Extra Strength Itch Relief
Diphenhydramine HCl and Zinc Acetate · Spray · Topical
Active ingredient
Active ingredients Diphenhydramine HCl 2.0%, Zinc acetate 0.1%
Purpose
Purpose External analgesic Skin protectant
Uses
Uses for the temporary relief of pain and itching associated with: minor burns sunburn minor cuts scrapes insect bites minor skin irritations rashes due to poison ivy, poison oak and poison sumac dries the oozing and weeping of poison ivy, poison oak and poison sumac
Warnings
Warnings For external use only. Flammable: Keep away from fire or flame. Do not puncture or incinerate. Contents under pressure. Do not store at temperatures above 120ºF. Intentional misuse by deliberately concentrating and inhaling contents can be harmful or fatal. Do not use on large areas of the body with any other product containing diphenhydramine, even one taken by mouth Ask a doctor before use on chicken pox on measles When using this product avoid contact with eyes Stop use and ask doctor if conditions worsens symptoms last more than 7 days or clear up and occur again within a few days Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.
Do not use
Do not use on large areas of the body with any other product containing diphenhydramine, even one taken by mouth
Ask a doctor before use
Ask a doctor before use on chicken pox on measles
When using this product
When using this product avoid contact with eyes
Stop use and ask a doctor
Stop use and ask doctor if conditions worsens symptoms last more than 7 days or clear up and occur again within a few days
Keep out of reach of children
Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.
Directions
Directions do not use more often than directed adults and children 2 years of age and older: apply to affected area not more than 3 to 4 times daily children under 2 years of age: ask a doctor
Inactive ingredients
Inactive ingredients aloe barbadensis leaf juice, glycerin, purified water, SD alcohol 40-B, tromethamine
Questions?
Questions? call 1-866-964-0939
Label text from the FDA structured product label by Chain Drug Marketing Association Inc (revised Nov 6, 2025). Long sections are shortened; the complete label is on DailyMed.
Active ingredients
- Diphenhydramine Hydrochloride in 2 products
- Zinc Acetate in 2 products
Extra Strength Itch Relief NDC products (2)
| NDC | Strength & form | Labeler | Type |
|---|---|---|---|
| 83324-302 | Diphenhydramine Hydrochloride 20 mg/g; Zinc Acetate 1 mg/g Spray | Chain Drug Marketing Association Inc | OTC MONOGRAPH DRUG |
| 79481-0598 | Diphenhydramine Hydrochloride 20 mg/g; Zinc Acetate 1 mg/g Spray | Meijer Distribution Inc | OTC MONOGRAPH DRUG |
Frequently asked questions
What is Extra Strength Itch Relief used for?
Uses for the temporary relief of pain and itching associated with: minor burns sunburn minor cuts scrapes insect bites minor skin irritations rashes due to poison ivy, poison oak and poison sumac dries the oozing and weeping of poison ivy, poison oak and poison sumac
Who makes Extra Strength Itch Relief?
Extra Strength Itch Relief is listed by 2 labelers in the FDA NDC directory, including Chain Drug Marketing Association Inc, Meijer Distribution Inc.