Leader Lice Killing
Piperonyl Butoxide, Pyrethrum Extract · Shampoo · Topical
Active ingredient
Active Ingredient Piperonyl butoxide 4% Pyrethrum extract (equivalent to 0.33% pyrethrins)
Purpose
Purposes Lice Treatment
Uses
Uses treats head, pubic (crab), and body lice
Warnings
Warnings For external use only Do not use near eyes inside nose, mouth, or vagina on lice in eyebrows or eyelashes. See a doctor if lice are present in these areas. Ask doctor before use if you are allergic to ragweed. May cause breathing difficulty or an asthmatic attack When using this product keep eyes tightly closed and protect eyes with a washcloth or towel if product gets into eyes, flush with water right away scalp itching or redness may occur Stop and ask a doctor if breathing difficulty occurs eye irritation occurs skin or scalp irritation continues or infection occurs Keep out of reach of children If swallowed, get medical help or contact a Poison Control Center right away.
Do not use
Do not use near eyes inside nose, mouth, or vagina on lice in eyebrows or eyelashes. See a doctor if lice are present in these areas.
Ask a doctor before use
Ask doctor before use if you are allergic to ragweed. May cause breathing difficulty or an asthmatic attack
When using this product
When using this product keep eyes tightly closed and protect eyes with a washcloth or towel if product gets into eyes, flush with water right away scalp itching or redness may occur
Stop use and ask a doctor
Stop and ask a doctor if breathing difficulty occurs eye irritation occurs skin or scalp irritation continues or infection occurs
Keep out of reach of children
Keep out of reach of children If swallowed, get medical help or contact a Poison Control Center right away.
Directions
Directions Important: Read warnings before use Adults and children 2 years and over Inspect check each household member with a magnifying glass in bright light for lice/nits (eggs) look for tiny nits near scalp, beginning at back of neck and behind ears examine small sections of hair at a time unlike dandruff which moves when touched, nits stick to the hair if either lice or nits are found, treat with this product Treat apply thoroughly to DRY HAIR or other affected area. For head lice, first apply behind ears and to back of neck. allow product to remain for 10 minutes, but no longer use warm water to form a lather, shampoo, then thoroughly rinse for head lice, towel dry hair and comb out tangles Remove lice and their eggs (nits) se a fine-tooth or special lice/nit comb. Remove any remaining nits by hand (using a throw-away glove). hair should remain slightly damp while removing nits if hair dries during combing, dampen slightly with water for head lice, part hair into sections. Do one section at a time starting on top of the head. Longer hair may take 1 to 2 hours. lift a 1-to 2-inch wide strand of hair. Place comb as close to scalp as possible and comb with a firm, even motion away from scalp. pin back each strand of hair after combing clean comb often. Wipe nits away with tissue and discard in a plastic bag. Seal bag and discard to prevent lice from coming back. after combing, thoroughly recheck for lice/nits. Repeat combing if necessary. check daily for any lice/nits that you missed a second treatment must be done in 7 to 10 days to kill any newly hatched lice if infestation continues, see a doctor for other treatments Children under 2 years: ask a doctor Inspect check each household member with a magnifying glass in bright light for lice/nits (eggs) look for tiny nits near scalp, beginning at back of neck and behind ears examine small sections of hair at a time unlike dandruff which moves when touched, nits stick to the hair if either lice or nits are found, treat with this product Treat apply thoroughly to DRY HAIR or other affected area. For head lice, first apply behind ears and to back of neck. allow product to remain for 10 minutes, but no longer use warm water to form a lather, shampoo, then thoroughly rinse for head lice, towel dry hair and comb out tangles Remove lice and their eggs (nits) se a fine-tooth or special lice/nit comb. Remove any remaining nits by hand (using a throw-away glove). hair should remain slightly damp while removing nits if hair dries during combing, dampen slightly with water for head lice, part hair into sections. Do one section at a time starting on top of the head. Longer hair may take 1 to 2 hours. lift a 1-to 2-inch wide strand of hair. Place comb as close to scalp as possible and comb with a firm, even motion away from scalp. pin back each strand of hair after combing clean comb often. Wipe nits away with tissue and discard in a plastic bag. Seal bag and discard to prevent lice from coming back. after combing, thoroughly recheck for lice/nits. Repeat combing if necessary. check daily for any lice/nits that you missed a second treatment must be done in 7 to 10 days to kill any newly hatched lice if infestation continues, see a doctor for other treatments Children under 2 years: ask a doctor
Inactive ingredients
Inactive Ingredients ammonium laureth sulfate, fragrance, PEG-25 hydrogenated castor oil, polyquaternium-10, purified water, SD-40 alcohol
Questions?
Questions or comments? to report serious side effects due to the use of this product call 1-877-974-7167
Label text from the FDA structured product label by LEADER/ Cardinal Health 110, Inc. (revised Oct 29, 2025). Long sections are shortened; the complete label is on DailyMed.
Active ingredients
- Pyrethrum Extract in 1 product
- Piperonyl Butoxide in 1 product
Leader Lice Killing NDC products (1)
| NDC | Strength & form | Labeler | Type |
|---|---|---|---|
| 70000-0633 | Pyrethrum Extract .33 g/100mL; Piperonyl Butoxide 4 g/100mL Shampoo | LEADER/ Cardinal Health 110, Inc. | OTC MONOGRAPH DRUG |
Frequently asked questions
What is Leader Lice Killing used for?
Uses treats head, pubic (crab), and body lice
Who makes Leader Lice Killing?
Leader Lice Killing is listed by 1 labeler in the FDA NDC directory, including LEADER/ Cardinal Health 110, Inc..