Guaifenesin and Dextromethorphan Hydrobromide

Syrup · Oral

Over the counter Expectorant Sigma-1 Agonist Uncompetitive N-methyl-D-aspartate Receptor Antagonist

Active ingredient

Active ingredients (in each extended-release tablet) Purposes Dextromethorphan HBr 60 mg Cough suppressant Guaifenesin 1200 mg Expectorant

Purpose

Active ingredients (in each extended-release tablet) Purposes Dextromethorphan HBr 60 mg Cough suppressant Guaifenesin 1200 mg Expectorant

Uses

Uses helps loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus and make coughs more productive temporarily relieves: cough due to minor throat and bronchial irritation as may occur with the common cold or inhaled irritants the intensity of coughing the impulse to cough to help you get to sleep

Warnings

Warnings Do not use for children under 12 years of age if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. Ask a doctor before use if you have persistent or chronic cough such as occurs with smoking, asthma, chronic bronchitis, or emphysema cough accompanied by too much phlegm (mucus) When using this product do not use more than directed Stop use and ask a doctor if cough lasts more than 7 days, comes back, or occurs with fever, rash, or persistent headache. These could be signs of a serious illness. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222).

Do not use

Do not use for children under 12 years of age if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.

Ask a doctor before use

Ask a doctor before use if you have persistent or chronic cough such as occurs with smoking, asthma, chronic bronchitis, or emphysema cough accompanied by too much phlegm (mucus)

When using this product

When using this product do not use more than directed

Stop use and ask a doctor

Stop use and ask a doctor if cough lasts more than 7 days, comes back, or occurs with fever, rash, or persistent headache. These could be signs of a serious illness.

Pregnancy or breast-feeding

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children

Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222).

Directions

Directions do not crush, chew, or break extended-release tablet take with a full glass of water this product can be administered without regard for timing of meals adults and children 12 years and older: 1 extended-release tablet every 12 hours; not more than 2 extended-release tablets in 24 hours children under 12 years of age: do not use

Other information

Other information Store between 20-25°C (68-77°F)

Inactive ingredients

Inactive ingredients carbomer homopolymer, colloidal silicon dioxide, hypromellose, magnesium stearate, maltodextrin, microcrystalline cellulose, povidone (K-30), stearic acid

Questions?

Questions? (1-800-406-7984) You may also report side effects to this phone number.

Label text from the FDA structured product label by CVS PHARMACY, INC (revised Apr 20, 2026). Long sections are shortened; the complete label is on DailyMed.

Active ingredients

Guaifenesin and Dextromethorphan Hydrobromide NDC products (5)

NDCStrength & formLabelerType
51316-600Guaifenesin 1200 mg/1; Dextromethorphan Hydrobromide 60 mg/1
Tablet, Extended Release
CVS PHARMACY, INCANDA
72162-2277Dextromethorphan Hydrobromide 10 mg/5mL; Guaifenesin 100 mg/5mL
Syrup
Bryant Ranch PrepackOTC MONOGRAPH DRUG
57631-013Guaifenesin 400 mg/1; Dextromethorphan Hydrobromide 20 mg/1
Tablet
InvaTech Pharma Solutions LLCOTC MONOGRAPH DRUG
58657-504Dextromethorphan Hydrobromide 10 mg/5mL; Guaifenesin 100 mg/5mL
Syrup
Method PharmaceuticalsOTC MONOGRAPH DRUG
58657-505Dextromethorphan Hydrobromide 10 mg/5mL; Guaifenesin 100 mg/5mL
Syrup
Method PharmaceuticalsOTC MONOGRAPH DRUG

Frequently asked questions

What is Guaifenesin and Dextromethorphan Hydrobromide used for?

Uses helps loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus and make coughs more productive temporarily relieves: cough due to minor throat and bronchial irritation as may occur with the common cold or inhaled irritants the intensity of coughing the impulse to cough to help you get to sleep

Who makes Guaifenesin and Dextromethorphan Hydrobromide?

Guaifenesin and Dextromethorphan Hydrobromide is listed by 4 labelers in the FDA NDC directory, including CVS PHARMACY, INC, Bryant Ranch Prepack, InvaTech Pharma Solutions LLC, Method Pharmaceuticals.