EZ Nite Sleep
Diphenhydramine HCl · Liquid · Oral
Active ingredient
Active ingredient (in each 30 mL) Diphenhydramine HCl 50 mg
Purpose
Purpose Nighttime sleep-aid
Uses
Uses for the relief of occasional sleeplessness reduces time to fall asleep if you have difficulty falling asleep
Warnings
Warnings Do not use with any other product containing diphenhydramine, even one used on skin for children under 12 years of age Ask a doctor before use if you have breathing problem such as asthma emphysema or chronic bronchitis glaucoma trouble urinating due to an enlarged prostate gland Ask a doctor or pharmacist before use if you are taking sedatives or tranquilizers. When using this product avoid alcoholic beverages. Stop use and ask a doctor if sleeplessness persists continuously for more than 2 weeks. Insomnia may be a symptom of serious underlying medical illness. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. Overdose warning: In case of overdose, get medical help or contact a Poison Control Center (1800-222-1222) right away.
Do not use
Do not use with any other product containing diphenhydramine, even one used on skin for children under 12 years of age
Ask a doctor before use
Ask a doctor before use if you have breathing problem such as asthma emphysema or chronic bronchitis glaucoma trouble urinating due to an enlarged prostate gland
Ask a doctor or pharmacist
Ask a doctor or pharmacist before use if you are taking sedatives or tranquilizers.
When using this product
When using this product avoid alcoholic beverages.
Stop use and ask a doctor
Stop use and ask a doctor if sleeplessness persists continuously for more than 2 weeks. Insomnia may be a symptom of serious underlying medical illness.
Pregnancy or breast-feeding
If pregnant or breast-feeding, ask a health professional before use.
Keep out of reach of children
Keep out of reach of children. Overdose warning: In case of overdose, get medical help or contact a Poison Control Center (1800-222-1222) right away.
Directions
Directions take only one dose per day (24 hours) mL= milliliter keep dosing cup with product measure only with dosing cup provided. Do not use any other dosing device adults and children 12 years and over one dose=30mL at bedtime if needed, or as directed by a doctor children under 12 years do not use
Inactive ingredients
Inactive ingredients citric acid, ethyl alcohol, FD&C blue #1, FD&C red #40, flavor, high fructose corn syrup, polyoxyl 40 stearate, propylene glycol, purified water, saccharin sodium, sodium benzoate, sodium citrate dihydrate
Questions?
Questions or comments?
Label text from the FDA structured product label by Safeway, Inc. (revised Jul 7, 2025). Long sections are shortened; the complete label is on DailyMed.
Active ingredients
- Diphenhydramine Hydrochloride in 2 products
EZ Nite Sleep NDC products (2)
| NDC | Strength & form | Labeler | Type |
|---|---|---|---|
| 41226-613 | Diphenhydramine Hydrochloride 25 mg/1 Capsule, Liquid Filled | KROGER COMPANY | OTC MONOGRAPH DRUG |
| 21130-014 | Diphenhydramine Hydrochloride 50 mg/30mL Liquid | Safeway, Inc. | OTC MONOGRAPH DRUG |
Frequently asked questions
What is EZ Nite Sleep used for?
Uses for the relief of occasional sleeplessness reduces time to fall asleep if you have difficulty falling asleep
Who makes EZ Nite Sleep?
EZ Nite Sleep is listed by 2 labelers in the FDA NDC directory, including KROGER COMPANY, Safeway, Inc..