Thompson Cramp Relief

Acetaminophen, Pamabrom, Pyrilamine maleate · Tablet, Film Coated · Oral

Over the counter

Active ingredient

Active ingredient (in each caplet) Acetaminophen 500 mg Pamabrom 25 mg Pyrilamine maleate 15 mg

Purpose

Purpose Pain reliever Diuretic Antihistamine

Uses

Uses for the temporary relief of these symptoms associated with menstrual periods: ■ headache ■ bloating ■ cramps ■ backache ■ muscular aches ■ irritability ■ water-weight gain

Warnings

Warnings Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take ■ more than 4,000 mg of acetaminophen in 24 hours ■ with other drugs containing acetaminophen ■ 3 or more alcoholic drinks every day while using this product Allergy alert: Acetaminophen may cause severe skin reactions. Symptoms may include: ■ skin reddening ■ blisters ■ rash If a skin reaction occurs, stop use and seek medical help right away.

Do not use

Do not use ■ with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. ■ if you have ever had an allergic reaction to this product or any of its ingredients

Ask a doctor before use

Ask a doctor before use if you have ■ difficulty in urination due to enlargement of the prostate gland ■ a breathing problem such as emphysema or chronic bronchitis ■ liver disease ■ glaucoma

Ask a doctor or pharmacist

Ask a doctor or pharmacist before use if you are ■ taking sedatives or tranquilizers ■ taking the blood thinning drug warfarin

When using this product

When using this product ■ drowsiness may occur ■ avoid alcoholic beverages ■ excitability may occur, especially in children ■ alcohol, sedatives and tranquilizers may increase drowsiness ■ use caution when driving a motor vehicle or operating machinery

Stop use and ask a doctor

Stop use and ask a doctor if ■ pain gets worse or lasts more than 10 days ■ fever gets worse or lasts more than 3 days ■ new symptoms occur ■ redness or swelling is present These could be signs of a serious condition.

Pregnancy or breast-feeding

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children

Keep out of reach of children. In case of accidental overdose, get medical help or contact a Poison Control Center (1-800-222-1222) right away. Prompt medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.

Directions

Directions ■ do not take more than directed Adults and children: (12 years and over) ■ take 2 caplets with water every 6 hours as needed ■ do not exceed 6 caplets in a 24 hour period or as directed by a doctor Children under 12 years: ask a doctor

Inactive ingredients

Inactive ingredients corn starch, croscarmellose sodium, crospovidone, FD&C blue #2 aluminum lake, FD&C red #40 aluminum lake, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polyvinyl alcohol, povidone, shellac wax, silicon dioxide, stearic acid, talc, titanium dioxide

Questions?

Questions or comments? 877.506.4291

Label text from the FDA structured product label by Thompson Safety (revised Jan 8, 2026). Long sections are shortened; the complete label is on DailyMed.

Active ingredients

Thompson Cramp Relief NDC products (1)

NDCStrength & formLabelerType
73408-923Acetaminophen 500 mg/1; Pamabrom 25 mg/1; Pyrilamine Maleate 15 mg/1
Tablet, Film Coated
Thompson SafetyOTC MONOGRAPH DRUG

Frequently asked questions

What is Thompson Cramp Relief used for?

Uses for the temporary relief of these symptoms associated with menstrual periods: ■ headache ■ bloating ■ cramps ■ backache ■ muscular aches ■ irritability ■ water-weight gain

Who makes Thompson Cramp Relief?

Thompson Cramp Relief is listed by 1 labeler in the FDA NDC directory, including Thompson Safety.