Itch Relief Gel

Diphenhydramine HCl · Gel · Topical

Over the counter Histamine-1 Receptor Antagonist

Active ingredient

Active ingredient Diphenhydramine HCL 2%

Purpose

Purpose Topical Analgesic

Uses

Directions Do not use more than directed. Adults and children 2 years of age and older: apply to affected area not more than 3 to 4 times daily.

Warnings

Warnings For external use only.

Do not use

Do not use: on large areas of the body, with any other product containing diphenhydramine, even one taken by mouth When using this product avoid contact with eyes

Ask a doctor before use

Ask a doctor before use on chicken pox, on measles Stop use and ask a doctor if condition worsens, symptoms persist for more than 7 days or clear up and occur again within a few days

Keep out of reach of children

Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

Directions

Directions Apply to affected area not more thatn 3 to 4 times daily

Other information

Other information Store at room temperature

Inactive ingredients

Inactive ingredients camphor, diazolidinyl urea, glycerin, hydroxypropyl methylcellulose, methylparaben, propylene glycol, propylparaben, purified water, SD alcohol 40-B, sodium citrate

Questions?

Questions? 1-800-925-4733

Label text from the FDA structured product label by Walgreens (revised Jan 15, 2026). Long sections are shortened; the complete label is on DailyMed.

Active ingredients

Itch Relief Gel NDC products (2)

NDCStrength & formLabelerType
82645-901Diphenhydramine Hydrochloride 2 mg/100mL
Gel
Pharma Nobis, LLCOTC MONOGRAPH DRUG
0363-0353Diphenhydramine Hydrochloride 2 mg/100mL
Gel
WalgreensOTC MONOGRAPH DRUG

Frequently asked questions

What is Itch Relief Gel used for?

Directions Do not use more than directed. Adults and children 2 years of age and older: apply to affected area not more than 3 to 4 times daily.

Who makes Itch Relief Gel?

Itch Relief Gel is listed by 2 labelers in the FDA NDC directory, including Pharma Nobis, LLC, Walgreens.