SPOTLESS 30-Day Regimen
Benzoyl Peroxide · Kit · Topical
Active ingredient
Active ingredient Benzoyl peroxide 5% Active ingredient Benzoyl peroxide 2.5%
Purpose
Purpose Acne treatment Purpose Acne treatment
Uses
Uses for the treatment of acne helps keep skin clear of new acne blemishes, acne pimples, blackheads and whiteheads Uses for the treatment of acne helps keep skin clear of new acne blemishes, acne pimples, blackheads and whiteheads
Warnings
Warnings For external use only Do not use if you have very sensitive skin are sensitive to benzoyl peroxide When using this product skin irritation may occur, characterized by redness, burning, itching, peeling or possibly swelling. Irritation may be reduced by using the product less frequently or in a lower concentration. skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time. avoid unnecessary sun exposure and use a sunscreen avoid contact with the eyes, lips and mouth avoid contact with hair and dyed fabrics, which may be bleached by this product Stop use and ask a doctor if irritation becomes severe Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away. Warnings For external use only Do not use if you have very sensitive skin are sensitive to benzoyl peroxide When using this product skin irritation may occur, characterized by redness, burning, itching, peeling or possibly swelling. Irritation may be reduced by using the product less frequently or in a lower concentration. skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time. avoid unnecessary sun exposure and use a sunscreen avoid contact with the eyes, lips and mouth avoid contact with hair and dyed fabrics, which may be bleached by this product Stop use and ask a doctor if irritation becomes severe Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.
Do not use
Do not use if you have very sensitive skin are sensitive to benzoyl peroxide Do not use if you have very sensitive skin are sensitive to benzoyl peroxide
When using this product
When using this product skin irritation may occur, characterized by redness, burning, itching, peeling or possibly swelling. Irritation may be reduced by using the product less frequently or in a lower concentration. skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time. avoid unnecessary sun exposure and use a sunscreen avoid contact with the eyes, lips and mouth avoid contact with hair and dyed fabrics, which may be bleached by this product When using this product skin irritation may occur, characterized by redness, burning, itching, peeling or possibly swelling. Irritation may be reduced by using the product less frequently or in a lower concentration. skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time. avoid unnecessary sun exposure and use a sunscreen avoid contact with the eyes, lips and mouth avoid contact with hair and dyed fabrics, which may be bleached by this product
Stop use and ask a doctor
Stop use and ask a doctor if irritation becomes severe Stop use and ask a doctor if irritation becomes severe
Keep out of reach of children
Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away. Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.
Directions
Directions wet skin with lukewarm water using fingertips, apply a thin, even layer and massage over entire face for 90 seconds, avoiding all contact with eyes rinse thoroughly and pat dry use once daily and increase to twice daily as tolerated wash hands after application to help avoid staining fabrics because excessive drying of the skin may occur, start with one application daily, then gradually increase to two or three times daily if needed or as directed by a doctor if bothersome dryness or peeling occurs, reduce application to once a day or every other day if going outside, apply sunscreen after using this product. If irritation or sensitivity develops, stop use of both products and ask a doctor. Directions clean the skin thoroughly before applying this product dispense 1-2 pumps and cover the entire affected area with a thin, even layer one to three times daily do not rinse product off face wash hands after application to help avoid staining fabrics because excessive drying of the skin may occur, start with one application daily, then gradually increase to two or three times daily if needed or as directed by a doctor if bothersome dryness or peeling occurs, reduce application to once a day or every other day if going outside, apply sunscreen after using this product. If irritation or sensitivity develops, stop use of both products and ask a doctor.
Inactive ingredients
Inactive ingredients water, polyacrylamide, C13-14 isoalkane, jojoba esters, carbomer, diethylhexyl sodium sulfosuccinate, cocamidopropyl betaine, laureth-7, sodium chloride, sodium citrate, sodium hydroxide, propanediol, ethylhexylglycerin, phenoxyethanol, sodium benzoate Inactive ingredients water/aqua/eau, glycereth-18 ethylhexanoate, glycereth-18, disiloxane, glycerin, butylene glycol, propanediol, acrylamide/sodium acryloyldimethyltaurate copolymer, allantoin, ascorbyl palmitate, bisabolol, myristyl alcohol, PCA, phytosteryl/octyldodecyl lauroyl glutamate, polygonum cuspidatum root extract, sodium hyaluronate, zingiber officinale (ginger) root extract, fragrance/parfum, carbomer, methyl methacrylate crosspolymer, cetyl hydroxyethylcellulose, hydroxyphenyl propamidobenzoic acid, polyglyceryl-2 isostearate, polysorbate 80, sorbitan oleate, xanthan gum, diethylhexyl sodium sulfosuccinate, isohexadecane, dimethyl isosorbide, tocopherol, citric acid, sodium citrate, sodium hydroxide, caprylyl glycol, decylene glycol, hexylene glycol, pentylene glycol, 1,2-hexanediol, ethylhexylglycerin, hydroxyacetophenone, phenoxyethanol, citral, citronellol, limonene, linalool, carvone, citrus aurantium peel oil, mentha viridis (spearmint) leaf oil, pinene, mica, tin oxide, titanium dioxide (CI 77891), blue 1 (CI 42090), ext. violet 2 (CI 60730), red 33 (CI 17200)
Questions?
Questions? 1-888-995-5656 Questions? 1-888-995-5656
Label text from the FDA structured product label by Rodan & Fields (revised Feb 4, 2026). Long sections are shortened; the complete label is on DailyMed.
SPOTLESS 30-Day Regimen NDC products (1)
| NDC | Strength & form | Labeler | Type |
|---|---|---|---|
| 14222-1602 | Kit | Rodan & Fields | OTC MONOGRAPH DRUG |
Frequently asked questions
What is SPOTLESS 30-Day Regimen used for?
Uses for the treatment of acne helps keep skin clear of new acne blemishes, acne pimples, blackheads and whiteheads Uses for the treatment of acne helps keep skin clear of new acne blemishes, acne pimples, blackheads and whiteheads
Who makes SPOTLESS 30-Day Regimen?
SPOTLESS 30-Day Regimen is listed by 1 labeler in the FDA NDC directory, including Rodan & Fields.