Magnesium Chloride

Injection · Intravenous

Prescription (Rx) Calculi Dissolution Agent Osmotic Laxative

Uses

As an electrolyte replenisher in magnesium deficiencies.

Dosage and administration

For intravenous infusion: 4 grams in 250 mL of 5% Dextrose Injection, at a rate not exceeding 3 mL per minute. Serum magnesium levels should serve as a guide to continued dosage.

Contraindications

Magnesium Chloride Injection should not be administered if there is renal impairment, marked myocardial disease or to comatose patients.

Warnings

Do not use if a precipitate is present.

Precautions

The usual precautions for parenteral administration should be observed. Administer with caution if flushing and sweating occurs. A preparation of a calcium salt should be readily available for intravenous injection to counteract potential serious signs of magnesium intoxication. As long as deep tendon reflexes are active it is probable that the patient will not develop respiratory paralysis. Respiration and blood pressure should be carefully observed during and after administration of Magnesium Chloride Injection. Pregnancy Animal reproduction studies have not been conducted with magnesium chloride. It is also not known whether magnesium chloride can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Magnesium Chloride should be given to a pregnant woman only if clearly needed.

Side effects

Flushing, sweating, sharply lowered blood pressure, hypothermia, stupor and ultimately respiratory depression.

Pregnancy

Pregnancy Animal reproduction studies have not been conducted with magnesium chloride. It is also not known whether magnesium chloride can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Magnesium Chloride should be given to a pregnant woman only if clearly needed.

Description

Magnesium Chloride Injection is a sterile solution of Magnesium Chloride Hexahydrate in Water for Injection q.s. Each mL contains Magnesium Chloride Hexahydrate 200 mg, Sodium Chloride 9 mg, Benzyl Alcohol 1% as a preservative, Water for Injection, q.s. pH adjusted with Hydrochloric Acid and/or Sodium Hydroxide. Total osmolarity equivalent to 2.951 mOsm/mL. Contains 1.97 mEq of Mg ++ and Cl - per mL. The structural formula is MgCl 2
• 6H 2 O

How supplied

Magnesium Chloride Injection 200 mg/mL (20% w/v). NDC 67457-134-50 50 mL Multiple-Dose Vial. Individually boxed. Store at 20° to 25°C (68° to 77°F). [See USP Controlled Room Temperature.] Manufactured for: Mylan Institutional LLC Morgantown, WV 26505 Manufactured by: Mylan Institutional Galway, Ireland 1084L101 Revised: 10/2021 MI:MAGNIJ:R4

Label text from the FDA structured product label by Mylan Institutional LLC (revised Oct 15, 2021). Long sections are shortened; the complete label is on DailyMed.

Active ingredients

Magnesium Chloride NDC products (1)

NDCStrength & formLabelerType
67457-134Magnesium Chloride 200 mg/mL
Injection
Mylan Institutional LLCUNAPPROVED DRUG OTHER

Frequently asked questions

What is Magnesium Chloride used for?

As an electrolyte replenisher in magnesium deficiencies.

What are the side effects of Magnesium Chloride?

Flushing, sweating, sharply lowered blood pressure, hypothermia, stupor and ultimately respiratory depression. See the full label for the complete list.

Who makes Magnesium Chloride?

Magnesium Chloride is listed by 1 labeler in the FDA NDC directory, including Mylan Institutional LLC.