Buffered Aspirin

Aspirin · Tablet, Film Coated · Oral

Over the counter Nonsteroidal Anti-inflammatory Drug Platelet Aggregation Inhibitor

Active ingredient

Active ingredient ( in each tablet) Buffered aspirin equal to 325 mg aspirin (NSAID)* (buffered with calcium carbonate, magnesium carbonate, and magnesium oxide) *nonsteroidal anti-inflammatory drug

Purpose

Purpose Pain reliever/fever reducer

Uses

Uses temporarily relieves minor aches and pains associated with: toothache minor pain of arthritis backache the common cold headache muscular aches premenstrual & menstrual cramps temporarily reduces fever

Warnings

Warnings Reye’s syndrome: Children and teenagers who have or are recovering from chicken pox or flu-like symptoms should not use this product. When using this product, if changes in behavior with nausea and vomiting occur, consult a doctor because these symptoms could be an early sign of Reye's syndrome, a rare but serious illness. Allergy alert: Aspirin may cause a severe allergic reaction, which may include: shock hives asthma (wheezing) facial swelling Stomach bleeding warning: This product contains an NSAID, which may cause severe stomach bleeding. The chance is higher if you have had stomach ulcers or bleeding problems have 3 or more alcoholic drinks every day while using this product are age 60 or older take a blood thinning (anticoagulant) or steroid drug take other drugs containing prescription or nonprescription NSAIDs [aspirin, ibuprofen, naproxen, or others] take more or for a longer time than directed Do not use if you are allergic to aspirin or any other pain reliever/fever reducer if you have ever had an allergic reaction to this product or any of its ingredients Ask a doctor before use if stomach bleeding warning applies to you you have a history of stomach problems, such as heartburn you have asthma you are taking a diuretic you have high blood pressure, heart disease, liver cirrhosis, or kidney disease Ask a doctor or pharmacist before use if you are taking a prescription drug for gout diabetes arthritis Stop use and ask a doctor if an allergic reaction occurs. Seek medical help right away. you experience any of the following signs of stomach bleeding: feel faint vomit blood have bloody or black stools have stomach pain that does not get better ringing in the ears or a loss of hearing occurs pain gets worse or lasts more than 10 days fever gets worse or lasts more than 3 days redness or swelling is present new symptoms occur These could be signs of a serious condition. If pregnant or breast-feeding, ask a health professional before use. It is especially important not to use aspirin at 20 weeks or later in pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.

Do not use

Do not use if you are allergic to aspirin or any other pain reliever/fever reducer if you have ever had an allergic reaction to this product or any of its ingredients

Ask a doctor before use

Ask a doctor before use if stomach bleeding warning applies to you you have a history of stomach problems, such as heartburn you have asthma you are taking a diuretic you have high blood pressure, heart disease, liver cirrhosis, or kidney disease

Ask a doctor or pharmacist

Ask a doctor or pharmacist before use if you are taking a prescription drug for gout diabetes arthritis

Stop use and ask a doctor

Stop use and ask a doctor if an allergic reaction occurs. Seek medical help right away. you experience any of the following signs of stomach bleeding: feel faint vomit blood have bloody or black stools have stomach pain that does not get better ringing in the ears or a loss of hearing occurs pain gets worse or lasts more than 10 days fever gets worse or lasts more than 3 days redness or swelling is present new symptoms occur These could be signs of a serious condition.

Pregnancy or breast-feeding

If pregnant or breast-feeding, ask a health professional before use. It is especially important not to use aspirin at 20 weeks or later in pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery.

Keep out of reach of children

Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.

Directions

Directions do not take more than directed drink a full glass of water with each dose adults and children 12 years and over: take 2 tablets every 4 hours not to exceed 12 tablets in 24 hours unless directed by a doctor children under 12 years: do not use unless directed by a doctor

Other information

Other information each tablet contains: calcium 35 mg and magnesium 45 mg store at 25°C (77°F); excursions permitted between 15°-30°C (59°-86°F) see end flap for expiration date and lot number

Inactive ingredients

Inactive ingredients anhydrous citric acid, corn starch, dibasic sodium phosphate anhydrous, hydrogenated vegetable oil, hypromellose, microcrystalline cellulose, polyethylene glycol, propylene glycol, shellac wax, simethicone, sodium lauryl sulfate, talc, titanium dioxide

Questions?

Questions or comments? 1-800-426-9391

Label text from the FDA structured product label by Cardinal Health 110, LLC. DBA Leader (revised Feb 6, 2026). Long sections are shortened; the complete label is on DailyMed.

Active ingredients

Buffered Aspirin NDC products (1)

NDCStrength & formLabelerType
70000-0147Aspirin 325 mg/1
Tablet, Film Coated
Cardinal Health 110, LLC. DBA LeaderOTC MONOGRAPH DRUG

Frequently asked questions

What is Buffered Aspirin used for?

Uses temporarily relieves minor aches and pains associated with: toothache minor pain of arthritis backache the common cold headache muscular aches premenstrual & menstrual cramps temporarily reduces fever

Who makes Buffered Aspirin?

Buffered Aspirin is listed by 1 labeler in the FDA NDC directory, including Cardinal Health 110, LLC. DBA Leader.