Defense Refresh (Re)Setting Mist SPF 40

Avobenzone, Homosalate , Octisalate, Octocrylene · Liquid · Topical

Over the counter

Active ingredient

Avobenzone 2.9%..............Sunscreen Homosalate 9.8%.............Sunscreen Octisalate 4.9%..................Sunscreen Octocrylene 9.5%...............Sunscreen

Purpose

Helps prevent sunburn. If used as directed with other sun protection measures (see Directions), decreases the risk of skin cancer and early skin aging caused by the sun

Uses

Stop use and ask a doctor if rash occurs.

Warnings

For external use only. Do not use on damaged or broken skin. When using this product keep out of eyes. Rinse with water to remove.

Keep out of reach of children

Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

Directions

· Shake well then apply generously and evenly 15 minutes before sun exposure. · reapply: · after 40 minutes of swimming or sweating · immediately after towel drying · at least every 2 hours · Sun Protection Measures: spending time in the sun increases your risk of skin cancer and early skin aging. To decrease this risk, regularly use a sunscreen with a Broad Spectrum SPF value of 15 or higher and other sun protection measures including: · Limit time in the sun, especially from 10 a.m. - 2 p.m. · Wear long-sleeved shirts, pants, hats, and sunglasses · Children under 6 months: Ask a doctor

Inactive ingredients

Alcohol Denat., Bisabolol, Brassica Campestris/Aleurites Fordi Oil Copolymer, Butyloctyl Salicylate, Caprylic/Capric Triglyceride, Capryloyl Glycerin/Sebacic Acid Copolymer, Dicaprylyl Carbonate, Diethylhexyl Syringylidenemalonate, Diheptyl Succinate, Diisooctyl Succinate, Ethyl Ferulate, Isododecane, Lauroyl Lysine, Mentha Piperita (Peppermint) Oil, Mentha Viridis (Spearmint) Leaf Oil, Nylon-12, PVP, Rosmarinus Officinalis (Rosemary) Leaf Oil, Silica Caprylyl Silylate

Label text from the FDA structured product label by Supergoop LLC (revised Jan 9, 2026). Long sections are shortened; the complete label is on DailyMed.

Active ingredients

Defense Refresh (Re)Setting Mist SPF 40 NDC products (1)

NDCStrength & formLabelerType
75936-354Homosalate 9.8 g/100mL; Avobenzone 2.9 g/100mL; Octisalate 4.9 g/100mL; Octocrylene 9.5 g/100mL
Liquid
Supergoop LLCOTC MONOGRAPH DRUG

Frequently asked questions

What is Defense Refresh (Re)Setting Mist SPF 40 used for?

Stop use and ask a doctor if rash occurs.

Who makes Defense Refresh (Re)Setting Mist SPF 40?

Defense Refresh (Re)Setting Mist SPF 40 is listed by 1 labeler in the FDA NDC directory, including Supergoop LLC.