Extra Strength Pain Reliever PM

Acetaminophen, Diphenhydramine HCl · Tablet · Oral

Over the counter Histamine-1 Receptor Antagonist

Active ingredient

Active ingredients (in each caplet) Purpose Acetaminophen 500mg Pain reliever Diphenhydramine HCl 25mg Nighttime Sleep aid

Purpose

Active ingredients (in each caplet) Purpose Acetaminophen 500mg Pain reliever Diphenhydramine HCl 25mg Nighttime Sleep aid

Uses

Uses for the temporary relief of occasional headaches and minor aches and pains with accompanying sleeplessness

Warnings

Warnings Liver warning This product contains acetaminophen. Severe liver damage may occur with this product if you take more than 4,000 mg of acetaminophen in 24 hours with other drugs containing acetaminophen 3 or more alcoholic drinks every day while you are using this product Allergy alert Acetaminophen may cause severe skin reactions. Symptoms may include: skin reddening blisters rash If a skin reaction occurs, stop use and seek medical help right away. Do not use with other products containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist in children under 12 years of age with any other products containing diphenhydramine, even one used on skin if you are allergic to acetaminophen or any of the inactive ingredients in this product Ask a doctor before use if you have liver disease breathing problems such as emphysema or chronic bronchitis trouble urinating due to an enlargement of the prostate gland glaucoma Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin taking sedatives or tranquilizers When using this product drowsiness will occur avoid alcoholic drinks do not drive a motor vehicle or operate machinery. Stop use and ask a doctor if sleeplessness persists continuously for more than 2 weeks. Insomnia may be a symptom of a serious underlying medical illness pain gets worse or lasts for more than 10 days fever gets worse or lasts more than 3 days new symptoms occur redness or swelling is present These could be signs of a serious condition. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. Overdose warning Taking more than the directed dose (overdose) may cause liver damage. In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222). Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.

Do not use

Do not use with other products containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist in children under 12 years of age with any other products containing diphenhydramine, even one used on skin if you are allergic to acetaminophen or any of the inactive ingredients in this product

Ask a doctor before use

Ask a doctor before use if you have liver disease breathing problems such as emphysema or chronic bronchitis trouble urinating due to an enlargement of the prostate gland glaucoma

Ask a doctor or pharmacist

Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin taking sedatives or tranquilizers

When using this product

When using this product drowsiness will occur avoid alcoholic drinks do not drive a motor vehicle or operate machinery.

Stop use and ask a doctor

Stop use and ask a doctor if sleeplessness persists continuously for more than 2 weeks. Insomnia may be a symptom of a serious underlying medical illness pain gets worse or lasts for more than 10 days fever gets worse or lasts more than 3 days new symptoms occur redness or swelling is present These could be signs of a serious condition.

Pregnancy or breast-feeding

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children

Keep out of reach of children.

Directions

Directions do not take more than directed (see Overdose warning ) adults and children 12 years of age and over: take 2 caplets at bedtime or as directed by a doctor do not take more than 2 caplets in a 24 hour period children under 12 years of age: do not use this adult product in children under 12 years of age. This will provide more than the recommended dose (overdose) and may cause liver damage

Other information

Other information each caplet contains: magnesium 0.05 mg store between 20°-25°C (68°-77°F) see end panel for lot number and expiration

Inactive ingredients

Inactive ingredients FD&C blue # 1, FD&C blue # 2, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol-400, povidone, pregelatinized starch, stearic acid, titanium dioxide

Questions?

Questions or comments? 1-888-287-1915

Label text from the FDA structured product label by WALMART INC. (revised Jan 27, 2026). Long sections are shortened; the complete label is on DailyMed.

Active ingredients

Extra Strength Pain Reliever PM NDC products (3)

NDCStrength & formLabelerType
62936-0224Acetaminophen 500 mg/1; Diphenhydramine Hydrochloride 25 mg/1
Tablet
INGLES MARKETS, INC.OTC MONOGRAPH DRUG
0363-9085Acetaminophen 500 mg/1; Diphenhydramine Hydrochloride 25 mg/1
Tablet
WALGREENS CO.OTC MONOGRAPH DRUG
79903-053Acetaminophen 500 mg/1; Diphenhydramine Hydrochloride 25 mg/1
Tablet
WALMART INC.OTC MONOGRAPH DRUG

Frequently asked questions

What is Extra Strength Pain Reliever PM used for?

Uses for the temporary relief of occasional headaches and minor aches and pains with accompanying sleeplessness

Who makes Extra Strength Pain Reliever PM?

Extra Strength Pain Reliever PM is listed by 3 labelers in the FDA NDC directory, including INGLES MARKETS, INC., WALGREENS CO., WALMART INC..