Mucinex Fast-Max Day Severe Congestion and Cough and Mucinex Nightshift Night Cold and Flu
Acetaminophen, Dextromethorphan Hydrobromide, Guaifenesin, Phenylephrine Hydrochloride, and Triprolidine Hydrochloride · Kit
Active ingredient
Active ingredients (in each caplet) Mucinex Fast-Max Day Severe Congestion & Cough Purposes Dextromethorphan HBr 10 mg Cough suppressant Guaifenesin 200 mg Expectorant Phenylephrine HCl 5 mg Nasal decongestant Active ingredients (in each caplet) Mucinex Nightshift Night Cold & Flu Purposes Acetaminophen 325 mg Pain reliever/fever reducer Dextromethorphan HBr 10 mg Cough suppressant Triprolidine HCl 1.25 mg Antihistamine
Purpose
Active ingredients (in each caplet) Mucinex Fast-Max Day Severe Congestion & Cough Purposes Dextromethorphan HBr 10 mg Cough suppressant Guaifenesin 200 mg Expectorant Phenylephrine HCl 5 mg Nasal decongestant Active ingredients (in each caplet) Mucinex Nightshift Night Cold & Flu Purposes Acetaminophen 325 mg Pain reliever/fever reducer Dextromethorphan HBr 10 mg Cough suppressant Triprolidine HCl 1.25 mg Antihistamine
Uses
Uses Mucinex Fast-Max Day Severe Congestion & Cough helps loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus and make coughs more productive temporarily relieves: cough due to minor throat and bronchial irritation as may occur with the common cold or inhaled irritants the impulse to cough to help you get to sleep the intensity of coughing nasal congestion due to a cold Mucinex Nightshift Night Cold & Flu temporarily relieves these common cold and flu symptoms: cough minor aches and pains sore throat headache runny nose sneezing itching of the nose or throat itchy, watery eyes due to hay fever temporarily reduces fever controls cough to help you get to sleep
Warnings
Warnings Liver warning (Nightshift Night Cold & Flu only) This product contains acetaminophen. Severe liver damage may occur if you take: more than 4,000 mg in 24 hours, which is the maximum daily amount with other drugs containing acetaminophen 3 or more alcoholic drinks daily while using this product Allergy alert (Nightshift Night Cold & Flu only) Acetaminophen may cause severe skin reactions. Symptoms may include: skin reddening blisters rash If a skin reaction occurs, stop use and seek medical help right away. Sore throat warning (Nightshift Night Cold & Flu only) If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly. Do not use with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. (Nightshift Night Cold & Flu only) if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. Ask a doctor before use if you have liver disease (Nightshift Night Cold & Flu only) heart disease (Fast-Max Day Severe Congestion & Cough only) high blood pressure (Fast-Max Day Severe Congestion & Cough only) thyroid disease (Fast-Max Day Severe Congestion & Cough only) diabetes (Fast-Max Day Severe Congestion & Cough only) glaucoma (Nightshift Night Cold & Flu only) trouble urinating due to an enlarged prostate gland a breathing problem such as emphysema or chronic bronchitis (Nightshift Night Cold & Flu only) persistent or chronic cough such as occurs with smoking, asthma, chronic bronchitis, or emphysema cough that occurs with too much phlegm (mucus) Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin (Nightshift Night Cold & Flu only) taking sedatives or tranquilizers (Nightshift Night Cold & Flu only) When using this product do not use more than directed excitability may occur, especially in children (Nightshift Night Cold & Flu only) marked drowsiness may occur (Nightshift Night Cold & Flu only) alcohol, sedatives, and tranquilizers may increase drowsiness (Nightshift Night Cold & Flu only) avoid alcoholic drinks (Nightshift Night Cold & Flu only) use caution when driving a motor vehicle or operating machinery (Nightshift Night Cold & Flu only) Stop use and ask a doctor if pain or cough gets worse or lasts more than 7 days (Nightshift Night Cold & Flu only) fever gets worse or lasts more than 3 days (Nightshift Night Cold & Flu only) redness or swelling is present (Nightshift Night Cold & Flu only) new symptoms occur (Nightshift Night Cold & Flu only) cough comes back, or occurs with fever, rash, or headache that lasts. These could be signs of a serious condition. (Nightshift Night Cold & Flu only) nervousness, dizziness, or sleeplessness occur (Fast-Max Day Severe Congestion & Cough only) symptoms do not get better within 7 days or occur with fever (Fast-Max Day Severe Congestion & Cough only) cough lasts more than 7 days, comes back, or occurs with fever, rash, or headache that lasts. These could be signs of a serious condition. (Fast-Max Day Severe Congestion & Cough only) If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. Overdose warning (Nightshift Night Cold & Flu only) Taking more than the recommended dose (overdose) may cause liver damage. Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.
Do not use
Do not use with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. (Nightshift Night Cold & Flu only) if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.
