Soothe

Bismuth subsalicylate · Liquid · Oral, Ophthalmic

Over the counter Bismuth Non-Standardized Chemical Allergen Blood Coagulation Factor

Active ingredient

Active ingredient (in each 30 mL dose) Bismuth subsalicylate 525 mg

Purpose

Purpose Upset stomach reliever/Antidiarrheal

Uses

Uses relieves travelers' diarrhea diarrhea upset stomach due to overindulgence in food and drink, including: heartburn indigestion nausea gas fullness belching

Warnings

Warnings Reye's syndrome : Children and teenagers who have or are recovering from chicken pox or flu-like symptoms should not use this product. When using this product, if changes in behavior with nausea and vomiting occur, consult a doctor because these symptoms could be an early sign of Reye's syndrome, a rare but serious illness. Allergy alert: Contains salicylate. Do not take if you are allergic to salicylates (including aspirin) taking other salicylate products Do not use if you have an ulcer a bleeding problem bloody or black stool Ask a doctor before use if you have fever mucus in the stool Ask a doctor or pharmacist before use if you are taking any drug for diabetes gout arthritis anticoagulation (thinning the blood) When using this product a temporary, but harmless, darkening of the stool and/or tongue may occur. Stop use and ask a doctor if symptoms get worse or last more than 2 days ringing in the ears or loss of hearing occurs diarrhea lasts more than 2 days If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of childen. In case of overdose, get medical help or contact a Poison Control Center (1-800-222-1222) right away.

Do not use

Do not use if you have an ulcer a bleeding problem bloody or black stool

Ask a doctor before use

Ask a doctor before use if you have fever mucus in the stool

Ask a doctor or pharmacist

Ask a doctor or pharmacist before use if you are taking any drug for diabetes gout arthritis anticoagulation (thinning the blood)

When using this product

When using this product a temporary, but harmless, darkening of the stool and/or tongue may occur.

Stop use and ask a doctor

Stop use and ask a doctor if symptoms get worse or last more than 2 days ringing in the ears or loss of hearing occurs diarrhea lasts more than 2 days

Pregnancy or breast-feeding

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children

Keep out of reach of childen. In case of overdose, get medical help or contact a Poison Control Center (1-800-222-1222) right away.

Directions

Directions mL = milliliter shake well before using measure only with dosing cup provided. Do not use any other dosing device. keep dosing cup with product adults and children 12 years and over 30 mL (1 dose) every 1/2 or 60 mL (2 doses) every hour as needed for diarrhea/traveler's diarrhea 30 mL (1 dose) every 1/2 hour as needed for overindulgence (upset stomach, heartburn, indigestion, nausea) do not exceed 8 doses (240 mL) in 24 hours use until diarrhea stops but not more than 2 days children under 12 years of age: ask a doctor drink plenty of clear fluids to help prevent dehydration caused by diarrhea

Other information

Other information each 30 mL contains : sodium 9 mg each 30 mL contains : salicylate 206 mg low sodium keep tightly closed protect from freezing avoid excessive heat (over 104ºF or 40ºC)

Inactive ingredients

Inactive ingredients benzoic acid, D&C red #22, D&C red #28, flavor, glycerin, purified water, sucralose, xanthan gum

Questions?

Questions or comments? Call 1-877-753-3935 Monday-Friday 9AM-5PM EST

Label text from the FDA structured product label by Walgreens (revised Jun 25, 2026). Long sections are shortened; the complete label is on DailyMed.

Active ingredients

Soothe NDC products (6)

NDCStrength & formLabelerType
24208-495Glycerin 6 mg/mL; Propylene Glycol 6 mg/mL
Solution/ Drops
Bausch & Lomb IncorporatedOTC MONOGRAPH DRUG
0363-5960Calcium Carbonate 400 mg/1
Tablet, Chewable
Walgreen CompanyOTC MONOGRAPH DRUG
0363-0073Bismuth Subsalicylate 525 mg/30mL
Liquid
WalgreensOTC MONOGRAPH DRUG
0363-0736Bismuth Subsalicylate 525 mg/30mL
Liquid
WalgreensOTC MONOGRAPH DRUG
0363-7240Bismuth Subsalicylate 525 mg/30mL
Liquid
WalgreensOTC MONOGRAPH DRUG
0363-7370Bismuth Subsalicylate 525 mg/15mL
Liquid
WalgreensOTC MONOGRAPH DRUG

Frequently asked questions

What is Soothe used for?

Uses relieves travelers' diarrhea diarrhea upset stomach due to overindulgence in food and drink, including: heartburn indigestion nausea gas fullness belching

Who makes Soothe?

Soothe is listed by 3 labelers in the FDA NDC directory, including Bausch & Lomb Incorporated, Walgreen Company, Walgreens.