Mucinex Fast-Max Day Cold and Flu and Mucinex Nightshift Night Severe Cold and Flu
acetaminophen, dextromethorphan hydrobromide, guaifenesin, phenylephrine hydrochloride, and triprolidine hydrochloride · Kit
Active ingredient
Daytime Cold & Flu Acetaminophen 325 mg Dextromethorphan HBr 10 mg Mucinex Nighttime Cold & Flu Acetaminophen 325 mg Dextromethorphan HBr 10 mg Triprolidine HCl 1.25 mg Active ingredients (in each caplet) Mucinex Fast-Max Day Cold & Flu Purposes Acetaminophen 325 mg Pain reliever/fever reducer Dextromethorphan HBr 10 mg Cough suppressant Active ingredients (in each caplet) Mucinex Nightshift Night Severe Cold & Flu Purposes Acetaminophen 325 mg Pain reliever/fever reducer Dextromethorphan HBr 10 mg Cough suppressant Triprolidine HCl 1.25 mg Antihistamine
Purpose
Active ingredients (in each caplet) Mucinex Fast-Max Day Cold & Flu Purposes Acetaminophen 325 mg Pain reliever/fever reducer Dextromethorphan HBr 10 mg Cough suppressant Active ingredients (in each caplet) Mucinex Nightshift Night Severe Cold & Flu Purposes Acetaminophen 325 mg Pain reliever/fever reducer Dextromethorphan HBr 10 mg Cough suppressant Triprolidine HCl 1.25 mg Antihistamine
Uses
Uses Mucinex Fast-Max Day Cold & Flu temporarily relieves these common cold and flu symptoms: cough nasal congestion minor aches and pains sore throat headache stuffy nose sinus congestion and pressure temporarily reduces fever helps loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus and make coughs more productive Mucinex Nightshift Night Severe Cold & Flu temporarily relieves these common cold and flu symptoms: cough nasal congestion minor aches and pains sore throat headache sneezing sinus congestion and pressure runny nose itching of the nose or throat itchy, watery eyes due to hay fever temporarily reduces fever controls cough to help you get to sleep
Warnings
Warnings Liver warning This product contains acetaminophen. Severe liver damage may occur if you take: more than 4,000 mg in 24 hours, which is the maximum daily amount with other drugs containing acetaminophen 3 or more alcoholic drinks daily while using this product Allergy alert Acetaminophen may cause severe skin reactions. Symptoms may include: skin reddening blisters rash If a skin reaction occurs, stop use and seek medical help right away. Sore throat warning If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly. Do not use with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. Ask a doctor before use if you have liver disease heart disease diabetes high blood pressure thyroid disease glaucoma (Nightshift Night Severe Cold & Flu only) trouble urinating due to an enlarged prostate gland a breathing problem such as emphysema or chronic bronchitis (Nightshift Night Severe Cold & Flu only) persistent or chronic cough such as occurs with smoking, asthma, chronic bronchitis, or emphysema cough that occurs with too much phlegm (mucus) Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin taking sedatives or tranquilizers (Nightshift Night Severe Cold & Flu only) When using this product do not use more than directed excitability may occur, especially in children (Nightshift Night Severe Cold & Flu only) marked drowsiness may occur (Nightshift Night Severe Cold & Flu only) alcohol, sedatives, and tranquilizers may increase drowsiness (Nightshift Night Severe Cold & Flu only) avoid alcoholic drinks (Nightshift Night Severe Cold & Flu only) use caution when driving a motor vehicle or operating machinery (Nightshift Night Severe Cold & Flu only) Stop use and ask a doctor if nervousness, dizziness, or sleeplessness occur pain, nasal congestion, or cough gets worse or lasts more than 7 days fever gets worse or lasts more than 3 days redness or swelling is present new symptoms occur cough comes back, or occurs with fever, rash, or headache that lasts. These could be signs of a serious condition. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. Overdose warning Taking more than the recommended dose (overdose) may cause liver damage. In case of overdose, get medical help or contact a Poison Control Center right away. Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.
Do not use
Do not use with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.