Ask a doctor before use
Ask a doctor before use if you have liver disease (Nightshift Night Cold & Flu only) heart disease (Fast-Max Day Severe Congestion & Cough only) high blood pressure (Fast-Max Day Severe Congestion & Cough only) thyroid disease (Fast-Max Day Severe Congestion & Cough only) diabetes (Fast-Max Day Severe Congestion & Cough only) glaucoma (Nightshift Night Cold & Flu only) trouble urinating due to an enlarged prostate gland a breathing problem such as emphysema or chronic bronchitis (Nightshift Night Cold & Flu only) persistent or chronic cough such as occurs with smoking, asthma, chronic bronchitis, or emphysema cough that occurs with too much phlegm (mucus)
Ask a doctor or pharmacist
Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin (Nightshift Night Cold & Flu only) taking sedatives or tranquilizers (Nightshift Night Cold & Flu only)
When using this product
When using this product do not use more than directed excitability may occur, especially in children (Nightshift Night Cold & Flu only) marked drowsiness may occur (Nightshift Night Cold & Flu only) alcohol, sedatives, and tranquilizers may increase drowsiness (Nightshift Night Cold & Flu only) avoid alcoholic drinks (Nightshift Night Cold & Flu only) use caution when driving a motor vehicle or operating machinery (Nightshift Night Cold & Flu only)
Stop use and ask a doctor
Stop use and ask a doctor if pain or cough gets worse or lasts more than 7 days (Nightshift Night Cold & Flu only) fever gets worse or lasts more than 3 days (Nightshift Night Cold & Flu only) redness or swelling is present (Nightshift Night Cold & Flu only) new symptoms occur (Nightshift Night Cold & Flu only) cough comes back, or occurs with fever, rash, or headache that lasts. These could be signs of a serious condition. (Nightshift Night Cold & Flu only) nervousness, dizziness, or sleeplessness occur (Fast-Max Day Severe Congestion & Cough only) symptoms do not get better within 7 days or occur with fever (Fast-Max Day Severe Congestion & Cough only) cough lasts more than 7 days, comes back, or occurs with fever, rash, or headache that lasts. These could be signs of a serious condition. (Fast-Max Day Severe Congestion & Cough only)
Pregnancy or breast-feeding
If pregnant or breast-feeding, ask a health professional before use.
Keep out of reach of children
Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.
Directions
Directions Mucinex Fast-Max Day Severe Congestion & Cough do not take more than directed do not take more than 12 caplets in any 24-hour period adults and children 12 years of age and over: take 2 caplets every 4 hours children under 12 years of age: do not use Mucinex Nightshift Night Cold & Flu do not take more than directed (see Overdose warning ) do not take more than 8 caplets in any 24-hour period adults and children 12 years of age and over: take 2 caplets every 4 hours children under 12 years of age: do not use
Other information
Other information store at 20-25°C (68-77°F)
Inactive ingredients
Inactive ingredients Mucinex Fast-Max Day Severe Congestion & Cough croscarmellose sodium, FD&C blue no. 2 aluminum lake, FD&C red no. 40 aluminum lake, methacrylic acid-ethyl acrylate copolymer, mica, microcrystalline cellulose, polyethylene glycol 3350, polysorbate 80, polyvinyl alcohol, povidone K29/32, sodium bicarbonate, talc, titanium dioxide Inactive ingredients Mucinex Nightshift Night Cold & Flu croscarmellose sodium, crospovidone, hypromellose, microcrystalline cellulose, polyethylene glycol, polysorbate 80, povidone, titanium dioxide
Questions?
Questions? 1-866-MUCINEX (1-866-682-4639) You may also report side effects to this phone number.
Label text from the FDA structured product label by Reckitt Benckiser LLC (revised May 12, 2026). Long sections are shortened; the complete label is on DailyMed.
Mucinex Fast-Max Day Severe Congestion and Cough and Mucinex Nightshift Night Cold and Flu NDC products (1)
| NDC | Strength & form | Labeler | Type |
|---|---|---|---|
| 72854-242 | Kit | Reckitt Benckiser LLC | OTC MONOGRAPH DRUG |
Frequently asked questions
What is Mucinex Fast-Max Day Severe Congestion and Cough and Mucinex Nightshift Night Cold and Flu used for?
Uses Mucinex Fast-Max Day Severe Congestion & Cough helps loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus and make coughs more productive temporarily relieves: cough due to minor throat and bronchial irritation as may occur with the common cold or inhaled irritants the impulse to cough to help you get to sleep the intensity of coughing…
Who makes Mucinex Fast-Max Day Severe Congestion and Cough and Mucinex Nightshift Night Cold and Flu?
Mucinex Fast-Max Day Severe Congestion and Cough and Mucinex Nightshift Night Cold and Flu is listed by 1 labeler in the FDA NDC directory, including Reckitt Benckiser LLC.