Iolite-S

Benzocaine · Spray · Dental

Over the counter Standardized Chemical Allergen

Active ingredient

Active Ingredient Benzocaine 20%

Purpose

Purpose Oral anesthetic

Uses

Uses For the temporary relief of occasional minor irritation and pain associated with canker sores and minor dental procedures.

Warnings

Warnings Methemoglobinemia Warning Use of this product may cause methemoglobinemia, a serious condition that must be treated promptly because it reduces the amount of oxygen carried in the blood. This can occur even if you have use this product before. Stop use and seek immediate medical attention if you or a child in your care develops: pale, gray, or blue colored skin (cyanosis) headache rapid heart rate shortness of breath dizziness or lightheadedness fatigue or lack of energy Allergy Alert Do not use this product if you have a history of allergy to local anesthetics such as procaine, butacaine, benzocaine, or other '-caine' anesthetics. Do not use this product for more than 7 days unless directed by a dentist or doctor. If sore mouth symptoms do not improve in 7 days; if irritation, pain, or redness persist or worsens, or if swelling, rash, or fever develops, see your dentist or doctor promptly. For teething In children under 2 years of age Do not use near fire or flame. Flammable. Do not exceed recommended dosage. Avoid spraying in the eyes. Keep out of reach of children. If more than used for pain is accidentially swallowed, get medical help or contact a Poison Control Center right away.

Do not use

Allergy Alert Do not use this product if you have a history of allergy to local anesthetics such as procaine, butacaine, benzocaine, or other '-caine' anesthetics. Do not use this product for more than 7 days unless directed by a dentist or doctor. If sore mouth symptoms do not improve in 7 days; if irritation, pain, or redness persist or worsens, or if swelling, rash, or fever develops, see your dentist or doctor promptly. For teething In children under 2 years of age Do not use near fire or flame. Flammable.

Stop use and ask a doctor

Methemoglobinemia Warning Use of this product may cause methemoglobinemia, a serious condition that must be treated promptly because it reduces the amount of oxygen carried in the blood. This can occur even if you have use this product before. Stop use and seek immediate medical attention if you or a child in your care develops: pale, gray, or blue colored skin (cyanosis) headache rapid heart rate shortness of breath dizziness or lightheadedness fatigue or lack of energy

Keep out of reach of children

Keep out of reach of children. If more than used for pain is accidentially swallowed, get medical help or contact a Poison Control Center right away.

Directions

Directions Shake well before use. Firmly insert extension tube into spray can valve and ensure it fits securely in the actuator opening. Position the extension tube 1-2 inches from the affected area. Press 1/2 second (press and immediately release the actuator). Adults and children 12 years of age and older: Apply to the affected area. Use up to 4 times daily or as directed by a dentist or doctor. Children under 12 years of age should be supervised in the use of this product. Children under 2 years of age: do not use.

Inactive ingredients

Inactive Ingredients Ethyl alcohol, Flavor, Isobutane (propellant), Polyethylene glycol, Propane (propellant), Saccharine sodium.

Label text from the FDA structured product label by Dharma Research, Inc. (revised Jun 14, 2025). Long sections are shortened; the complete label is on DailyMed.

Active ingredients

Iolite-S NDC products (1)

NDCStrength & formLabelerType
53045-127Benzocaine 12 g/100mL
Spray
Dharma Research, Inc.OTC MONOGRAPH DRUG

Frequently asked questions

What is Iolite-S used for?

Uses For the temporary relief of occasional minor irritation and pain associated with canker sores and minor dental procedures.

Who makes Iolite-S?

Iolite-S is listed by 1 labeler in the FDA NDC directory, including Dharma Research, Inc..