Mucinex D

Guaifenesin and Pseudoephedrine Hydrochloride · Tablet, Extended Release · Oral

Over the counter Expectorant alpha-Adrenergic Agonist

Active ingredient

Active ingredients (in each extended-release tablet) Purposes Guaifenesin 600 mg Expectorant Pseudoephedrine HCl 60 mg Nasal Decongestant

Purpose

Active ingredients (in each extended-release tablet) Purposes Guaifenesin 600 mg Expectorant Pseudoephedrine HCl 60 mg Nasal Decongestant

Uses

Uses helps loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus and make coughs more productive temporarily relieves nasal congestion due to: common cold hay fever upper respiratory allergies temporarily restores freer breathing through the nose promotes nasal and/or sinus drainage temporarily relieves sinus congestion and pressure

Warnings

Warnings Do not use if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. Ask a doctor before use if you have heart disease high blood pressure thyroid disease diabetes trouble urinating due to an enlarged prostate gland persistent or chronic cough such as occurs with smoking, asthma, chronic bronchitis, or emphysema cough accompanied by too much phlegm (mucus) When using this product do not use more than directed Stop use and ask a doctor if you get nervous, dizzy, or sleepless symptoms do not get better within 7 days, come back or occur with a fever, rash, or persistent headache. These could be signs of a serious illness. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.

Do not use

Do not use if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.

Ask a doctor before use

Ask a doctor before use if you have heart disease high blood pressure thyroid disease diabetes trouble urinating due to an enlarged prostate gland persistent or chronic cough such as occurs with smoking, asthma, chronic bronchitis, or emphysema cough accompanied by too much phlegm (mucus)

When using this product

When using this product do not use more than directed

Stop use and ask a doctor

Stop use and ask a doctor if you get nervous, dizzy, or sleepless symptoms do not get better within 7 days, come back or occur with a fever, rash, or persistent headache. These could be signs of a serious illness.

Pregnancy or breast-feeding

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children

Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.

Directions

Directions do not crush, chew, or break extended-release tablet take with a full glass of water this product can be administered without regard for timing of meals adults and children 12 years and older: 2 extended-release tablets every 12 hours; not more than 4 extended-release tablets in 24 hours children under 12 years of age: do not use

Other information

Other information tamper evident: do not use if carton is open or if printed seal on blister is broken or missing store at 20-25°C (68-77°F)

Inactive ingredients

Inactive ingredients carbomer homopolymer type B; FD&C yellow no. 6 aluminum lake; hypromellose, USP; magnesium stearate, NF; microcrystalline cellulose, NF; sodium starch glycolate, NF

Questions?

Questions? 1-866-MUCINEX (1-866-682-4639)

Label text from the FDA structured product label by Reckitt Benckiser LLC (revised May 27, 2026). Long sections are shortened; the complete label is on DailyMed.

Active ingredients

Mucinex D NDC products (4)

NDCStrength & formLabelerType
50090-1075Guaifenesin 600 mg/1; Pseudoephedrine Hydrochloride 60 mg/1
Tablet, Extended Release
A-S Medication SolutionsNDA
50090-1076Guaifenesin 600 mg/1; Pseudoephedrine Hydrochloride 60 mg/1
Tablet, Extended Release
A-S Medication SolutionsNDA
63824-041Guaifenesin 1200 mg/1; Pseudoephedrine Hydrochloride 120 mg/1
Tablet, Extended Release
Reckitt Benckiser LLCNDA
63824-057Guaifenesin 600 mg/1; Pseudoephedrine Hydrochloride 60 mg/1
Tablet, Extended Release
Reckitt Benckiser LLCNDA

Frequently asked questions

What is Mucinex D used for?

Uses helps loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus and make coughs more productive temporarily relieves nasal congestion due to: common cold hay fever upper respiratory allergies temporarily restores freer breathing through the nose promotes nasal and/or sinus drainage temporarily relieves sinus congestion and pressure

Who makes Mucinex D?

Mucinex D is listed by 2 labelers in the FDA NDC directory, including A-S Medication Solutions, Reckitt Benckiser LLC.