Simply Sleep

diphenhydramine hydrochloride · Tablet, Film Coated · Oral

Over the counter Histamine-1 Receptor Antagonist

Active ingredient

Active ingredient (in each caplet) Diphenhydramine HCl 25 mg

Purpose

Purpose Nighttime sleep aid

Uses

Use for relief of occasional sleeplessness

Warnings

Warnings Do not use in children under 12 years of age with any other product containing diphenhydramine, even one used on skin Ask a doctor before use if you have a breathing problem such as emphysema or chronic bronchitis glaucoma trouble urinating due to an enlarged prostate gland Ask a doctor or pharmacist before use if you are taking sedatives or tranquilizers When using this product avoid alcoholic drinks drowsiness will occur do not drive a motor vehicle or operate machinery Stop use and ask a doctor if sleeplessness persists continuously for more than 2 weeks. Insomnia may be a symptom of serious underlying medical illness. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. Overdose warning In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222)

Do not use

Do not use in children under 12 years of age with any other product containing diphenhydramine, even one used on skin

Ask a doctor before use

Ask a doctor before use if you have a breathing problem such as emphysema or chronic bronchitis glaucoma trouble urinating due to an enlarged prostate gland

Ask a doctor or pharmacist

Ask a doctor or pharmacist before use if you are taking sedatives or tranquilizers

When using this product

When using this product avoid alcoholic drinks drowsiness will occur do not drive a motor vehicle or operate machinery

Stop use and ask a doctor

Stop use and ask a doctor if sleeplessness persists continuously for more than 2 weeks. Insomnia may be a symptom of serious underlying medical illness.

Pregnancy or breast-feeding

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children

Keep out of reach of children.

Directions

Directions adults and children 12 years and over take 2 caplets at bedtime if needed, or as directed by a doctor children under 12 years do not use

Other information

Other information each caplet contains: calcium 15 mg store between 20-25°C (68-77°F). Avoid high humidity. Protect from light. do not use if carton tape or foil inner seal imprinted with "SAFETY SEAL®" is broken or missing

Inactive ingredients

Inactive ingredients carnauba wax, croscarmellose sodium, dibasic calcium phosphate, FD&C Blue no. 1 aluminum lake, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate 80, titanium dioxide

Questions?

Questions or comments? call 1-877-895-3665 (toll-free) or 215-273-8755 (collect)

Label text from the FDA structured product label by Kenvue Brands LLC (revised Jun 2, 2025). Long sections are shortened; the complete label is on DailyMed.

Active ingredients

Simply Sleep NDC products (1)

NDCStrength & formLabelerType
50580-843Diphenhydramine Hydrochloride 25 mg/1
Tablet, Film Coated
Kenvue Brands LLCOTC MONOGRAPH DRUG

Frequently asked questions

What is Simply Sleep used for?

Use for relief of occasional sleeplessness

Who makes Simply Sleep?

Simply Sleep is listed by 1 labeler in the FDA NDC directory, including Kenvue Brands LLC.