Spot Defy

Sulfur · Lotion · Topical

Over the counter

Active ingredient

active ingredient sulfur 5%

Purpose

purpose acne treatment

Uses

indications clears acne pimples

Warnings

warnings for external use only. keep out of reach of children. when using this product skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. if irritation occurs, only use one topical acne medication at a time. do not use on broken skin or large areas of the skin. when using this product apply only to areas with acne.

Do not use

do not use on broken skin or large areas of the skin.

When using this product

when using this product skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. if irritation occurs, only use one topical acne medication at a time. when using this product apply only to areas with acne.

Keep out of reach of children

keep out of reach of children.

Directions

directions clean the skin thoroughly before applying this product. cover the entire affected area with a thin layer at night. if bothersome dryness or peeling occurs, reduce application to every other night.

Inactive ingredients

inactive ingredients Water (Aqua, Eau), Kaolin, Cetearyl Alcohol, Glyceryl Stearate SE, Glycerin, Butylene Glycol, Bentonite, Acacia Senegal Gum, Phenoxyethanol, Niacinamide, Maltodextrin, Ethylhexylglycerin, Sodium PCA, Xanthan Gum, Tocopheryl Acetate, Syringa Vulgaris (Lilac) Extract, Quartz, Dipotossium Glycyrrhizate, Centella Asiatica Extract, Hibiscus Rosa-Sinensis Flower Extract, Lavandula Angustifolia (Lavender) Extract, Origanum Vulgare Leaf Extract, Thymus Vulgaris (Thyme) Extract

Questions?

questions? call 1.800.433.6650 monday - friday 7:30am - 4:30 pm mst

Label text from the FDA structured product label by Bioelements, Inc. (revised Dec 17, 2025). Long sections are shortened; the complete label is on DailyMed.

Active ingredients

Spot Defy NDC products (1)

NDCStrength & formLabelerType
49825-200Sulfur 50 mg/mL
Lotion
Bioelements, Inc.OTC MONOGRAPH DRUG

Frequently asked questions

What is Spot Defy used for?

indications clears acne pimples

Who makes Spot Defy?

Spot Defy is listed by 1 labeler in the FDA NDC directory, including Bioelements, Inc..