Leader Mucus Relief D

guaifenesin, pseudoephedrine hydrochloride · Tablet, Multilayer, Extended Release · Oral

Over the counter Expectorant alpha-Adrenergic Agonist

Active ingredient

Active ingredients (in each extended-release tablet) Guaifenesin 1200 mg Pseudoephedrine HCl 120 mg

Purpose

Purposes Expectorant Nasal Decongestant

Uses

Uses
• helps loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus and make coughs more productive
• temporarily relieves nasal congestion due to:
• common cold
• hay fever
• upper respiratory allergies
• temporarily restores freer breathing through the nose
• promotes nasal and/or sinus drainage
• temporarily relieves sinus congestion and pressure

Warnings

Warnings Do not use if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. Ask a doctor before use if you have
• heart disease
• high blood pressure
• thyroid disease
• diabetes
• trouble urinating due to an enlarged prostate gland
• persistent or chronic cough such as occurs with smoking, asthma, chronic bronchitis, or emphysema
• cough accompanied by too much phlegm (mucus) When using this product
• do not use more than directed Stop use and ask a doctor if
• you get nervous, dizzy, or sleepless
• symptoms do not get better within 7 days, come back or occur with a fever, rash, or persistent headache. These could be signs of a serious illness. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222).

Do not use

Do not use if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.

Ask a doctor before use

Ask a doctor before use if you have
• heart disease
• high blood pressure
• thyroid disease
• diabetes
• trouble urinating due to an enlarged prostate gland
• persistent or chronic cough such as occurs with smoking, asthma, chronic bronchitis, or emphysema
• cough accompanied by too much phlegm (mucus)

When using this product

When using this product
• do not use more than directed

Stop use and ask a doctor

Stop use and ask a doctor if
• you get nervous, dizzy, or sleepless
• symptoms do not get better within 7 days, come back or occur with a fever, rash, or persistent headache. These could be signs of a serious illness.

Pregnancy or breast-feeding

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children

Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222).

Directions

Directions
• do not crush, chew, or break extended-release tablet
• take with a full glass of water
• this product can be administered without regard for timing of meals
• adults and children 12 years and older: 1 extended-release tablet every 12 hours; not more than 2 extended-release tablets in 24 hours
• children under 12 years of age: do not use

Inactive ingredients

Inactive ingredients carbomer homopolymer type B, colloidal silicon dioxide, FD&C yellow #6 aluminum lake, hypromellose, magnesium stearate, microcrystalline cellulose, sodium starch glycolate

Questions?

Questions or comments? 1-800-719-9260

Label text from the FDA structured product label by Cardinal Health 110, LLC. dba Leader (revised May 26, 2026). Long sections are shortened; the complete label is on DailyMed.

Active ingredients

Leader Mucus Relief D NDC products (2)

NDCStrength & formLabelerType
70000-0719Guaifenesin 1200 mg/1; Pseudoephedrine Hydrochloride 120 mg/1
Tablet, Multilayer, Extended Release
Cardinal Health 110, LLC. dba LeaderANDA
70000-0720Guaifenesin 600 mg/1; Pseudoephedrine Hydrochloride 60 mg/1
Tablet, Multilayer, Extended Release
Cardinal Health 110, LLC. dba LeaderANDA

Frequently asked questions

What is Leader Mucus Relief D used for?

Uses • helps loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus and make coughs more productive • temporarily relieves nasal congestion due to: • common cold • hay fever • upper respiratory allergies • temporarily restores freer breathing through the nose • promotes nasal and/or sinus drainage • temporarily relieves sinus congestion and…

Who makes Leader Mucus Relief D?

Leader Mucus Relief D is listed by 1 labeler in the FDA NDC directory, including Cardinal Health 110, LLC. dba Leader.