Multi-Symptom Allergy

Acetaminophen, Chlorpheniramine maleate, Phenylephrine HCl · Tablet, Coated · Oral

Over the counter Histamine-1 Receptor Antagonist alpha-1 Adrenergic Agonist

Active ingredient

Active ingredients (in each gelcap) Acetaminophen 325 mg Chlorpheniramine maleate 2 mg Phenylephrine HCl 5 mg

Purpose

Purpose Pain reliever Antihistamine Nasal decongestant

Uses

Uses temporarily relieves these symptoms of hay fever or other upper respiratory allergies: runny nose and sneezing nasal congestion minor aches and pains headache sinus congestion and pressure temporarily relieves these additional symptoms of hay fever: itchy, watery eyes itching of the nose or throat helps clear nasal passages helps decongest sinus openings and passages

Warnings

Warnings Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take more than 4,000 mg of acetaminophen in 24 hours with other drugs containing acetaminophen 3 or more alcoholic drinks every day while using this product Allergy alert: Acetaminophen may cause severe skin reactions. Symptoms may include: skin reddening blisters rash If a skin reaction occurs, stop use and seek medical help right away. Do not use with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. if you have ever had an allergic reaction to this product or any of its ingredients Ask a doctor before use if you have a breathing problem such as emphysema or chronic bronchitis high blood pressure heart disease diabetes liver disease difficulty in urination due to enlargement of the prostate gland glaucoma thyroid disease Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin taking sedatives or tranquilizers When using this product do not exceed recommended dosage excitability may occur, especially in children alcohol, sedatives, and tranquilizers may increase drowsiness drowsiness may occur use caution when driving a motor vehicle or operating machinery avoid alcoholic beverages Stop use and ask a doctor if nervousness, dizziness, or sleeplessness occur pain or nasal congestion gets worse or lasts more than 7 days new symptoms occur fever gets worse or lasts more than 3 days redness or swelling is present These could be signs of a serious condition. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. Prompt medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.

Do not use

Do not use with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. if you have ever had an allergic reaction to this product or any of its ingredients

Ask a doctor before use

Ask a doctor before use if you have a breathing problem such as emphysema or chronic bronchitis high blood pressure heart disease diabetes liver disease difficulty in urination due to enlargement of the prostate gland glaucoma thyroid disease

Ask a doctor or pharmacist

Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin taking sedatives or tranquilizers

When using this product

When using this product do not exceed recommended dosage excitability may occur, especially in children alcohol, sedatives, and tranquilizers may increase drowsiness drowsiness may occur use caution when driving a motor vehicle or operating machinery avoid alcoholic beverages

Stop use and ask a doctor

Stop use and ask a doctor if nervousness, dizziness, or sleeplessness occur pain or nasal congestion gets worse or lasts more than 7 days new symptoms occur fever gets worse or lasts more than 3 days redness or swelling is present These could be signs of a serious condition.

Pregnancy or breast-feeding

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children

Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. Prompt medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.

Directions

Directions do not take more than directed adults and children 12 years and over take 2 gelcaps every 4 hours do not take more than 10 gelcaps in 24 hours children under 12 years: ask a doctor

Other information

Other information contains FD&C Yellow #5 (tartrazine) as a color additive TAMPER EVIDENT: DO NOT USE IF OUTER PACKAGE IS OPENED OR BLISTER IS TORN OR BROKEN store at 25°C (77°F); excursions permitted between 15°-30°C (59°-86°F) avoid high humidity see end flap for expiration date and lot number

Inactive ingredients

Inactive ingredients corn starch, croscarmellose sodium, crospovidone, FD&C red #3, FD&C red #40, FD&C yellow #5, FD&C yellow #6, gelatin, hydroxypropyl cellulose, hypromellose, iron oxide black, iron oxide red, iron oxide yellow, magnesium stearate, microcrystalline cellulose, polyethylene glycol, povidone, propylene glycol, shellac glaze, silicon dioxide, stearic acid, titanium dioxide

Questions?

Questions or comments? 1-800-426-9391

Label text from the FDA structured product label by Walgreen Company (revised Aug 28, 2026). Long sections are shortened; the complete label is on DailyMed.

Active ingredients

Multi-Symptom Allergy NDC products (1)

NDCStrength & formLabelerType
0363-0559Acetaminophen 325 mg/1; Chlorpheniramine Maleate 2 mg/1; Phenylephrine Hydrochloride 5 mg/1
Tablet, Coated
Walgreen CompanyOTC MONOGRAPH DRUG

Frequently asked questions

What is Multi-Symptom Allergy used for?

Uses temporarily relieves these symptoms of hay fever or other upper respiratory allergies: runny nose and sneezing nasal congestion minor aches and pains headache sinus congestion and pressure temporarily relieves these additional symptoms of hay fever: itchy, watery eyes itching of the nose or throat helps clear nasal passages helps decongest sinus openings and passages

Who makes Multi-Symptom Allergy?

Multi-Symptom Allergy is listed by 1 labeler in the FDA NDC directory, including Walgreen Company.