Buscapina

Acetaminophen, Caffeine, Pyrilamine Maleate · Tablet, Coated · Oral

Over the counter Central Nervous System Stimulant Methylxanthine

Active ingredient

Drug Facts Active ingredients (in each caplet) Acetaminophen 500 mg Caffeine 60 mg Pyrilamine maleate 15 mg

Purpose

Purpose Pain reliever Diuretic Anthistamine

Uses

Uses for the temporary relief of these symptoms associated with menstrual periods: cramps bloating water-weight gain headache backache muscle aches fatigue

Warnings

Warnings Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take: more than 6 caplets in 24 hours, which is the maximum daily amount for this product with other drugs containing acetaminophen 3 or more alcoholic drinks every day while using this product Allergy alert: acetaminophen may cause severe skin or severe allergic reactions. Symptoms may include: skin reddening blisters rash hives facial swelling asthma (wheezing) shock If a skin or general allergic reaction occurs, stop use and seek medical help right away. Do not use with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist if you have ever had an allergic reaction to this product or any of its ingredients Ask a doctor before use if you have liver disease glaucoma difficulty in urination due to enlargement of the prostate gland a breathing problem such as emphysema or chronic bronchitis Ask a doctoror pharmacist before use if you are taking the blood thinning drug warfarin takin sedatives or tranquilizers When using this product you may get drowsy avoid alcoholic drinks excitability may occur, especially in children alcohol, sedatives, and tranquilizers may increase drowsiness be careful when driving a motor vehicle or operating machinery limit the use of caffeine-containing medications, foods, or beverages because too much caffeine may cause nervousness, irritability sleeplessness, and, occasionally rapid heartbeat. The recommended dose of this product contains about as much caffeine as a cup of coffee. Stop use and ask a doctor if new symptoms appear redness or swelling is present pain gets worse or lasts for more than 10 days fever gets worse or lasts for more than 3 days If pregnant or breast-feeding ask a health professional before use. Keep out of reach of children In case of overdose, get medical help or contact a Poison Control Center right away. Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.

Do not use

Do not use with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist if you have ever had an allergic reaction to this product or any of its ingredients

Ask a doctor before use

Ask a doctor before use if you have liver disease glaucoma difficulty in urination due to enlargement of the prostate gland a breathing problem such as emphysema or chronic bronchitis

Ask a doctor or pharmacist

Ask a doctoror pharmacist before use if you are taking the blood thinning drug warfarin takin sedatives or tranquilizers

When using this product

When using this product you may get drowsy avoid alcoholic drinks excitability may occur, especially in children alcohol, sedatives, and tranquilizers may increase drowsiness be careful when driving a motor vehicle or operating machinery limit the use of caffeine-containing medications, foods, or beverages because too much caffeine may cause nervousness, irritability sleeplessness, and, occasionally rapid heartbeat. The recommended dose of this product contains about as much caffeine as a cup of coffee.

Stop use and ask a doctor

Stop use and ask a doctor if new symptoms appear redness or swelling is present pain gets worse or lasts for more than 10 days fever gets worse or lasts for more than 3 days

Pregnancy or breast-feeding

If pregnant or breast-feeding ask a health professional before use.

Keep out of reach of children

Keep out of reach of children In case of overdose, get medical help or contact a Poison Control Center right away. Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.

Directions

Directions do not exceed recommended dosage Adults and children 12 years and over: take 2 caplets with water every 6 hours as needed do not exceed 6 caplets per day Children under 12 years: do not use

Inactive ingredients

Inactive ingredients colloidal silicon dioxide, hydroxy propyl methyl cellulose, microcrystalline cellulose, polyethylene glycol, corn starch, povidone, sodium starch glycolate, stearic acid, talc, titanium dioxide, lactose, purified water

Questions?

Questions or comments? Call toll free 619-600-5632 Monday through Friday 9AM - 5PM EST

Label text from the FDA structured product label by OPMX LLC (revised Mar 11, 2026). Long sections are shortened; the complete label is on DailyMed.

Active ingredients

Buscapina NDC products (5)

NDCStrength & formLabelerType
69729-130Acetaminophen 500 mg/1; Caffeine 60 mg/1; Pyrilamine Maleate 15 mg/1
Tablet, Coated
OPMX LLCOTC MONOGRAPH DRUG
69729-131Acetaminophen 500 mg/1; Caffeine 60 mg/1; Pyrilamine Maleate 15 mg/1
Tablet, Coated
OPMX LLCOTC MONOGRAPH DRUG
69729-132Pyrilamine Maleate 15 mg/1; Acetaminophen 500 mg/1; Caffeine 60 mg/1
Tablet, Coated
OPMX LLCOTC MONOGRAPH DRUG
69729-813Pyrilamine Maleate 500 mg/1; Acetaminophen 500 mg/1; Caffeine 60 mg/1
Tablet, Film Coated
OPMX LLCOTC MONOGRAPH DRUG
69729-818Pyrilamine Maleate 15 mg/1; Acetaminophen 500 mg/1; Caffeine 60 mg/1
Tablet, Coated
OPMX LLCOTC MONOGRAPH DRUG

Frequently asked questions

What is Buscapina used for?

Uses for the temporary relief of these symptoms associated with menstrual periods: cramps bloating water-weight gain headache backache muscle aches fatigue

Who makes Buscapina?

Buscapina is listed by 1 labeler in the FDA NDC directory, including OPMX LLC.