Differin Epiduo
Adapalene and Benzoyl Peroxide · Gel · Topical
Active ingredient
Drug Facts Active ingredient Adapalene 0.1% (retinoid)* *read consumer information leaflet Benzoyl Peroxide 2.5%
Purpose
Purpose Acne treatment Acne treatment
Uses
Use For the treatment of acne
Warnings
Warnings For external use only
Do not use
Do not use on damaged skin (cuts, abrasions, eczema, sunburn) if you are allergic to adapalene or any of the ingredients in this product. If you have very sensitive skin If you are sensitive to benzoyl peroxide
Ask a doctor or pharmacist
Ask a doctor or pharmacist before use if you use any other acne medications have any other skin or medical conditions If pregnant or breast-feeding, ask a doctor before use.
When using this product
When using this product limit sun exposure, including light from tanning beds, and use sunscreen when going outdoors do not wax to remove hair in areas where the product has been applied avoid contact with hair and dyed fabrics, which may be bleached by this product during the early weeks of use, your acne may appear to worsen before it improves (this is normal) irritation (redness, itching, dryness, burning, peeling or possible swelling) is more likely to occur: in the first four weeks of use if using more than one topical acne medication at a time If irritation occurs, it may be reduced: by using the product less frequently by using moisturizer by using only one topical acne medication at a time it may take up to 3 months of once daily use to see results avoid product contact with eyes, lips, and mouth. If contact occurs, immediately flush the area with water. wash hands after use
Stop use and ask a doctor
Stop use and ask doctor if you become pregnant, or are planning to become pregnant, while using the product you have symptoms of an allergic reaction (such as itching, rash, hives, swelling of the lips, eyelids, and shortness of breath) irritation gets worse you see no improvement after 3 months of once daily use Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.
Keep out of reach of children
Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.
Directions
Directions Adults and children 12 years of age and older: use once daily clean the skin gently and pat dry before applying the product cover the entire affected area with a thin layer. For example, if your acne is on the face, apply the product to the entire face. applying more than directed will not provide faster or better results, but may worsen skin irritation. if going outside, apply sunscreen after using this product. If irritation or sensitivity develops, stop use of both products and ask a doctor. Children under 12 years of age: do not use Other information store at 20°C to 25°C (68°F to 77°F) protect from freezing protect from light and keep away from heat
Inactive ingredients
Inactive Ingredients acrylamide/sodium acryloyldimethyltaurate copolymer, docusate sodium, edetate disodium, glycerin, isohexadecane, poloxamer 124, polysorbate 80, propylene glycol, purified water, and sorbitan oleate
Questions?
Questions? 1-866-735-4137
Label text from the FDA structured product label by Galderma Laboratories, L.P. (revised May 20, 2026). Long sections are shortened; the complete label is on DailyMed.
Active ingredients
- Adapalene in 1 product
- Benzoyl Peroxide in 1 product
Differin Epiduo NDC products (1)
| NDC | Strength & form | Labeler | Type |
|---|---|---|---|
| 0299-4908 | Adapalene 1 mg/g; Benzoyl Peroxide 25 mg/g Gel | Galderma Laboratories, L.P. | NDA |
Frequently asked questions
What is Differin Epiduo used for?
Use For the treatment of acne
Who makes Differin Epiduo?
Differin Epiduo is listed by 1 labeler in the FDA NDC directory, including Galderma Laboratories, L.P..