CVS Diphenhydramine Hydrochloride
Diphenhydramine Hydrochloride · Tablet · Oral
Active ingredient
Active ingredient (in each tablet) Diphenhydramine Hydrochloride 25 mg Purpose Antihistamine
Purpose
Purpose Antihistamine
Uses
Uses temporarily relieves these symptoms due to hay fever or other upper respiratory allergies:
• runny nose
• sneezing
• itchy, watery eyes
• itching of the nose or throat
• temporarily relieves these symptoms due to the common cold:
• runny nose
• sneezing
Warnings
Warnings Do not use
• to make a child sleepy
• with any other product containing diphenhydramine, even one used on skin Ask a doctor before use if you have
• a breathing problem such as emphysema or chronic bronchitis
• glaucoma
• trouble urinating due to an enlarged prostate gland Ask a doctor or pharmacist before use if you are taking sedatives or tranquilizers When using this product marked drowsiness may occur avoid alcoholic drinks alcohol, sedatives and tranquilizers may increase drowsiness be careful when driving a motor vehicle or operating machinery excitability may occur, especially in children If pregnant or breast-feeding, ask a health professional before use Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222)
Do not use
Do not use
• to make a child sleepy
• with any other product containing diphenhydramine, even one used on skin
Ask a doctor before use
Ask a doctor before use if you have
• a breathing problem such as emphysema or chronic bronchitis
• glaucoma
• trouble urinating due to an enlarged prostate gland
Ask a doctor or pharmacist
Ask a doctor or pharmacist before use if you are taking sedatives or tranquilizers
When using this product
When using this product marked drowsiness may occur avoid alcoholic drinks alcohol, sedatives and tranquilizers may increase drowsiness be careful when driving a motor vehicle or operating machinery excitability may occur, especially in children
Pregnancy or breast-feeding
If pregnant or breast-feeding, ask a health professional before use
Keep out of reach of children
Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222)
Directions
Directions take every 4 to 6 hours or as directed by a doctor do not take more than 6 doses in 24 hours adults and children 12 years and over 1 to 2 tablets children 6 to under 12 years 1 tablet children under 6 years do not use
Inactive ingredients
Inactive ingredients colloidal silicon dioxide, croscarmellose sodium, dicalcium phosphate, D&C Red #27 Al lake, lecithin, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polyvinyl alcohol, talc, titanium dioxide.
Questions?
Questions or comments? Call 1-800-SHOP CVS
Label text from the FDA structured product label by CVS Pharmacy (revised Oct 2, 2025). Long sections are shortened; the complete label is on DailyMed.
Active ingredients
- Diphenhydramine Hydrochloride in 2 products
CVS Diphenhydramine Hydrochloride NDC products (2)
| NDC | Strength & form | Labeler | Type |
|---|---|---|---|
| 51316-186 | Diphenhydramine Hydrochloride 25 mg/1 Tablet | CVS Pharmacy | OTC MONOGRAPH DRUG |
| 51316-191 | Diphenhydramine Hydrochloride 25 mg/1 Tablet | CVS Pharmacy | OTC MONOGRAPH DRUG |
Frequently asked questions
What is CVS Diphenhydramine Hydrochloride used for?
Uses temporarily relieves these symptoms due to hay fever or other upper respiratory allergies: • runny nose • sneezing • itchy, watery eyes • itching of the nose or throat • temporarily relieves these symptoms due to the common cold: • runny nose • sneezing
Who makes CVS Diphenhydramine Hydrochloride?
CVS Diphenhydramine Hydrochloride is listed by 1 labeler in the FDA NDC directory, including CVS Pharmacy.