Multi-Symptom Cold Relief
Acetaminophen, Dextromethorphan HBr, Phenylephrine HCl , Guaifenesin, , · Tablet, Film Coated · Oral
Active ingredient
Active ingredients (in each caplet) Acetaminophen 325 mg Dextromethorphan HBr 10 mg Guaifenesin 100 mg Phenylephrine HCl 5 mg
Purpose
Purpose Pain reliever/fever reducer Cough suppressant Expectorant Nasal decongestant
Uses
Uses Temporarily relieves these symptoms due to the common cold headache nasal congestion cough minor aches and pains sore throat sinus congestion and pressure helps loosen phlegm (mucus) and thin bronchial secretions to drain bronchial tubes and make cough more productive Temporarily reduces fever.
Warnings
Warnings Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take: more than 4,000 mg of acetaminophen in 24 hours with other drugs containing acetaminophen 3 or more alcoholic drinks every day while using this product Allergy alert: Acetaminophen may cause severe skin reactions. Symptoms may include: skin reddening blisters rash If a skin reaction occurs, stop use and seek medical help right away. Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly.
Do not use
Do not use with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. if you have ever had an allergic reaction to this product or any of its ingredients if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.
Ask a doctor before use
Ask a doctor before use if you have liver disease heart disease high blood pressure thyroid disease diabetes difficulty in urination due to enlargement of the prostate gland cough that occurs with too much phlegm (mucus) persistent or chronic cough that lasts as occurs with smoking, asthma, chronic bronchitis, or emphysema
Ask a doctor or pharmacist
Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin.
When using this product
When using this product do not exceed recommended dosage.
Stop use and ask a doctor
Stop use and ask a doctor if nervousness, dizziness, or sleeplessness occur pain, cough, or nasal congestion gets worse or lasts more than 7 days fever gets worse or lasts more than 3 days redness or swelling is present new symptoms occur cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition.
Pregnancy or breast-feeding
If pregnant or breast-feeding, ask a health professional before use.
Keep out of reach of children
Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. Prompt medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.
Directions
Directions do not take more than directed Adults and children: (12 years and over) take 2 caplets every 4 hours not to take more than 10 caplets in 24 hours Children under 12 years: ask a doctor
Inactive ingredients
Inactive ingredients corn starch, crospovidone, FD&C yellow # 6 aluminum lake, magnesium stearate, maltodextrin, microcrystalline cellulose, polyethylene glycol, polyvinyl alcohol, povidone,silicon dioxide, sodium starch glycolate, stearic acid, talc, titanium dioxide
Questions?
Questions or comments? 1-800-869-6970
Label text from the FDA structured product label by Unifirst First Aid Corporation (revised Sep 8, 2025). Long sections are shortened; the complete label is on DailyMed.
Active ingredients
- Dextromethorphan Hydrobromide in 1 product
- Guaifenesin in 1 product
- Acetaminophen in 1 product
- Phenylephrine Hydrochloride in 1 product
Multi-Symptom Cold Relief NDC products (1)
| NDC | Strength & form | Labeler | Type |
|---|---|---|---|
| 47682-047 | Dextromethorphan Hydrobromide 10 mg/1; Guaifenesin 100 mg/1; Acetaminophen 325 mg/1; Phenylephrine Hydrochloride 5 mg/1 Tablet, Film Coated | Unifirst First Aid Corporation | OTC MONOGRAPH DRUG |
Frequently asked questions
What is Multi-Symptom Cold Relief used for?
Uses Temporarily relieves these symptoms due to the common cold headache nasal congestion cough minor aches and pains sore throat sinus congestion and pressure helps loosen phlegm (mucus) and thin bronchial secretions to drain bronchial tubes and make cough more productive Temporarily reduces fever.
Who makes Multi-Symptom Cold Relief?
Multi-Symptom Cold Relief is listed by 1 labeler in the FDA NDC directory, including Unifirst First Aid Corporation.