Nighttime Severe, Cold and Flu, 24-7 Life by 7-Eleven

Acetaminophen, dextromethorphan hbr, doxylamine succinate, phenylephrine hcl tablet, film coated · Tablet, Film Coated · Oral

Over the counter Antihistamine Sigma-1 Agonist Uncompetitive N-methyl-D-aspartate Receptor Antagonist

Active ingredient

​Active ingredients Active ingredients (in each caplet) Acetaminophen 325 Dextromethorphan HBr 10 mg Doxylamine succinate 6.25 mg Doxylamine succinate 6.25 mg Purpose ​Purpose Pain reliever/fever reducer Cough suppressant Antihistamine Nasal decongestant

Purpose

Purpose ​Purpose Pain reliever/fever reducer Cough suppressant Antihistamine Nasal decongestant

Uses

Uses Uses temporarily relieves common cold and flu symptoms: minor aches and pains sinus congestion and pressure sore throat fever headache nasal congestion cough due to minor throat and bronchial irritation runny nose and sneezing reduces swelling of nasal passages promotes nasal and/or sinus drainage temporarily restores freer breathing through the nose

Warnings

Warnings Warnings Liver warning Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take more than 4,000 mg of acetaminophen in 24 hours with other drugs containing acetaminophen 3 or more alcoholic drinks every day while using this product Allergy Alert Allergy Alert: Acetaminophen may cause severe skin reactions. Symptoms may include: blisters rash skin reddening If a skin reaction occurs, stop use and seek medical help right away. Sore throat warning Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly. Do not use Do not use with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. if you have ever had an allergic reaction to this product or any of its ingredients Ask a doctor before use Ask a doctor before use if you have liver disease diabetes thyroid disease heart disease glaucoma high blood pressure difficulty in urination due to enlargement of the prostate gland a breathing problem or chronic cough that lasts or as occurs with smoking, asthma, chronic bronchitis, or emphysema cough that occurs with too much phlegm (mucus) Ask a doctor or pharmacist before use if Ask a doctor or pharmacist before use if you are taking sedatives or tranquilizers taking the blood thinning drug warfarin When using this product When using this product do not exceed recommended dosage excitability may occur, especially in children marked drowsiness may occur avoid alcoholic beverages
• be careful when driving a motor vehicle or operating machinery alcohol, sedatives, and tranquilizers may increase drowsiness Stop use and ask a doctor if Stop use and ask a doctor if nervousness, dizziness, or sleeplessness occur pain, nasal congestion, or cough gets worse or lasts more than 7 days fever gets worse or lasts more than 3 days redness or swelling is present new symptoms occur cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition. If pregnant or breast-feeding If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. Prompt medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.

Do not use

Do not use Do not use with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. if you have ever had an allergic reaction to this product or any of its ingredients

Ask a doctor before use

Ask a doctor before use Ask a doctor before use if you have liver disease diabetes thyroid disease heart disease glaucoma high blood pressure difficulty in urination due to enlargement of the prostate gland a breathing problem or chronic cough that lasts or as occurs with smoking, asthma, chronic bronchitis, or emphysema cough that occurs with too much phlegm (mucus)

Ask a doctor or pharmacist

Ask a doctor or pharmacist before use if Ask a doctor or pharmacist before use if you are taking sedatives or tranquilizers taking the blood thinning drug warfarin

When using this product

When using this product When using this product do not exceed recommended dosage excitability may occur, especially in children marked drowsiness may occur avoid alcoholic beverages
• be careful when driving a motor vehicle or operating machinery alcohol, sedatives, and tranquilizers may increase drowsiness

Stop use and ask a doctor

Stop use and ask a doctor if Stop use and ask a doctor if nervousness, dizziness, or sleeplessness occur pain, nasal congestion, or cough gets worse or lasts more than 7 days fever gets worse or lasts more than 3 days redness or swelling is present new symptoms occur cough comes back or occurs with rash or headache that lasts. These could be signs of a serious condition.

Pregnancy or breast-feeding

If pregnant or breast-feeding If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children

Keep out of reach of children Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. Prompt medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.

Directions

Directions Directions do not take more than directed do not take more than 8 caplets in 24 hours adults and children 12 years and over: take 2 caplets with water every 4 hours children under 12 years: ask a doctor

Inactive ingredients

Inactive ingredients Inactive ingredients black iron oxide, corn starch, crospovidone, D&C yellow #10 aluminum lake, FD&C blue #1 aluminum lake, FD&C yellow #6 aluminum lake, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate 80, polyvinyl alcohol, povidone, silicon dioxide, sodium starch glycolate, stearic acid, talc, titanium dioxide

Label text from the FDA structured product label by Lil' Drug Store Products, Inc. (revised Dec 2, 2025). Long sections are shortened; the complete label is on DailyMed.

Active ingredients

Nighttime Severe, Cold and Flu, 24-7 Life by 7-Eleven NDC products (1)

NDCStrength & formLabelerType
66715-6505Dextromethorphan Hydrobromide 10 mg/1; Acetaminophen 325 mg/1; Phenylephrine Hydrochloride 5 mg/1; Doxylamine Succinate…
Tablet, Film Coated
Lil' Drug Store Products, Inc.OTC MONOGRAPH DRUG

Frequently asked questions

What is Nighttime Severe, Cold and Flu, 24-7 Life by 7-Eleven used for?

Uses Uses temporarily relieves common cold and flu symptoms: minor aches and pains sinus congestion and pressure sore throat fever headache nasal congestion cough due to minor throat and bronchial irritation runny nose and sneezing reduces swelling of nasal passages promotes nasal and/or sinus drainage temporarily restores freer breathing through the nose

Who makes Nighttime Severe, Cold and Flu, 24-7 Life by 7-Eleven?

Nighttime Severe, Cold and Flu, 24-7 Life by 7-Eleven is listed by 1 labeler in the FDA NDC directory, including Lil' Drug Store Products, Inc..