Rest Simply
Diphenhydramine Hydrochloride · Tablet, Coated · Oral
Active ingredient
Active ingredient (in each caplet) Diphenhydramine HCl 25 mg
Purpose
Purpose Nighttime sleep-aid
Uses
Use for relief of occasional sleeplessness
Warnings
Warnings Do not use in children under 12 years of age with any other product containing diphenhydramine, even one used on skin Ask a doctor before use if you have a breathing problem such as emphysema or chronic bronchitis trouble urinating due to an enlarged prostate gland glaucoma Ask a doctor or pharmacist before use if you are taking sedatives or tranquilizers When using this product avoid alcoholic drinks drowsiness will occur do not drive a motor vehicle or operate machinery Stop use and ask a doctor if sleeplessness persists continously for more than 2 weeks. Insomnia may be a symptom of serious underlying medical illness. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222).
Do not use
Do not use in children under 12 years of age with any other product containing diphenhydramine, even one used on skin
Ask a doctor before use
Ask a doctor before use if you have a breathing problem such as emphysema or chronic bronchitis trouble urinating due to an enlarged prostate gland glaucoma
Ask a doctor or pharmacist
Ask a doctor or pharmacist before use if you are taking sedatives or tranquilizers
When using this product
When using this product avoid alcoholic drinks drowsiness will occur do not drive a motor vehicle or operate machinery
Stop use and ask a doctor
Stop use and ask a doctor if sleeplessness persists continously for more than 2 weeks. Insomnia may be a symptom of serious underlying medical illness.
Pregnancy or breast-feeding
If pregnant or breast-feeding, ask a health professional before use.
Keep out of reach of children
Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222).
Directions
Directions adults and children 12 years of age and over take 2 caplets at bedtime if needed, or as directed by a doctor children under 12 years of age do not use
Other information
Other information each caplet contains: calcium 45 mg store at room temperature 20-25°C (68-77°F) retain carton for complete product information
Inactive ingredients
Inactive ingredients colloidal silicon dioxide, croscarmellose sodium, dibasic calcium phosphate, FD&C blue #1aluminum lake, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, titanium dioxide
Questions?
Questions or comments? 1-844-705-4384
Label text from the FDA structured product label by HYVEE INC (revised Jan 13, 2026). Long sections are shortened; the complete label is on DailyMed.
Active ingredients
- Diphenhydramine Hydrochloride in 6 products
Rest Simply NDC products (6)
| NDC | Strength & form | Labeler | Type |
|---|---|---|---|
| 63868-772 | Diphenhydramine Hydrochloride 25 mg/1 Tablet, Coated | Chain Drug Marketing Association | OTC MONOGRAPH DRUG |
| 83324-113 | Diphenhydramine Hydrochloride 25 mg/1 Tablet, Coated | CHAIN DRUG MARKETING ASSOCIATION, INC. | OTC MONOGRAPH DRUG |
| 53943-191 | Diphenhydramine Hydrochloride 25 mg/1 Tablet, Coated | DISCOUNT DRUG MART | OTC MONOGRAPH DRUG |
| 72036-091 | Diphenhydramine Hydrochloride 25 mg/1 Tablet, Coated | Harris Teeter | OTC MONOGRAPH DRUG |
| 42507-291 | Diphenhydramine Hydrochloride 25 mg/1 Tablet, Coated | HYVEE INC | OTC MONOGRAPH DRUG |
| 68998-091 | Diphenhydramine Hydrochloride 25 mg/1 Tablet, Coated | Marc Glassman, Inc. | OTC MONOGRAPH DRUG |
Frequently asked questions
What is Rest Simply used for?
Use for relief of occasional sleeplessness
Who makes Rest Simply?
Rest Simply is listed by 6 labelers in the FDA NDC directory, including Chain Drug Marketing Association, CHAIN DRUG MARKETING ASSOCIATION, INC., DISCOUNT DRUG MART, Harris Teeter.