Aprodine

Pseudoephedrine HCl, Triprolidine HCl · Tablet, Film Coated · Oral

Over the counter alpha-Adrenergic Agonist

Active ingredient

Active ingredients (in each tablet) Pseudoephedrine HCl 60 mg Triprolidine HCl 2.5 mg

Purpose

Purpose Nasal decongestant Antihistamine

Uses

Uses temporarily relieves these symptoms due to hay fever (allergic rhinitis) or other upper respiratory allergies: runny nose itchy, watery eyes nasal congestion sneezing itching of the nose or throat temporarily relieves these symptoms due to the common cold: runny nose sneezing nasal congestion

Warnings

Warnings Do not use if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. Ask a doctor before use if you have high blood pressure heart disease thyroid disease diabetes glaucoma a breathing problem such as emphysema or chronic bronchitis difficulty in urination due to enlargement of the prostate gland Ask a doctor or pharmacist before use if you are taking sedatives or tranquilizers. When using this product do not exceed recommended dosage excitability may occur, especially in children use caution when driving a motor vehicle or operating machinery drowsiness may occur avoid alcoholic beverages alcohol, sedatives, and tranquilizers may increase drowsiness Stop use and ask a doctor if nervousness, dizziness, or sleeplessness occur symptoms do not improve within 7 days or occur with fever If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.

Do not use

Do not use if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.

Ask a doctor before use

Ask a doctor before use if you have high blood pressure heart disease thyroid disease diabetes glaucoma a breathing problem such as emphysema or chronic bronchitis difficulty in urination due to enlargement of the prostate gland

Ask a doctor or pharmacist

Ask a doctor or pharmacist before use if you are taking sedatives or tranquilizers.

When using this product

When using this product do not exceed recommended dosage excitability may occur, especially in children use caution when driving a motor vehicle or operating machinery drowsiness may occur avoid alcoholic beverages alcohol, sedatives, and tranquilizers may increase drowsiness

Stop use and ask a doctor

Stop use and ask a doctor if nervousness, dizziness, or sleeplessness occur symptoms do not improve within 7 days or occur with fever

Pregnancy or breast-feeding

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children

Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.

Directions

Directions do not take more than directed adults and children 12 years and over: take 1 tablet every 4 to 6 hours. Do not take more than 4 tablets in 24 hours. children under 12 years: do not use

Other information

Other information TAMPER EVIDENT: DO NOT USE IF OUTER PACKAGE IS OPENED OR BLISTER IS TORN OR BROKEN store at 25°C (77°F); excursions permitted between 15°-30°C (59°-86°F) see end flap for expiration date and lot number

Inactive ingredients

Inactive ingredients hypromellose, magnesium stearate, polyethylene glycol, silicified microcrystalline cellulose, titanium dioxide

Questions?

Questions or comments? 1-800-426-9391

Label text from the FDA structured product label by Major Pharmaceuticals (revised Nov 19, 2025). Long sections are shortened; the complete label is on DailyMed.

Active ingredients

Aprodine NDC products (2)

NDCStrength & formLabelerType
50090-7085Pseudoephedrine Hydrochloride 60 mg/1; Triprolidine Hydrochloride 2.5 mg/1
Tablet, Film Coated
A-S Medication SolutionsOTC MONOGRAPH DRUG
0904-7302Pseudoephedrine Hydrochloride 60 mg/1; Triprolidine Hydrochloride 2.5 mg/1
Tablet, Film Coated
Major PharmaceuticalsOTC MONOGRAPH DRUG

Frequently asked questions

What is Aprodine used for?

Uses temporarily relieves these symptoms due to hay fever (allergic rhinitis) or other upper respiratory allergies: runny nose itchy, watery eyes nasal congestion sneezing itching of the nose or throat temporarily relieves these symptoms due to the common cold: runny nose sneezing nasal congestion

Who makes Aprodine?

Aprodine is listed by 2 labelers in the FDA NDC directory, including A-S Medication Solutions, Major Pharmaceuticals.