Presgen B

dextromethorphan hydrobromide, brompheniramine maleate, phenylephrine hydrochloride · Syrup · Oral

Over the counter Sigma-1 Agonist Uncompetitive N-methyl-D-aspartate Receptor Antagonist alpha-1 Adrenergic Agonist

Active ingredient

Active Ingredients (in each 5 mL teaspoonful) Brompheniramine Maleate 4 mg Dextromethorphan HBr 20 mg Phenylephrine HCl 10 mg

Purpose

Purposes Antihistamine Cough suppressant Nasal decongestant

Uses

Uses
• temporarily relieves:
• runny nose
• sneezing
• itching of the nose or throat
• itchy, watery eyes due to hay fever or other upper respiratory allergies
• temporarily controls cough due to minor throat and bronchial irritation associated with a cold or inhaled irritants
• temporarily relieves nasal congestion due to hay fever or other upper respiratory allergies
• temporarily restores freer breathing through the nose

Warnings

Warnings Do not use if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. Ask a doctor before use if you have
• heart disease
• high blood pressure
• thyroid disease
• diabetes
• glaucoma
• cough that occurs with too much phlegm (mucus)
• trouble urinating due to an enlarged prostate gland
• a breathing problem such as emphysema or chronic bronchitis
• chronic cough that lasts such as occurs with smoking, asthma, or emphysema. Ask a doctor or pharmacist before use if you are taking sedatives or tranquilizers. When using this product
• do not exceed recommended dosage
• excitability may occur, especially in children
• drowsiness may occur; alcohol, sedatives, and tranquilizers may increase the drowsiness effect. Avoid alcoholic beverages while taking this product. Use caution when driving a motor vehicle or operating machinery. Stop use and ask a doctor if
• you get nervous, dizzy, or sleepless
• new symptoms occur
• symptoms do not get better within 7 days or are accompanied by fever
• coughs lasts for more than 7 days, comes back, or is accompanied by fever, rash, or persistent headache. These could be signs of serious conditions. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.

Keep out of reach of children

Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.

Directions

​Directions
• do not take more than 6 doses in any 24-hour period.
• mL = milliliter, tsp = teaspoon adults and children 12 years of age and over 5 mL (1 tsp) every 4 hours children 6 to under 12 years of age 2.5 mL (½ tsp) every 4 hours children under 6 years of age do not use

Other information

Other information
• tamper evident feature: do not use if security seal is torn, broken or missing.
• store at controlled room temperature 15-30°C (59-86°F).
• avoid excessive heat or humidity.

Inactive ingredients

Inactive ingredients citric acid, flavor, glycerin, methylparaben, propylene glycol, propylparaben, purified water, sucralose.

Questions?

Questions or comments? 1-787-767-2072 ​You may also report serious side effects to this phone number. Call weekdays from 8 AM to 4 PM AST

Label text from the FDA structured product label by KRAMER NOVIS (revised Dec 3, 2025). Long sections are shortened; the complete label is on DailyMed.

Active ingredients

Presgen B NDC products (1)

NDCStrength & formLabelerType
52083-637Brompheniramine Maleate 4 mg/5mL; Dextromethorphan Hydrobromide 20 mg/5mL; Phenylephrine Hydrochloride 10 mg/5mL
Syrup
KRAMER NOVISOTC MONOGRAPH DRUG

Frequently asked questions

What is Presgen B used for?

Uses • temporarily relieves: • runny nose • sneezing • itching of the nose or throat • itchy, watery eyes due to hay fever or other upper respiratory allergies • temporarily controls cough due to minor throat and bronchial irritation associated with a cold or inhaled irritants • temporarily relieves nasal congestion due to hay fever or other upper respiratory allergies • temporarily restores…

Who makes Presgen B?

Presgen B is listed by 1 labeler in the FDA NDC directory, including KRAMER NOVIS.