Reliable-1

Oxymetazoline hydrochloride · Spray · Nasal

Over the counter Vasoconstrictor

Active ingredient

Active ingredient Oxymetazoline hydrochloride 0.05%

Purpose

Purpose Nasal decongestant

Uses

Uses ▪ temporarily relieves nasal congestion due to: ▪ common cold ▪ hay fever ▪ upper respiratory allergies ▪ temporarily relieves sinus congestion and pressure ▪ shrinks swollen nasal membranes so you can breathe more freely

Warnings

Warnings

Ask a doctor before use

Ask a doctor before use if you have ▪ heart disease ▪ high blood pressure ▪ thyroid disease ▪ diabetes ▪ trouble urinating due to an enlarged prostate gland

When using this product

When using this product ▪ do not use more than directed ▪ do not use for more than 3 days. Use only as directed. Frequent or prolonged use may cause nasal congestion to recur or worsen. ▪ temporary discomfort such as burning, stinging, sneezing or an increase in nasal discharge may occur ▪ use of this container by more than one person may spread infection

Stop use and ask a doctor

Stop use and ask a doctor if symptoms persist

Pregnancy or breast-feeding

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children

Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away at 1-800-222-1222.

Directions

Directions
• adults and children 6 to under 12 years of age (with adult supervision): 2 or 3 sprays in each nostril not more often than every 10 to 12 hours. Do not exceed 2 doses in any 24-hour period.
• children under 6 years of age: ask a doctor To Use: Shake well before use. Push down cap while turning counter-clockwise and remove cap. Remove clip under rim. Before using the first time, prime metered pump by depressing pump firmly several times. To spray, hold bottle with thumb at base and nozzle between first and second fingers. Without tilting head, insert nozzle into nostril. Fully depress rim with a firm, even stroke and sniff deeply. Wipe nozzle clean after use. Replace clip under rim and secure cap after use.

Other information

Other information
• store at room temperature TAMPER-EVIDENT: DO NOT USE IF PRINTED SEAL OVER CAP IS TORN OR MISSING How to use: Push down cap while turning counter-clockwise and remove cap. Remove clip under rim. Secure cap after use.

Inactive ingredients

Inactive ingredients benzalkonium chloride, benzyl alcohol, edetate disodium, microcrystalline cellulose and carboxymethylcellulose sodium, polyethylene glycol, povidone, purified water, sodium phosphate dibasic, sodium phosphate monobasic, xanthan gum.

Label text from the FDA structured product label by Reliable 1 Laboratories LLC (revised May 21, 2026). Long sections are shortened; the complete label is on DailyMed.

Active ingredients

Reliable-1 NDC products (1)

NDCStrength & formLabelerType
69618-716Oxymetazoline Hydrochloride .05 g/100mL
Spray
Reliable 1 Laboratories LLCOTC MONOGRAPH DRUG

Frequently asked questions

What is Reliable-1 used for?

Uses ▪ temporarily relieves nasal congestion due to: ▪ common cold ▪ hay fever ▪ upper respiratory allergies ▪ temporarily relieves sinus congestion and pressure ▪ shrinks swollen nasal membranes so you can breathe more freely

Who makes Reliable-1?

Reliable-1 is listed by 1 labeler in the FDA NDC directory, including Reliable 1 Laboratories LLC.