Sominex

Diphenhydramine Hydrochloride · Tablet, Film Coated · Oral

Over the counter Histamine-1 Receptor Antagonist

Active ingredient

Active i ngredient (in each cap let) Diphenhydramine HCl 25 mg

Purpose

Purpose Nighttime sleep-aid

Uses

Use helps reduce difficultly falling asleep

Warnings

Warnings Do not use in children under 12 years of age with any other product containing diphenhydramine, even one used on skin with other antihistamines Ask a doctor before use if you have a breathing problem such as emphysema or chronic bronchitis glaucoma trouble urinating due to an enlarged prostate gland Ask a doctor or pharmacist before use if you are taking sedatives or tranquilizers When using this product avoid alcoholic beverages be careful when driving a motor vehicle or operating machinery drowsiness will occur Stop use and ask a doctor if sleeplessness persists continuously for more than 2 weeks. Insomnia may be a symptom of serious underlying medical illness. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. In case of o verdose , get medical help or contact a Poison Control Center (1-800-222-1222) right away.

Do not use

Do not use in children under 12 years of age with any other product containing diphenhydramine, even one used on skin with other antihistamines

Ask a doctor before use

Ask a doctor before use if you have a breathing problem such as emphysema or chronic bronchitis glaucoma trouble urinating due to an enlarged prostate gland

Ask a doctor or pharmacist

Ask a doctor or pharmacist before use if you are taking sedatives or tranquilizers

When using this product

When using this product avoid alcoholic beverages be careful when driving a motor vehicle or operating machinery drowsiness will occur

Stop use and ask a doctor

Stop use and ask a doctor if sleeplessness persists continuously for more than 2 weeks. Insomnia may be a symptom of serious underlying medical illness.

Pregnancy or breast-feeding

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children

Keep out of reach of children. In case of o verdose , get medical help or contact a Poison Control Center (1-800-222-1222) right away.

Directions

Directions adults and children 12 years and older : take 2 tablets at bedtime if needed, or as directed by your doctor

Inactive ingredients

Inactive ingredients croscarmellose sodium, dicalcium phosphate, FD&C blue no. 1 lake, hypromellose, lactose, magnesium stearate, microcrystalline cellulose, mineral oil, silica, stearate acid, talc, titanium dioxide, triacetin

Questions?

Questions? 1-866-255-5202

Label text from the FDA structured product label by Medtech Products Inc. (revised Oct 23, 2025). Long sections are shortened; the complete label is on DailyMed.

Active ingredients

Sominex NDC products (2)

NDCStrength & formLabelerType
63029-554Diphenhydramine Hydrochloride 25 mg/1
Tablet, Film Coated
Medtech Products Inc.OTC MONOGRAPH DRUG
67751-221Diphenhydramine Hydrochloride 25 mg/1
Tablet, Film Coated
Navajo Manufacturing Company Inc.OTC MONOGRAPH DRUG

Frequently asked questions

What is Sominex used for?

Use helps reduce difficultly falling asleep

Who makes Sominex?

Sominex is listed by 2 labelers in the FDA NDC directory, including Medtech Products Inc., Navajo Manufacturing Company Inc..