Polytussin DM
Dextromethorphan HBr, Phenylephrine HCl, Pyrilamine Maleate · Syrup · Oral
Active ingredient
Active ingredients (in each 5 mL teaspoonful) Dextromethorphan HBr............... 7.5 mg Phenylephrine HCl....................... 5 mg Pyrilamine Maleate................. 12.5 mg
Purpose
Antihistamine Cough Suppressant Nasal Decongestant
Uses
Uses temporarily relieves these symptoms due to the common cold, hay fever (allergic rhinitis) or other upper respiratory allergies: runny nose sneezing itching of nose or throat itchy, watery eyes cough due to minor throat and bronchial irritation nasal congestion reduces swelling of nasal passages
Warnings
Warnings Do not exceed recommended dosage. Do not use this product if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.
Ask a doctor before use
Ask a doctor before use if you have a breathing problem such as emphysema or chronic bronchitis glaucoma trouble urinating due to an enlarged prostate gland a cough that lasts or is chronic such as occurs with smoking, asthma or emphysema a cough that occurs with too much phlegm (mucus) heart disease high blood pressure thyroid disease diabetes
Ask a doctor or pharmacist
Ask a doctor or pharmacist before use if you are taking sedatives or tranquilizers.
When using this product
When using this product excitability may occur, especially in children may cause marked drowsiness avoid alcoholic drinks alcohol, sedatives, and tranquilizers may increase the drowsiness effect be careful when driving a motor vehicle or operating machinery
Stop use and ask a doctor
Stop use and ask a doctor if nervousness, dizziness, or sleeplessness occur cough or nasal congestion persists for more than 1 week, tends to recur, or is accompanied by a fever, rash or persistent headache. A persistent cough may be a sign of a serious condition. new symptoms occur
Pregnancy or breast-feeding
If pregnant or breast-feeding, ask a health professional before use.
Keep out of reach of children
Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.
Directions
Directions Do not exceed recommended dosage. Adults and children 12 years of age and over: 2 teaspoonfuls (10 mL) every 4 to 6 hours, not to exceed 12 teaspoonfuls in 24 hours Children 6 to under 12 years of age:1 teaspoonful (5 mL) every 4 to 6 hours, not to exceed 6 teaspoonfuls in 24 hours Children under 6 years of age: Consult a doctor
Inactive ingredients
Inactive ingredients Citric Acid, Flavor, Methylparaben, Potassium Citrate, Propylene Glycol, Propylparaben, Purified water, Sucralose, Sorbitol
Label text from the FDA structured product label by Poly Pharmaceuticals, Inc. (revised Aug 18, 2026). Long sections are shortened; the complete label is on DailyMed.
Active ingredients
- Dextromethorphan Hydrobromide in 1 product
- Pyrilamine Maleate in 1 product
- Phenylephrine Hydrochloride in 1 product
Polytussin DM NDC products (1)
| NDC | Strength & form | Labeler | Type |
|---|---|---|---|
| 50991-132 | Dextromethorphan Hydrobromide 7.5 mg/5mL; Pyrilamine Maleate 12.5 mg/5mL; Phenylephrine Hydrochloride 5 mg/5mL Syrup | Poly Pharmaceuticals, Inc. | OTC MONOGRAPH DRUG |
Frequently asked questions
What is Polytussin DM used for?
Uses temporarily relieves these symptoms due to the common cold, hay fever (allergic rhinitis) or other upper respiratory allergies: runny nose sneezing itching of nose or throat itchy, watery eyes cough due to minor throat and bronchial irritation nasal congestion reduces swelling of nasal passages
Who makes Polytussin DM?
Polytussin DM is listed by 1 labeler in the FDA NDC directory, including Poly Pharmaceuticals, Inc..