Ask a doctor before use
Ask a doctor before use if you have liver disease heart disease diabetes high blood pressure thyroid disease glaucoma (Nightshift Night Severe Cold & Flu only) trouble urinating due to an enlarged prostate gland a breathing problem such as emphysema or chronic bronchitis (Nightshift Night Severe Cold & Flu only) persistent or chronic cough such as occurs with smoking, asthma, chronic bronchitis, or emphysema cough that occurs with too much phlegm (mucus)
Ask a doctor or pharmacist
Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin taking sedatives or tranquilizers (Nightshift Night Severe Cold & Flu only)
When using this product
When using this product do not use more than directed excitability may occur, especially in children (Nightshift Night Severe Cold & Flu only) marked drowsiness may occur (Nightshift Night Severe Cold & Flu only) alcohol, sedatives, and tranquilizers may increase drowsiness (Nightshift Night Severe Cold & Flu only) avoid alcoholic drinks (Nightshift Night Severe Cold & Flu only) use caution when driving a motor vehicle or operating machinery (Nightshift Night Severe Cold & Flu only)
Stop use and ask a doctor
Stop use and ask a doctor if nervousness, dizziness, or sleeplessness occur pain, nasal congestion, or cough gets worse or lasts more than 7 days fever gets worse or lasts more than 3 days redness or swelling is present new symptoms occur cough comes back, or occurs with fever, rash, or headache that lasts. These could be signs of a serious condition.
Pregnancy or breast-feeding
If pregnant or breast-feeding, ask a health professional before use.
Keep out of reach of children
Keep out of reach of children.
Directions
Directions Mucinex Fast-Max Day Cold & Flu do not take more than directed (see Overdose warning ) do not take more than 12 caplets in any 24-hour period adults and children 12 years of age and over: take 2 caplets every 4 hours children under 12 years of age: do not use Mucinex Nightshift Night Severe Cold & Flu do not take more than directed (see Overdose warning ) do not take more than 8 caplets in any 24-hour period adults and children 12 years of age and over: take 2 caplets every 4 hours children under 12 years of age: do not use
Other information
Other information store at 20-25°C (68-77°F)
Inactive ingredients
Inactive ingredients Mucinex Fast-Max Day Cold & Flu croscarmellose sodium, crospovidone, FD&C red no. 40 aluminum lake, FD&C yellow no. 6 aluminum lake, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polyvinyl alcohol, povidone, talc, titanium dioxide Inactive ingredients Mucinex Nightshift Night Severe Cold & Flu croscarmellose sodium, crospovidone, ferric oxide, hydroxypropyl cellulose, mica, microcrystalline cellulose, polyvinyl alcohol, polyvinyl alcohol polyethylene glycol copolymer, povidone, silicon dioxide, stearic acid, talc, titanium dioxide
Questions?
Questions? 1-866-MUCINEX (1-866-682-4639) You may also report side effects to this phone number.
Label text from the FDA structured product label by Reckitt Benckiser LLC (revised May 19, 2026). Long sections are shortened; the complete label is on DailyMed.
Mucinex Fast-Max Day Cold and Flu and Mucinex Nightshift Night Severe Cold and Flu NDC products (2)
| NDC | Strength & form | Labeler | Type |
|---|---|---|---|
| 72854-169 | Kit | Reckitt Benckiser LLC | OTC MONOGRAPH DRUG |
| 72854-241 | Kit | Reckitt Benckiser LLC | OTC MONOGRAPH DRUG |
Frequently asked questions
What is Mucinex Fast-Max Day Cold and Flu and Mucinex Nightshift Night Severe Cold and Flu used for?
Uses Mucinex Fast-Max Day Cold & Flu temporarily relieves these common cold and flu symptoms: cough nasal congestion minor aches and pains sore throat headache stuffy nose sinus congestion and pressure temporarily reduces fever helps loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus and make coughs more productive Mucinex Nightshift Night…
Who makes Mucinex Fast-Max Day Cold and Flu and Mucinex Nightshift Night Severe Cold and Flu?
Mucinex Fast-Max Day Cold and Flu and Mucinex Nightshift Night Severe Cold and Flu is listed by 1 labeler in the FDA NDC directory, including Reckitt Benckiser LLC.