CVS Itch Relief

Pramoxine Hydrochloride, Zinc Acetate · Spray · Topical

Over the counter Copper Absorption Inhibitor Histamine-1 Receptor Antagonist

Active ingredient

Active ingredients Pramoxine HCl 1% Zinc Acetate 0.1%

Purpose

Purposes Topical analgesic Skin protectant

Uses

Uses temporarily relieves pain and itching associated with: rashes due to posion ivy, poison oak or poison sumac insect bites minor skin irritation minor cuts dries the oozing and weeping of poison ivy, poison oak and poison sumac

Warnings

Warnings For external use only Flammable: Do not use while smoking or near heat or flame Do not apply to wounds or damaged, broken or irritated skin. do not allow contact with eyes or mucous membranes. When using this product keep out of eyes (Rinse with water to remove) do not puncture or incinerate. Contents under pressure. do not store at temperatures above 120 degrees F. Stop use and ask a doctor if condition worsens or does not improve within 7 days symptoms persist for more than 7 days or clear up and occur again within a few days If pregnant or breast-feeding ask a health professional before use. Keep out of reach of children and pets. If swallowed, get medical help or contact a Poison Control Center right away.

Do not use

Do not apply to wounds or damaged, broken or irritated skin. do not allow contact with eyes or mucous membranes.

When using this product

When using this product keep out of eyes (Rinse with water to remove) do not puncture or incinerate. Contents under pressure. do not store at temperatures above 120 degrees F.

Stop use and ask a doctor

Stop use and ask a doctor if condition worsens or does not improve within 7 days symptoms persist for more than 7 days or clear up and occur again within a few days

Pregnancy or breast-feeding

If pregnant or breast-feeding ask a health professional before use.

Keep out of reach of children

Keep out of reach of children and pets. If swallowed, get medical help or contact a Poison Control Center right away.

Directions

Directions shake well. Adults and children 2 years of age and older: apply to affected area not more than 3 to 4 times daily to apply to face, spray into palm of hand and gently apply children under 2 years of age: consult a doctor Store at 68° to 77° F (20° to 25° C).

Inactive ingredients

Inactive ingredients Avena Sativa (Oat) Meal Extract, Camphor, Citric Acid, Deionized Water, Diazolidinyl Urea, Glycerin, Hydroxypropyl Methylcellulose, Polysorbate 40, Propylene Glycol, SD Alcohol 40-B, Sodium Citrate

Label text from the FDA structured product label by CVS Pharmacy (revised Aug 7, 2026). Long sections are shortened; the complete label is on DailyMed.

Active ingredients

CVS Itch Relief NDC products (3)

NDCStrength & formLabelerType
69842-952Zinc Acetate .1 g/100mL; Diphenhydramine Hydrochloride 2 g/100mL
Spray
CVSOTC MONOGRAPH DRUG
51316-624Pramoxine Hydrochloride 10 mg/g; Zinc Acetate 1 mg/g
Spray
CVS PharmacyOTC MONOGRAPH DRUG
69842-400Pramoxine Hydrochloride 10 mg/mL; Zinc Acetate 1 mg/mL
Lotion
CVS PharmacyOTC MONOGRAPH DRUG

Frequently asked questions

What is CVS Itch Relief used for?

Uses temporarily relieves pain and itching associated with: rashes due to posion ivy, poison oak or poison sumac insect bites minor skin irritation minor cuts dries the oozing and weeping of poison ivy, poison oak and poison sumac

Who makes CVS Itch Relief?

CVS Itch Relief is listed by 2 labelers in the FDA NDC directory, including CVS, CVS Pharmacy.