Sinu-Phen Plus
Acetaminophen, Phenylephrine Hydrochloride · Tablet · Oral
Active ingredient
Active ingredients (in each tablet) Acetaminophen 500mg Phenylephrine HCl 5mg
Purpose
Purpose Pain reliever/fever reducer Nasal decongestant
Uses
Uses temporarily relieves these common cold/flu symptoms: nasal congestion headache minor aches and pains stuffy nose sinus congestion and pressure temporarily reduces fever
Warnings
Warnings Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take: more than 4,000 mg of acetaminophen in 24 hours with other drugs containing acetaminophen 3 or more alcoholic drinks every day while using this product Allergy alert: Acetaminophen may cause severe skin reactions. Symptoms may include: skin reddening blisters rash If a skin reaction occurs, stop use and seek medical help right away. DO NOT USE Do not use with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. for more than 10 days unless directed by a doctor ASK DOCTOR Ask a doctor before use if you have liver disease thyroid disease diabetes high blood pressure heart disease trouble urinating due to an enlarged prostate gland ASK DOCTOR/PHARMACIST Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin WHEN USING When using this product do not exceed recommended dosage. STOP USE Stop use and ask a doctor if you get nervous, dizzy, or sleepless pain or nasal congestion gets worse or lasts more than 7 days fever gets worse or lasts more than 3 days redness or swelling is present new symptoms appear These could be signs of a serious condition. PREGNANCY OR BREAST FEEDING If pregnant or breast-feeding, ask a health professional before use. KEEP OUT OF REACH OF CHILDREN Keep out of reach of children. Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222). Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.
Do not use
Do not use with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. for more than 10 days unless directed by a doctor
Ask a doctor before use
Ask a doctor before use if you have liver disease thyroid disease diabetes high blood pressure heart disease trouble urinating due to an enlarged prostate gland
Ask a doctor or pharmacist
Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin
When using this product
When using this product do not exceed recommended dosage.
Stop use and ask a doctor
Stop use and ask a doctor if you get nervous, dizzy, or sleepless pain or nasal congestion gets worse or lasts more than 7 days fever gets worse or lasts more than 3 days redness or swelling is present new symptoms appear These could be signs of a serious condition.
Pregnancy or breast-feeding
If pregnant or breast-feeding, ask a health professional before use.
Keep out of reach of children
Keep out of reach of children. Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222). Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.
Directions
Directions do not use more than directed Adults and children: (12 years and over) Take 2 tablets every 6 hours. Do not take more than 8 tablets in 24 hours. Children under 12 years: Ask a doctor
Inactive ingredients
Inactive ingredients corn starch, crospovidone, hypromelloses, microcrystalline cellulose, polyethylene glycol, povidone, pregelatinized starch, stearic acid.
Questions?
Questions or comments? (888) 602-0288
Label text from the FDA structured product label by Wildman Business Group (revised Jan 12, 2026). Long sections are shortened; the complete label is on DailyMed.
Active ingredients
- Acetaminophen in 1 product
- Phenylephrine Hydrochloride in 1 product
Sinu-Phen Plus NDC products (1)
| NDC | Strength & form | Labeler | Type |
|---|---|---|---|
| 84269-2546 | Acetaminophen 500 mg/1; Phenylephrine Hydrochloride 5 mg/1 Tablet | Wildman Business Group | OTC MONOGRAPH DRUG |
Frequently asked questions
What is Sinu-Phen Plus used for?
Uses temporarily relieves these common cold/flu symptoms: nasal congestion headache minor aches and pains stuffy nose sinus congestion and pressure temporarily reduces fever
Who makes Sinu-Phen Plus?
Sinu-Phen Plus is listed by 1 labeler in the FDA NDC directory, including Wildman Business Group.