Goodmeds Extra Strength Pain Relief PM

Acetaminophen, Diphenhydramine Hydrochloride · Tablet · Oral

Over the counter Histamine-1 Receptor Antagonist

Active ingredient

Active ingredients (in each caplet) Acetaminophen 500 mg Diphenhydramine HCl 25 mg Purpose Pain reliever Nighttime sleep aid

Purpose

Purpose Pain reliever Nighttime sleep aid

Uses

Uses temporary relief of occasional headaches and minor aches and pains with accompanying sleeplessness

Warnings

Warnings Liver warning : This product contains acetaminophen. Severe liver damage may occur if you take more than 4,000 mg of acetaminophen in 24 hours with other drugs containing acetaminophen 3 or more alcoholic drinks every day while using this product Allergy alert : Acetaminophen may cause severe skin reactions. Symptoms may include: ■ skin reddening ■ blisters ■ rash If a skin reaction occurs, stop use and seek medical help right away. Do not use with other products containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist with any product containing diphenhydramine, even one used on skin in children under 12 years of age if you have ever had an allergic reaction to this product or any of its ingredients Ask a doctor before use if you have liver disease breathing problems such as emphysema or chronic bronchitis trouble urinating due to an enlarged prostate gland glaucoma Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin taking sedatives or tranquilizers When using this product drowsiness will occur avoid alcoholic drinks do not drive a motor vehicle or operate machinery. Stop use and ask a doctor if sleeplessness persists continuously for more than 2 weeks. Insomnia may be a symptom of a serious underlying medical illness pain gets worse or lasts for more than 10 days fever gets worse or lasts more than 3 days redness or swelling is present new symptoms occur These could be signs of a serious condition If pregnant or breast-feeding ask a health professional before use. Keep out of reach of children. Overdose warning : Taking more than the recommended dose (overdose) may cause liver damage. In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222) Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.

Do not use

Do not use with other products containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist with any product containing diphenhydramine, even one used on skin in children under 12 years of age if you have ever had an allergic reaction to this product or any of its ingredients

Ask a doctor before use

Ask a doctor before use if you have liver disease breathing problems such as emphysema or chronic bronchitis trouble urinating due to an enlarged prostate gland glaucoma

Ask a doctor or pharmacist

Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin taking sedatives or tranquilizers

When using this product

When using this product drowsiness will occur avoid alcoholic drinks do not drive a motor vehicle or operate machinery.

Stop use and ask a doctor

Stop use and ask a doctor if sleeplessness persists continuously for more than 2 weeks. Insomnia may be a symptom of a serious underlying medical illness pain gets worse or lasts for more than 10 days fever gets worse or lasts more than 3 days redness or swelling is present new symptoms occur These could be signs of a serious condition

Pregnancy or breast-feeding

If pregnant or breast-feeding ask a health professional before use.

Keep out of reach of children

Keep out of reach of children. Overdose warning : Taking more than the recommended dose (overdose) may cause liver damage. In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222) Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.

Directions

Directions do not take more than recommended (see overdose warning) adults and children 12 years and over take 2 caplets at bedtime do not take more than 2 caplets of this product in 24 hours children under 12 years do not use

Inactive ingredients

Inactive ingredients FD&C Blue # 1, FD&C Blue # 2, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, pregelatinized starch, povidone K-30, purified water, stearic acid, titanium dioxide

Questions?

Questions or comments? contact 1-908-242-6108 Mon-Fri 8:00 AM to 5:00 PM EST

Label text from the FDA structured product label by Cabinet Health P.B.C. (revised Jan 6, 2026). Long sections are shortened; the complete label is on DailyMed.

Active ingredients

Goodmeds Extra Strength Pain Relief PM NDC products (1)

NDCStrength & formLabelerType
82725-4124Acetaminophen 500 mg/1; Diphenhydramine Hydrochloride 25 mg/1
Tablet
Cabinet Health P.B.C.OTC MONOGRAPH DRUG

Frequently asked questions

What is Goodmeds Extra Strength Pain Relief PM used for?

Uses temporary relief of occasional headaches and minor aches and pains with accompanying sleeplessness

Who makes Goodmeds Extra Strength Pain Relief PM?

Goodmeds Extra Strength Pain Relief PM is listed by 1 labeler in the FDA NDC directory, including Cabinet Health P.B.C..