Pain Reliever PM, Extra Strength, 24-7 Life by 7-Eleven

Acetaminophen, diphenhydramine hcl tablet, film coated · Tablet, Film Coated · Oral

Over the counter Histamine-1 Receptor Antagonist

Active ingredient

Active ingredients Active ingredients (in each caplet) Acetaminophen 500 mg Diphenhydramine HCl 25 mg Purpose Purpose Pain reliever Nighttime sleep-aid

Purpose

Purpose Purpose Pain reliever Nighttime sleep-aid

Uses

Uses Uses temporary relief of occasional headaches and minor aches and pains with accompanying sleeplessness

Warnings

Warnings Warnings Liver warning Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take: more than 4,000 mg of acetaminophen in 24 hours with other drugs containing acetaminophen 3 or more alcoholic drinks every day while using this product Allergy alert Allergy alert: Acetaminophen may cause severe skin reactions. Symptoms may include: skin reddening blisters rash If a skin reaction occurs, stop use and seek medical help right away. Do not use Do not use with any other product containing diphenhydramine, even one used on skin in children under 12 years of age with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. if you have ever had an allergic reaction to this product or any of its ingredients Ask a doctor before use if you have Ask a doctor before use if you have liver disease a breathing problem such as emphysema or chronic bronchitis difficulty in urination due to an enlarged prostate gland glaucoma Ask a doctor or pharmacist before use if you are Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin taking sedatives or tranquilizers When using this product When using this product avoid alcoholic beverages do not drive a motor vehicle or operate machinery drowsiness will occur Stop use and ask a doctor if Stop use and ask a doctor if sleeplessness persists continuously for more than 2 weeks. Insomnia may be a symptom of a serious underlying medical illness. new symptoms occur redness or swelling is present pain gets worse or lasts more than 10 days fever gets worse or lasts more than 3 days These could be signs of a serious condition. If pregnant or breast-feeding If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center (1-800-222-1222) right away. Prompt medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.

Do not use

Do not use Do not use with any other product containing diphenhydramine, even one used on skin in children under 12 years of age with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. if you have ever had an allergic reaction to this product or any of its ingredients

Ask a doctor before use

Ask a doctor before use if you have Ask a doctor before use if you have liver disease a breathing problem such as emphysema or chronic bronchitis difficulty in urination due to an enlarged prostate gland glaucoma

Ask a doctor or pharmacist

Ask a doctor or pharmacist before use if you are Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin taking sedatives or tranquilizers

When using this product

When using this product When using this product avoid alcoholic beverages do not drive a motor vehicle or operate machinery drowsiness will occur

Stop use and ask a doctor

Stop use and ask a doctor if Stop use and ask a doctor if sleeplessness persists continuously for more than 2 weeks. Insomnia may be a symptom of a serious underlying medical illness. new symptoms occur redness or swelling is present pain gets worse or lasts more than 10 days fever gets worse or lasts more than 3 days These could be signs of a serious condition.

Pregnancy or breast-feeding

If pregnant or breast-feeding If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children

Keep out of reach of children Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center (1-800-222-1222) right away. Prompt medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.

Directions

Directions Directions do not take more than directed adults and children 12 years and over: take 2 caplets at bedtime. Do not take more than 2 caplets of this product in 24 hours. children under 12 years: do not use

Inactive ingredients

Inactive ingredients Inactive ingredients colloidal silicon dioxide, corn starch, croscarmellose sodium, FD&C blue #1 aluminum lake, microcrystalline cellulose, polyethylene glycol, polyvinyl alcohol, povidone, stearic acid, talc, titanium dioxide

Label text from the FDA structured product label by Lil' Drug Store Products, Inc. (revised Dec 12, 2025). Long sections are shortened; the complete label is on DailyMed.

Active ingredients

Pain Reliever PM, Extra Strength, 24-7 Life by 7-Eleven NDC products (2)

NDCStrength & formLabelerType
66715-5640Diphenhydramine Hydrochloride 25 mg/1; Acetaminophen 500 mg/1
Tablet, Film Coated
Lil' Drug Store Products, Inc.OTC MONOGRAPH DRUG
66715-8158Diphenhydramine Hydrochloride 25 mg/1; Acetaminophen 500 mg/1
Tablet, Film Coated
Lil' Drug Store Products, Inc.OTC MONOGRAPH DRUG

Frequently asked questions

What is Pain Reliever PM, Extra Strength, 24-7 Life by 7-Eleven used for?

Uses Uses temporary relief of occasional headaches and minor aches and pains with accompanying sleeplessness

Who makes Pain Reliever PM, Extra Strength, 24-7 Life by 7-Eleven?

Pain Reliever PM, Extra Strength, 24-7 Life by 7-Eleven is listed by 1 labeler in the FDA NDC directory, including Lil' Drug Store Products, Inc..