tussin

Dextromethorphan HBr, Guaifenesin · Solution · Oral

Over the counter Expectorant Sigma-1 Agonist Uncompetitive N-methyl-D-aspartate Receptor Antagonist

Active ingredient

Active ingredients (in each 20 mL) Dextromethorphan HBr, USP 20 mg Guaifenesin, USP 200 mg

Purpose

Purposes Cough suppressant Expectorant

Uses

Uses
• temporarily relieves cough due to minor throat and bronchial irritation as may occur with a cold
• helps loosen phlegm (mucus) and thin bronchial secretions to drain bronchial tubes

Warnings

Warnings Do not use if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. Ask a doctor before use if you have
• cough that occurs with too much phlegm (mucus)
• cough that lasts or is chronic such as occurs with smoking, asthma, chronic bronchitis, or emphysema Stop use and ask a doctor if cough lasts for more than 7 days, comes back, or is accompanied by fever, rash, or persistent headache. A persistent cough may be a sign of a serious condition. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222).

Do not use

Do not use if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.

Ask a doctor before use

Ask a doctor before use if you have
• cough that occurs with too much phlegm (mucus)
• cough that lasts or is chronic such as occurs with smoking, asthma, chronic bronchitis, or emphysema

Stop use and ask a doctor

Stop use and ask a doctor if cough lasts for more than 7 days, comes back, or is accompanied by fever, rash, or persistent headache. A persistent cough may be a sign of a serious condition.

Pregnancy or breast-feeding

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children

Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222).

Directions

Directions
• do not take more than 6 doses in any 24-hour period
• measure only with dosing cup provided
• keep dosing cup with product
• mL = milliliter
• this adult product is not intended for use in children under 12 years of age age dose adults and children 12 years and over 20 mL every 4 hours children under 12 years do not use

Inactive ingredients

Inactive ingredients anhydrous citric acid, FD&C red no. 40, flavor, glycerin, propylene glycol, purified water, sodium benzoate, sodium citrate, sorbitol solution, sucralose, xanthan gum

Questions?

Questions or comments? 1-800-719-9260

Label text from the FDA structured product label by Safeway (revised Jul 28, 2026). Long sections are shortened; the complete label is on DailyMed.

Active ingredients

tussin NDC products (8)

NDCStrength & formLabelerType
63941-382Dextromethorphan Hydrobromide 20 mg/10mL; Guaifenesin 200 mg/10mL; Phenylephrine Hydrochloride 10 mg/10mL
Liquid
Best Choice (Valu Merchandisers Company)OTC MONOGRAPH DRUG
70000-0133Dextromethorphan Hydrobromide 20 mg/10mL; Guaifenesin 200 mg/10mL; Phenylephrine Hydrochloride 10 mg/10mL
Liquid
Cardinal Health (Leader) 70000OTC MONOGRAPH DRUG
53943-507Guaifenesin 100 mg/5mL
Liquid
Discount Drug MartOTC MONOGRAPH DRUG
37808-639Dextromethorphan Hydrobromide 20 mg/20mL; Guaifenesin 400 mg/20mL
Solution
H E BOTC MONOGRAPH DRUG
59640-100Dextromethorphan Hydrobromide 20 mg/20mL; Guaifenesin 200 mg/20mL
Solution
H E BOTC MONOGRAPH DRUG
21130-454Dextromethorphan Hydrobromide 20 mg/20mL; Guaifenesin 200 mg/20mL
Solution
SafewayOTC MONOGRAPH DRUG
21130-707Dextromethorphan Hydrobromide 20 mg/20mL; Guaifenesin 400 mg/20mL
Solution
SafewayOTC MONOGRAPH DRUG
70677-1186Guaifenesin 200 mg/10mL
Solution
Strategic Sourcing ServicesOTC MONOGRAPH DRUG

Frequently asked questions

What is tussin used for?

Uses • temporarily relieves cough due to minor throat and bronchial irritation as may occur with a cold • helps loosen phlegm (mucus) and thin bronchial secretions to drain bronchial tubes

Who makes tussin?

tussin is listed by 6 labelers in the FDA NDC directory, including Best Choice (Valu Merchandisers Company), Cardinal Health (Leader) 70000, Discount Drug Mart, H E B.