McKesson Acetaminophen 325

Acetaminophen · Tablet, Coated · Oral

Over the counter

Active ingredient

Active ingredient (in each tablet) Acetaminophen 325 mg

Purpose

Purpose Pain reliever/fever reducer

Uses

Uses temporarily relieves of minor aches and pains due to: ■ headache ■ muscular aches ■ minor arthritis pain ■ backache ■ the common cold ■ toothache ■ premenstrual and menstrual cramps ■ temporarily reduces fever

Warnings

Warnings Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take: ■ more than 4,000 mg in 24 hours, which is the maximum daily amount ■ with other drugs containing acetaminophen ■ 3 or more alcoholic drinks every day while using this product Allergy alert: Acetaminophen may cause severe skin reactions. Symptoms may include: ■ skin reddening ■ blisters ■ rash If a skin reaction occurs, stop use and seek medical help right away.

Do not use

Do not use ■ with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. ■ if you are allergic to acetaminophen or any of the inactive ingredients in this product

Ask a doctor before use

Ask a doctor before use if you have ■ liver disease

Ask a doctor or pharmacist

Ask a doctor or pharmacist before use if ■ you are taking the blood thinning drug warfarin

Stop use and ask a doctor

Stop using and ask a doctor if ■ pain gets worse and lasts for more than 10 days ■ fever gets worse or lasts for more than 3 days ■ new symptoms occur ■ redness or swelling is present These could be signs of a serious condition

Keep out of reach of children

If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. Overdose Warning: In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222). Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.

Directions

Directions ■ do not use more than directed (see overdose warning) Adults and children: (12 years and over) ■ take 2 tablets every 4 to 6 hours while symptoms last. ■ do not take more than 10 tablets in 24 hours, unless directed by a doctor ■ do not use for more than 10 days unless directed by a doctor Children under 12 years: ■ Ask a doctor

Inactive ingredients

Inactive ingredients corn starch, hypromellose, polyethylene glycol, povidne, pregelantinized starch, sodium starch glycolate, stearic acid, titanium dioxide

Questions?

Questions or comments? Call 1-800-777-4908

Label text from the FDA structured product label by McKesson Medical-Surgical, Inc. (revised Sep 9, 2025). Long sections are shortened; the complete label is on DailyMed.

Active ingredients

McKesson Acetaminophen 325 NDC products (1)

NDCStrength & formLabelerType
68599-4679Acetaminophen 325 mg/1
Tablet, Coated
McKesson Medical-Surgical, Inc.OTC MONOGRAPH DRUG

Frequently asked questions

What is McKesson Acetaminophen 325 used for?

Uses temporarily relieves of minor aches and pains due to: ■ headache ■ muscular aches ■ minor arthritis pain ■ backache ■ the common cold ■ toothache ■ premenstrual and menstrual cramps ■ temporarily reduces fever

Who makes McKesson Acetaminophen 325?

McKesson Acetaminophen 325 is listed by 1 labeler in the FDA NDC directory, including McKesson Medical-Surgical, Inc..