Maximum Strength Mucinex Sinus-Max Pressure, Pain and Cough

Acetaminophen, Dextromethorphan Hydrobromide, Guaifenesin, and Phenylephrine Hydrochloride · Tablet, Film Coated · Oral

Over the counter Expectorant Sigma-1 Agonist Uncompetitive N-methyl-D-aspartate Receptor Antagonist

Active ingredient

Active ingredients (in each caplet) Acetaminophen 325 mg Guaifenesin 200 mg

Purpose

Acetaminophen 325 mg ........ Pain reliever/ fever reducer Guaifenesin 200 mg.................... Expectorant

Uses

Uses ■ temporarily relieves these common cold and flu symptoms: ■ minor aches and pains ■ headache ■ sore throat ■ helps loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus and make coughs more productive ■ temporarily reduces fever

Warnings

Warnings Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take: ■ more than 12 caplets in 24 hours, which is the maximum daily amount for this product ■ with other drugs containing acetaminophen ■ 3 or more alcoholic drinks daily while using this product Allergy alert: Acetaminophen may cause severe skin reactions. Symptoms may include: ■ skin reddening ■ blisters ■ rash If a skin reaction occurs, stop use and seek medical help right away. Sore throat warning : If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly. Do not use ■ with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. Ask a doctor before use if you have ■ liver disease ■ persistent or chronic cough such as occurs with smoking, asthma, chronic bronchitis, or emphysema ■ cough that occurs with too much phlegm (mucus) Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin When using this product do not use more than directed Stop use and ask a doctor if ■ pain or cough gets worse or lasts more than 7 days ■ fever gets worse or lasts more than 3 days ■ redness or swelling is present ■ new symptoms occur ■ cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition. If pregnant or breast-feeding, ask a health professional before use. Overdose warning: Taking more than the recommended dose (overdose) may cause liver damage. In case of overdose, get medical help or contact a Poison Control Center right away. Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.

Keep out of reach of children

Keep out of reach of children.

Directions

Directions ■ do not take more than directed (see Overdose warning) ■ do not take more than 12 caplets in any 24-hour period ■ adults and children 12 years of age and over: take 2 caplets every 4 hours ■ children under 12 years of age: do not use

Inactive ingredients

Inactive ingredients croscarmellose sodium, FD&C red no. 40 aluminum lake, FD&C yellow no. 6 aluminum lake, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polyvinyl alcohol, povidone, talc, titanium dioxide

Questions?

Questions? 1-866-MUCINEX (1-866-682-4639)

Label text from the FDA structured product label by Reckitt Benckiser LLC (revised May 13, 2026). Long sections are shortened; the complete label is on DailyMed.

Active ingredients

Maximum Strength Mucinex Sinus-Max Pressure, Pain and Cough NDC products (2)

NDCStrength & formLabelerType
63824-242Acetaminophen 325 mg/1; Dextromethorphan Hydrobromide 10 mg/1; Guaifenesin 200 mg/1; Phenylephrine Hydrochloride 5 mg/1
Tablet, Film Coated
Reckitt Benckiser LLCOTC MONOGRAPH DRUG
72854-208Guaifenesin 200 mg/1; Acetaminophen 325 mg/1
Tablet, Film Coated
Reckitt Benckiser LLCOTC MONOGRAPH DRUG

Frequently asked questions

What is Maximum Strength Mucinex Sinus-Max Pressure, Pain and Cough used for?

Uses ■ temporarily relieves these common cold and flu symptoms: ■ minor aches and pains ■ headache ■ sore throat ■ helps loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus and make coughs more productive ■ temporarily reduces fever

Who makes Maximum Strength Mucinex Sinus-Max Pressure, Pain and Cough?

Maximum Strength Mucinex Sinus-Max Pressure, Pain and Cough is listed by 1 labeler in the FDA NDC directory, including Reckitt Benckiser LLC.