CVS Nighttime Childrens

Chlorpheniramine maleate and Dextromethorphan Hydrobromide · Solution · Oral

Over the counter Histamine-1 Receptor Antagonist Sigma-1 Agonist Uncompetitive N-methyl-D-aspartate Receptor Antagonist

Active ingredient

Active ingredients (in each 15 mL) Purpose Chlorpheniramine maleate 2 mg Antihistamine Dextromethorphan HBr 15 mg Cough suppressant

Purpose

Active ingredients (in each 15 mL) Purpose Chlorpheniramine maleate 2 mg Antihistamine Dextromethorphan HBr 15 mg Cough suppressant

Uses

Uses temporarily relieves cold symptoms: ▪ cough due to minor throat & bronchial irritation ▪ sneezing ▪ runny nose

Warnings

Warnings Do not use ▪ if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. ▪ to make a child sleepy Ask a doctor before use if you have ▪ glaucoma ▪ cough that occurs with too much phlegm (mucus) ▪ a breathing problem or chronic cough that lasts or as occurs with smoking, asthma, chronic bronchitis or emphysema ▪ trouble urinating due to enlarged prostate gland Ask a doctor or pharmacist before use if you are taking sedatives or tranquilizers. When using this product ▪ excitability may occur, especially in children ▪ marked drowsiness may occur ▪ avoid alcoholic drinks ▪ be careful when driving a motor vehicle or operating machinery ▪ alcohol, sedatives, & tranquilizers may increase drowsiness Stop use and ask a doctor if ▪ cough persists more than 1 week, tends to recur or is accompanied by fever, rash, or persistent headache. These could be signs of a serious condition. If pregnant or breast-feeding , ask a health professional before use. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away at 1-800-222-1222.

Do not use

Do not use ▪ if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. ▪ to make a child sleepy

Ask a doctor before use

Ask a doctor before use if you have ▪ glaucoma ▪ cough that occurs with too much phlegm (mucus) ▪ a breathing problem or chronic cough that lasts or as occurs with smoking, asthma, chronic bronchitis or emphysema ▪ trouble urinating due to enlarged prostate gland

Ask a doctor or pharmacist

Ask a doctor or pharmacist before use if you are taking sedatives or tranquilizers.

When using this product

When using this product ▪ excitability may occur, especially in children ▪ marked drowsiness may occur ▪ avoid alcoholic drinks ▪ be careful when driving a motor vehicle or operating machinery ▪ alcohol, sedatives, & tranquilizers may increase drowsiness

Stop use and ask a doctor

Stop use and ask a doctor if ▪ cough persists more than 1 week, tends to recur or is accompanied by fever, rash, or persistent headache. These could be signs of a serious condition.

Pregnancy or breast-feeding

If pregnant or breast-feeding , ask a health professional before use.

Keep out of reach of children

Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away at 1-800-222-1222.

Directions

Directions ▪ take only as directed ▪ do not exceed 4 doses per 24 hrs. ▪ only use the dose cup provided adults & children 12 yrs & over 30 mL every 6 hrs. children 6 to under 12 yrs 15 mL every 6 hrs. children 4 to under 6 yrs do not use unless directed by a doctor children under 4 yrs do not use

Other information

Other information ▪ each 15 mL contains: potassium 5 mg, sodium 5 mg ▪ sugar free ▪ aspirin free ▪ store at room temperature

Inactive ingredients

Inactive ingredients anhydrous citric acid, FD&C Red No. 40, flavor, potassium citrate, potassium sorbate, propylene glycol, purified water, sodium benzoate, sorbitol, sucrose

Questions?

Questions or comments? 1-866-467-2748

Label text from the FDA structured product label by CVS PHARMACY (revised Aug 19, 2026). Long sections are shortened; the complete label is on DailyMed.

Active ingredients

CVS Nighttime Childrens NDC products (1)

NDCStrength & formLabelerType
51316-752Chlorpheniramine Maleate 2 mg/15mL; Dextromethorphan Hydrobromide 15 mg/15mL
Solution
CVS PHARMACYOTC MONOGRAPH DRUG

Frequently asked questions

What is CVS Nighttime Childrens used for?

Uses temporarily relieves cold symptoms: ▪ cough due to minor throat & bronchial irritation ▪ sneezing ▪ runny nose

Who makes CVS Nighttime Childrens?

CVS Nighttime Childrens is listed by 1 labeler in the FDA NDC directory, including CVS PHARMACY.