PMS Relief

Acetaminophen, Pamabrom, Pyrilamine Maleate · Liquid · Oral, Sublingual

Over the counter Non-Standardized Fungal Allergenic Extract Calculi Dissolution Agent Copper-containing Intrauterine Device

Active ingredient

Active ingredients (in each caplet) Acetaminophen 500 mg Pamabrom 25 mg Pyrilamine maleate 15 mg

Purpose

Purpose Pain reliever Diuretic Antihistamine

Uses

Uses for the temporary relief of these symptoms associated with menstrual periods: headache bloating cramps backache muscular aches irritability water-weight gain

Warnings

Warnings Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take more than 4,000 mg of acetaminophen in 24 hours with other drugs containing acetaminophen 3 or more alcoholic drinks every day while using this product Allergy alert: Acetaminophen may cause severe skin reactions. Symptoms may include: skin reddening blisters rash If a skin reaction occurs, stop use and seek medical help right away. Do not use with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. if you have ever had an allergic reaction to this product or any of its ingredients Ask a doctor before use if you have difficulty in urination due to enlargement of the prostate gland a breathing problem such as emphysema or chronic bronchitis liver disease glaucoma Ask a doctor or pharmacist before use if you are taking sedatives or tranquilizers taking the blood thinning drug warfarin When using this product drowsiness may occur avoid alcoholic beverages excitability may occur, especially in children alcohol, sedatives and tranquilizers may increase drowsiness use caution when driving a motor vehicle or operating machinery Stop use and ask a doctor if pain gets worse or lasts more than 10 days fever gets worse or lasts more than 3 days new symptoms occur redness or swelling is present These could be signs of a serious condition. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. In case of accidental overdose, get medical help or contact a Poison Control Center right away. Prompt medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.

Do not use

Do not use with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. if you have ever had an allergic reaction to this product or any of its ingredients

Ask a doctor before use

Ask a doctor before use if you have difficulty in urination due to enlargement of the prostate gland a breathing problem such as emphysema or chronic bronchitis liver disease glaucoma

Ask a doctor or pharmacist

Ask a doctor or pharmacist before use if you are taking sedatives or tranquilizers taking the blood thinning drug warfarin

When using this product

When using this product drowsiness may occur avoid alcoholic beverages excitability may occur, especially in children alcohol, sedatives and tranquilizers may increase drowsiness use caution when driving a motor vehicle or operating machinery

Stop use and ask a doctor

Stop use and ask a doctor if pain gets worse or lasts more than 10 days fever gets worse or lasts more than 3 days new symptoms occur redness or swelling is present These could be signs of a serious condition.

Pregnancy or breast-feeding

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children

Keep out of reach of children. In case of accidental overdose, get medical help or contact a Poison Control Center right away. Prompt medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.

Directions

Directions do not take more than directed adults and children 12 years and over: take 2 caplets with water every 6 hours as needed do not exceed 6 caplets in a 24 hour period or as directed by a doctor children under 12 years: ask a doctor

Other information

Other information store at 25ºC (77ºF); excursions permitted between 15º-30ºC (59º-86ºF) see end flap for expiration date and lot number

Inactive ingredients

Inactive ingredients corn starch, croscarmellose sodium, crospovidone, FD&C blue #2 aluminum lake, FD&C red #40 aluminum lake, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polyvinyl alcohol, povidone, shellac wax, silicon dioxide, stearic acid, talc, titanium dioxide

Questions?

Questions or comments? 1-800-426-9391

Label text from the FDA structured product label by CVS Pharmacy (revised May 12, 2026). Long sections are shortened; the complete label is on DailyMed.

Active ingredients

PMS Relief NDC products (4)

NDCStrength & formLabelerType
59779-879Acetaminophen 500 mg/1; Pamabrom 25 mg/1; Pyrilamine Maleate 15 mg/1
Tablet, Film Coated
CVS PharmacyOTC MONOGRAPH DRUG
43742-1342Chaste Tree Fruit 6 [hp_X]/mL; Black Cohosh 6 [hp_X]/mL; Potassium Carbonate 6 [hp_X]/mL; Lycopodium Clavatum Spore 6…
Liquid
Deseret Biologicals, Inc.UNAPPROVED HOMEOPATHIC
43742-2199Chaste Tree Fruit 6 [hp_X]/mL; Gold Monosulfide 12 [hp_X]/mL; Candida Albicans 12 [hp_X]/mL; Black Cohosh 6 [hp_X]/mL;…
Liquid
Deseret Biologicals, Inc.UNAPPROVED HOMEOPATHIC
61727-310Copper 10 [hp_X]/4g; Estrone 18 [hp_X]/4g; Histamine Dihydrochloride 8 [hp_X]/4g; Magnesium Phosphate, Tribasic,…
Pellet
Homeocare LaboratoriesUNAPPROVED HOMEOPATHIC

Frequently asked questions

What is PMS Relief used for?

Uses for the temporary relief of these symptoms associated with menstrual periods: headache bloating cramps backache muscular aches irritability water-weight gain

Who makes PMS Relief?

PMS Relief is listed by 3 labelers in the FDA NDC directory, including CVS Pharmacy, Deseret Biologicals, Inc., Homeocare Laboratories.