Crest

Cetylpyridinium chloride · Paste, Dentifrice · Dental, Oral

Over the counter

Active ingredient

Drug Facts Active ingredient Stannous fluoride 0.454% (0.14% w/v fluoride ion)

Purpose

Purposes Anticavity, antigingivitis, antisensitivity toothpaste

Uses

Uses aids in the prevention of cavities helps prevent gingivitis helps interfere with the harmful effects of plaque associated with gingivitis helps control plaque bacteria that contribute to the development of gingivitis builds increasing protection against painful sensitivity of the teeth to cold, heat, acids, sweets, or contact

Warnings

When using this product do not use for sensitivity longer than four weeks unless recommended by a dentist. Stop use and ask a dentist if the sensitivity problem persists or worsens. Sensitive teeth may indicate a serious problem that may need prompt care. Keep out of reach of children. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away.

When using this product

When using this product do not use for sensitivity longer than four weeks unless recommended by a dentist.

Stop use and ask a doctor

Stop use and ask a dentist if the sensitivity problem persists or worsens. Sensitive teeth may indicate a serious problem that may need prompt care.

Keep out of reach of children

Keep out of reach of children. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away.

Directions

Directions adults and children 12 yrs. & older: apply at least a 1-inch strip of the product onto a soft bristle toothbrush. Brush teeth thoroughly for at least 1 minute twice a day (morning and evening) or as recommended by a dentist. Make sure to brush all sensitive areas of the teeth do not swallow children under 12 yrs. of age: ask a dentist

Inactive ingredients

Inactive ingredients water, sorbitol, hydrated silica, sodium lauryl sulfate, sodium gluconate, flavor, carrageenan, sodium citrate, xanthan gum, zinc citrate, sodium saccharin, sodium hydroxide, stannous chloride, sucralose, titanium dioxide

Questions?

Questions? 1-800-492-7378

Label text from the FDA structured product label by The Procter & Gamble Manufacturing Company (revised Aug 27, 2026). Long sections are shortened; the complete label is on DailyMed.

Active ingredients

Crest NDC products (39)

