Benadryl
Diphenhydramine Hydrochloride · Tablet, Film Coated · Oral
Active ingredient
Active ingredient (in each tablet) Diphenhydramine HCl 25 mg
Purpose
Purpose Antihistamine
Uses
Uses temporarily relieves these symptoms due to hay fever or other upper respiratory allergies: runny nose sneezing itchy, watery eyes itching of the nose or throat temporarily relieves these symptoms due to the common cold: runny nose sneezing
Warnings
Warnings Do not use to make a child sleepy with any other product containing diphenhydramine, even one used on skin Ask a doctor before use if you have a breathing problem such as emphysema or chronic bronchitis glaucoma trouble urinating due to an enlarged prostate gland Ask a doctor or pharmacist before use if you are taking sedatives or tranquilizers When using this product marked drowsiness may occur avoid alcoholic drinks alcohol, sedatives, and tranquilizers may increase drowsiness be careful when driving a motor vehicle or operating machinery excitability may occur, especially in children If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222)
Do not use
Do not use to make a child sleepy with any other product containing diphenhydramine, even one used on skin
Ask a doctor before use
Ask a doctor before use if you have a breathing problem such as emphysema or chronic bronchitis glaucoma trouble urinating due to an enlarged prostate gland
Ask a doctor or pharmacist
Ask a doctor or pharmacist before use if you are taking sedatives or tranquilizers
When using this product
When using this product marked drowsiness may occur avoid alcoholic drinks alcohol, sedatives, and tranquilizers may increase drowsiness be careful when driving a motor vehicle or operating machinery excitability may occur, especially in children
Pregnancy or breast-feeding
If pregnant or breast-feeding, ask a health professional before use.
Keep out of reach of children
Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222)
Directions
Directions take every 4 to 6 hours, or as directed by a doctor do not take more than 6 times in 24 hours adults and children 12 years and over 1 to 2 tablets children 6 to under 12 years 1 tablet children under 6 years do not use
Other information
Other information each tablet contains: calcium 15 mg store between 20-25°C (68-77°F). Protect from light. do not use if blister unit is torn or broken
Inactive ingredients
Inactive ingredients carnauba wax, croscarmellose sodium, D&C red no. 27 aluminum lake, dibasic calcium phosphate, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate 80, titanium dioxide
Questions?
Questions or comments? call 1-877-717-2824 (toll-free) or 215-273-8755 (collect)
Label text from the FDA structured product label by Kenvue Brands LLC (revised Jul 28, 2026). Long sections are shortened; the complete label is on DailyMed.
Active ingredients
- Diphenhydramine Hydrochloride in 7 products
Benadryl NDC products (8)
| NDC | Strength & form | Labeler | Type |
|---|---|---|---|
| 50580-226 | Diphenhydramine Hydrochloride 25 mg/1 Tablet, Film Coated | Kenvue Brands LLC | OTC MONOGRAPH DRUG |
| 50580-370 | Kit | Kenvue Brands LLC | OTC MONOGRAPH DRUG |
| 66715-6406 | Diphenhydramine Hydrochloride 25 mg/1 Tablet, Film Coated | Lil' Drug Store Products, Inc. | OTC MONOGRAPH DRUG |
| 66715-6506 | Diphenhydramine Hydrochloride 25 mg/1 Tablet, Film Coated | Lil' Drug Store Products, Inc. | OTC MONOGRAPH DRUG |
| 66715-9706 | Diphenhydramine Hydrochloride 25 mg/1 Tablet, Film Coated | Lil' Drug Store Products, Inc. | OTC MONOGRAPH DRUG |
| 53209-3001 | Diphenhydramine Hydrochloride 25 mg/1 Tablet, Film Coated | Morning Star OTC | OTC MONOGRAPH DRUG |
| 71205-521 | Diphenhydramine Hydrochloride 25 mg/1 Tablet, Film Coated | Proficient Rx LP | OTC MONOGRAPH DRUG |
| 85237-1960 | Diphenhydramine Hydrochloride 25 mg/1 Tablet, Film Coated | Select Consumer Group | OTC MONOGRAPH DRUG |
Frequently asked questions
What is Benadryl used for?
Uses temporarily relieves these symptoms due to hay fever or other upper respiratory allergies: runny nose sneezing itchy, watery eyes itching of the nose or throat temporarily relieves these symptoms due to the common cold: runny nose sneezing
Who makes Benadryl?
Benadryl is listed by 5 labelers in the FDA NDC directory, including Kenvue Brands LLC, Lil' Drug Store Products, Inc., Morning Star OTC, Proficient Rx LP.