RiVive
Naloxone hydrochloride · Spray · Nasal
Active ingredient
Active ingredient (in each spray) Naloxone hydrochloride 3 mg
Purpose
Purpose Emergency treatment of opioid overdose
Uses
Uses
• to “revive” someone during an overdose from many prescription pain medications or street drugs such as heroin
• this medicine can save a life
Warnings
Warning When using this product some people may experience symptoms when they wake up, such as shaking, sweating, nausea, or feeling angry. This is to be expected.
Directions
Directions Step 1: CHECK if you suspect an overdose
• CHECK for a suspected overdose : the person will not wake up or is very sleepy or not breathing well
• Yell “Wake up!”
• Shake the person gently
• If the person is not awake, go to Step 2 Step 2: GIVE 1 st dose in the nose
• Hold nasal spray device with thumb on plunger and a finger on each side of the nozzle
• Insert nozzle into one nostril and press plunger firmly
• Each nasal spray device contains only one dose of naloxone Step 3: CALL 911
• Get medical help immediately after giving the first dose
• Call 911 now Step 4: WATCH & GIVE
• WAIT 2-3 minutes after the 1 st dose to give the medicine time to work
• If the person wakes up : Go to Step 5
• If the person does not wake up :
• Give a second dose of medicine using a new nasal spray device
• It is safe to keep giving doses every 2-3 minutes until the person wakes up Step 5: STAY
• STAY until ambulance arrives: even if the person wakes up
• GIVE another dose if the person becomes very sleepy again
• You may need to give all the doses in the pack Step 1 Step 2 Step 3 Step 4 Step 5
Inactive ingredients
Inactive ingredients hydrochloric acid, purified water, sodium chloride, sodium hydroxide, trisodium citrate dihydrate
Questions?
Questions? for more information call toll-free (888)-412-7454 or go to www.RiVive.com
Label text from the FDA structured product label by Harm Reduction Therapeutics, Inc. (revised Jan 13, 2026). Long sections are shortened; the complete label is on DailyMed.
Active ingredients
- Naloxone Hydrochloride in 1 product
RiVive NDC products (1)
| NDC | Strength & form | Labeler | Type |
|---|---|---|---|
| 82954-0100 | Naloxone Hydrochloride 3 mg/.1mL Spray | Harm Reduction Therapeutics, Inc. | NDA |
Frequently asked questions
What is RiVive used for?
Uses • to “revive” someone during an overdose from many prescription pain medications or street drugs such as heroin • this medicine can save a life
Who makes RiVive?
RiVive is listed by 1 labeler in the FDA NDC directory, including Harm Reduction Therapeutics, Inc..