sedatives or tranquilizers

When using this product

When using this product do not exceed recommended dosage excitability may occur, especially in children marked drowsiness may occur alcohol, sedatives, and tranquilizers may increase drowsiness use caution when driving a motor vehicle or operating machinery avoid alcoholic beverages

Stop use and ask a doctor

Stop use and ask a doctor if nervousness, dizziness, or sleeplessness occur pain or nasal congestion gets worse or lasts more than 7 days new symptoms occur fever gets worse or lasts more than 3 days redness or swelling is present

Pregnancy or breast-feeding

If pregnant or breast-feeding , ask a health professional before use.

Keep out of reach of children

Keep out of reach of children . In case of overdose, get medical help or contact a Poison Control Center right away.1(800)222-1222

Directions

Directions do not use more than directed adults and children 12 years and over: take 2 caplets every 4 hours do not take more than 10 caplets in 24 hours children under 12 years: ask a doctor

Inactive ingredients

Inactive ingredients croscarmellose sodium, colloidal silicon dioxide, dibasic calcium phosphate, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polyvinyl alcohol, povidone, starch, talc, titanium dioxide

Questions?

Questions or comments? 1-800-373-6981 (toll-free)

Label text from the FDA structured product label by Shield Pharmaceuticals Corp (revised Jul 22, 2026). Long sections are shortened; the complete label is on DailyMed.

Active ingredients

Allergy Plus Sinus Headache NDC products (4)

NDCStrength & formLabelerType
55910-464Acetaminophen 325 mg/1; Diphenhydramine Hydrochloride 12.5 mg/1; Phenylephrine Hydrochloride 5 mg/1
Tablet, Film Coated
DOLGENCORP, LLCOTC MONOGRAPH DRUG
83059-0044Acetaminophen 325 mg/1; Diphenhydramine Hydrochloride 12.5 mg/1; Phenylephrine Hydrochloride 5 mg/1
Tablet, Film Coated
Shield Pharmaceuticals CorpOTC MONOGRAPH DRUG
83059-0106Acetaminophen 325 mg/1; Diphenhydramine Hydrochloride 12.5 mg/1; Phenylephrine Hydrochloride 5 mg/1
Tablet, Film Coated
Shield Pharmaceuticals CorpOTC MONOGRAPH DRUG
83059-0162Acetaminophen 325 mg/1; Diphenhydramine Hydrochloride 12.5 mg/1; Phenylephrine Hydrochloride 5 mg/1
Tablet, Film Coated
Shield Pharmaceuticals CorpOTC MONOGRAPH DRUG

Frequently asked questions

What is Allergy Plus Sinus Headache used for?

Uses temporarily relieves these symptoms of hay fever and the common cold: runny nose sneezing headache minor aches and pains nasal congestion temporarily relieves these additional symptoms of hay fever: itching of the nose or throat itchy, watery eyes

Who makes Allergy Plus Sinus Headache?

Allergy Plus Sinus Headache is listed by 2 labelers in the FDA NDC directory, including DOLGENCORP, LLC, Shield Pharmaceuticals Corp.