Signature numbing cream
5% Lidocaine · Cream · Rectal, Topical
Active ingredient
5% Lidocaine
Purpose
Temporary relief of pain, itching, soreness, or burning in the perianal area from anorectal disorders.
Uses
Adults and children 12 years and older: When practical, cleanse the affected area with mild soap andwarm water and rinse thoroughly. Gently dry by patting or blotting with toilet tissue or a soft clothbefore application of this product.Apply to the affected area up to 6 times daily.Children under 12 years: Consult a doctor.
Warnings
For external use only
When using this product
Wash the area with soap and water
Stop use and ask a doctor
Allergic reaction or rectal bleeding occurs.Redness,irritation, swelling, or pain increases.Condition worsens or lasts >7 days
Keep out of reach of children
KEEP OUT OF CHILDREN SECTION.
Directions
Apply 1-3 times a week
Inactive ingredients
Benzyl Alcohol, Carbomer 934, Lecithin (Soybean), Mentha Arvensis Leaf Extract, Chrysanthemum Indicum Extract, Portulaca Oleracea Extract, Propylene Glycol, Tocopheryl Acetate, Water
Label text from the FDA structured product label by Shengnan (Guangzhou) Cosmetics Co., LTD (revised Jan 10, 2026). Long sections are shortened; the complete label is on DailyMed.
Active ingredients
- Lidocaine in 4 products
Signature numbing cream NDC products (4)
| NDC | Strength & form | Labeler | Type |
|---|---|---|---|
| 84019-033 | Lidocaine 100 mg/g Cream | Shengnan (Guangzhou) Cosmetics Co., LTD | OTC MONOGRAPH DRUG |
| 84019-034 | Lidocaine 100 mg/g Cream | Shengnan (Guangzhou) Cosmetics Co., LTD | OTC MONOGRAPH DRUG |
| 84019-039 | Lidocaine 50 mg/g Cream | Shengnan (Guangzhou) Cosmetics Co., LTD | OTC MONOGRAPH DRUG |
| 84019-041 | Lidocaine 50 mg/g Cream | Shengnan (Guangzhou) Cosmetics Co., LTD | OTC MONOGRAPH DRUG |
Frequently asked questions
What is Signature numbing cream used for?
Adults and children 12 years and older: When practical, cleanse the affected area with mild soap andwarm water and rinse thoroughly. Gently dry by patting or blotting with toilet tissue or a soft clothbefore application of this product.Apply to the affected area up to 6 times daily.Children under 12 years: Consult a doctor.
Who makes Signature numbing cream?
Signature numbing cream is listed by 1 labeler in the FDA NDC directory, including Shengnan (Guangzhou) Cosmetics Co., LTD.