NDCStrength & formLabelerType
58933-045Sodium Fluoride 1.5 mg/g
Paste, Dentifrice
Procter & Gamble Manufactura, S. de R.L. de C.V.OTC MONOGRAPH DRUG
58933-048Sodium Fluoride 1.5 mg/g
Paste, Dentifrice
Procter & Gamble Manufactura, S. de R.L. de C.V.OTC MONOGRAPH DRUG
58933-171Sodium Fluoride 1.5 mg/g
Paste, Dentifrice
Procter & Gamble Manufactura, S. de R.L. de C.V.OTC MONOGRAPH DRUG
58933-868Sodium Fluoride 1.5 mg/g
Paste, Dentifrice
Procter & Gamble Manufactura, S. de R.L. de C.V.OTC MONOGRAPH DRUG
58933-046Sodium Fluoride 1.5 mg/g
Paste, Dentifrice
Procter & Gamble Manufacturing Mxico, S. de R.L. de C.V.OTC MONOGRAPH DRUG
58933-047Sodium Fluoride 1.5 mg/g
Paste, Dentifrice
Procter & Gamble Manufacturing Mxico, S. de R.L. de C.V.OTC MONOGRAPH DRUG
84126-642Stannous Fluoride 1.5 mg/g
Paste, Dentifrice
The Procter & Gamble Manufacturing CompanyOTC MONOGRAPH DRUG
69423-873Stannous Fluoride 1.5 mg/g
Paste, Dentifrice
The Procter & Gamble Manufacturing CompanyOTC MONOGRAPH DRUG
69423-875Stannous Fluoride 1.5 mg/g
Paste, Dentifrice
The Procter & Gamble Manufacturing CompanyOTC MONOGRAPH DRUG
69423-877Stannous Fluoride 1.6 mg/g
Paste, Dentifrice
The Procter & Gamble Manufacturing CompanyOTC MONOGRAPH DRUG
69423-879Stannous Fluoride 1.4 mg/g
Paste, Dentifrice
The Procter & Gamble Manufacturing CompanyOTC MONOGRAPH DRUG
69423-897Sodium Fluoride 1.5 mg/g
Paste, Dentifrice
The Procter & Gamble Manufacturing CompanyOTC MONOGRAPH DRUG
84126-602Cetylpyridinium Chloride .014 g/mL
Rinse
The Procter & Gamble Manufacturing CompanyOTC MONOGRAPH DRUG
84126-618Stannous Fluoride 1.5 mg/g
Paste, Dentifrice
The Procter & Gamble Manufacturing CompanyOTC MONOGRAPH DRUG
84126-619Stannous Fluoride 1.5 mg/g
Paste, Dentifrice
The Procter & Gamble Manufacturing CompanyOTC MONOGRAPH DRUG
84126-627Stannous Fluoride 1.5 mg/g
Paste, Dentifrice
The Procter & Gamble Manufacturing CompanyOTC MONOGRAPH DRUG
84126-640Cetylpyridinium Chloride .014 g/mL
Rinse
The Procter & Gamble Manufacturing CompanyOTC MONOGRAPH DRUG
84126-641Stannous Fluoride 1.5 mg/g
Paste, Dentifrice
The Procter & Gamble Manufacturing CompanyOTC MONOGRAPH DRUG
69423-861Stannous Fluoride 1.4 mg/g
Paste, Dentifrice
The Procter & Gamble Manufacturing CompanyOTC MONOGRAPH DRUG
84126-643Stannous Fluoride 1.5 mg/g
Paste, Dentifrice
The Procter & Gamble Manufacturing CompanyOTC MONOGRAPH DRUG
84126-657Stannous Fluoride 1.4 mg/g
Paste, Dentifrice
The Procter & Gamble Manufacturing CompanyOTC MONOGRAPH DRUG
84126-658Sodium Fluoride 1.5 mg/g
Paste, Dentifrice
The Procter & Gamble Manufacturing CompanyOTC MONOGRAPH DRUG
84126-659Sodium Fluoride 1.5 mg/g
Paste, Dentifrice
The Procter & Gamble Manufacturing CompanyOTC MONOGRAPH DRUG
69423-869Stannous Fluoride 1.6 mg/g
Paste, Dentifrice
The Procter & Gamble Manufacturing CompanyOTC MONOGRAPH DRUG
69423-868Stannous Fluoride 1.6 mg/g
Paste, Dentifrice
The Procter & Gamble Manufacturing CompanyOTC MONOGRAPH DRUG
69423-867Stannous Fluoride 1.6 mg/g
Paste, Dentifrice
The Procter & Gamble Manufacturing CompanyOTC MONOGRAPH DRUG
37000-171Sodium Fluoride 1.5 mg/g
Paste, Dentifrice
The Procter & Gamble Manufacturing CompanyOTC MONOGRAPH DRUG
69423-860Stannous Fluoride 1.4 mg/g
Paste, Dentifrice
The Procter & Gamble Manufacturing CompanyOTC MONOGRAPH DRUG
69423-857Stannous Fluoride 1.4 mg/g
Paste, Dentifrice
The Procter & Gamble Manufacturing CompanyOTC MONOGRAPH DRUG
69423-852Sodium Fluoride 1.5 mg/g
Paste, Dentifrice
The Procter & Gamble Manufacturing CompanyOTC MONOGRAPH DRUG
69423-787Sodium Fluoride 1.6 mg/g
Paste, Dentifrice
The Procter & Gamble Manufacturing CompanyOTC MONOGRAPH DRUG
69423-786Stannous Fluoride 1.5 mg/g
Paste, Dentifrice
The Procter & Gamble Manufacturing CompanyOTC MONOGRAPH DRUG
69423-784Stannous Fluoride 1.5 mg/g
Paste, Dentifrice
The Procter & Gamble Manufacturing CompanyOTC MONOGRAPH DRUG
69423-783Stannous Fluoride 1.5 mg/g
Paste, Dentifrice
The Procter & Gamble Manufacturing CompanyOTC MONOGRAPH DRUG
69423-782Stannous Fluoride 1.5 mg/g
Paste, Dentifrice
The Procter & Gamble Manufacturing CompanyOTC MONOGRAPH DRUG
69423-781Stannous Fluoride 1.5 mg/g
Paste, Dentifrice
The Procter & Gamble Manufacturing CompanyOTC MONOGRAPH DRUG
37000-868Sodium Fluoride 1.5 mg/g
Paste, Dentifrice
The Procter & Gamble Manufacturing CompanyOTC MONOGRAPH DRUG
37000-576Cetylpyridinium Chloride .014 g/mL
Rinse
The Procter & Gamble Manufacturing CompanyOTC MONOGRAPH DRUG
37000-174Sodium Fluoride 1.5 mg/g
Paste, Dentifrice
The Procter & Gamble Manufacturing CompanyOTC MONOGRAPH DRUG

Frequently asked questions

What is Crest used for?

Uses aids in the prevention of cavities helps prevent gingivitis helps interfere with the harmful effects of plaque associated with gingivitis helps control plaque bacteria that contribute to the development of gingivitis builds increasing protection against painful sensitivity of the teeth to cold, heat, acids, sweets, or contact

Who makes Crest?

Crest is listed by 3 labelers in the FDA NDC directory, including Procter & Gamble Manufactura, S. de R.L. de C.V., Procter & Gamble Manufacturing Mxico, S. de R.L. de C.V., The Procter & Gamble Manufacturing Company.